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Debiased machine learning estimators for smooth functionals in nonparametric models can exhibit substantial variability and instability, often leading practitioners to instead rely on parametric or semiparametric working models. Such…

Methodology · Statistics 2026-03-20 Lars van der Laan , Marco Carone , Alex Luedtke , Mark van der Laan

We develop a unified framework for automatic debiased machine learning (autoDML) for inference on a broad class of statistical parameters. The framework applies to any smooth functional of a nonparametric M-estimand, defined as the…

Methodology · Statistics 2026-03-23 Lars van der Laan , Aurelien Bibaut , Nathan Kallus , Alex Luedtke

Precision medicine is of considerable interest in clinical, academic and regulatory parties. The key to precision medicine is the optimal treatment regime. Recently, Zhou et al. (2017) developed residual weighted learning (RWL) to construct…

Methodology · Statistics 2017-11-30 Xin Zhou , Michael R. Kosorok

In linear regression, the least squares (LS) estimator has certain optimality properties if the errors are normally distributed. This assumption is often violated in practice, partly caused by data outliers. Robust estimators can cope with…

Methodology · Statistics 2020-07-01 Sukru Acitas , Peter Filzmoser , Birdal Senoglu

Automated model selection is often proposed to users to choose which machine learning model (or method) to apply to a given regression task. In this paper, we show that combining different regression models can yield better results than…

Machine Learning · Computer Science 2022-06-24 Patrick Echtenbruck , Martina Echtenbruck , Joost Batenburg , Thomas Bäck , Boris Naujoks , Michael Emmerich

For high-dimensional linear regression models, we review and compare several estimators of variances $\tau^2$ and $\sigma^2$ of the random slopes and errors, respectively. These variances relate directly to ridge regression penalty…

Computation · Statistics 2019-02-08 Jurre R. Veerman , Gwenael G. R. Leday , Mark A. van de Wiel

Much of the focus in machine learning research is placed in creating new architectures and optimization methods, but the overall loss function is seldom questioned. This paper interprets machine learning from a multi-objective optimization…

Machine Learning · Statistics 2015-07-22 Conrado Silva Miranda , Fernando José Von Zuben

This paper presents a minimalist neural regression network as an aggregate of independent identical regression blocks that are trained simultaneously. Moreover, it introduces a new multiplicative parameter, shared by all the neural units of…

Machine Learning · Computer Science 2016-07-06 Soheil Keshmiri

We develop an estimator for treatment effects in high-dimensional settings with additive measurement error, a prevalent challenge in modern econometrics. We introduce the Double/Debiased Convex Conditioned LASSO (Double/Debiased CoCoLASSO),…

Econometrics · Economics 2024-08-28 Geonwoo Kim , Suyong Song

We consider a natural semi-online model for weighted paging, where at any time the algorithm is given predictions, possibly with errors, about the next arrival of each page. The model is inspired by Belady's classic optimal offline…

Data Structures and Algorithms · Computer Science 2021-11-10 Nikhil Bansal , Christian Coester , Ravi Kumar , Manish Purohit , Erik Vee

Externally controlled single-arm trials are critical to assess treatment efficacy across therapeutic indications for which randomized controlled trials are not feasible. A closely-related research design, the unanchored indirect treatment…

Methodology · Statistics 2026-02-13 Harlan Campbell , Antonio Remiro-Azócar

We introduce a family of interpretable machine learning models, with two broad additions: Linearised Additive Models (LAMs) which replace the ubiquitous logistic link function in General Additive Models (GAMs); and SubscaleHedge, an expert…

Machine Learning · Computer Science 2022-11-14 Danial Dervovic , Nicolas Marchesotti , Freddy Lecue , Daniele Magazzeni

Doubly robust estimators are widely used for estimating average treatment effects and other linear summaries of regression functions. While consistency requires only one of two nuisance functions to be estimated consistently, asymptotic…

Methodology · Statistics 2025-07-01 Lars van der Laan , Alex Luedtke , Marco Carone

When we are interested in high-dimensional system and focus on classification performance, the $\ell_{1}$-penalized logistic regression is becoming important and popular. However, the Lasso estimates could be problematic when penalties of…

Machine Learning · Statistics 2020-06-12 Huamei Huang , Yujing Gao , Huiming Zhang , Bo Li

Post-Double-Lasso is becoming the most popular method for estimating linear regression models with many covariates when the purpose is to obtain an accurate estimate of a parameter of interest, such as an average treatment effect. However,…

Econometrics · Economics 2025-11-27 Sullivan Hué , Sébastien Laurent , Ulrich Aiounou , Emmanuel Flachaire

We propose a new approach, along with refinements, based on $L_1$ penalties and aimed at jointly estimating several related regression models. Its main interest is that it can be rewritten as a weighted lasso on a simple transformation of…

Methodology · Statistics 2014-11-07 Edouard Ollier , Vivian Viallon

Boosting is a popular algorithm in supervised machine learning with wide applications in regression and classification problems. It combines weak learners, such as regression trees, to obtain accurate predictions. However, in the presence…

Computation · Statistics 2025-02-06 Zhu Wang

Machine learning methods, particularly the double machine learning (DML) estimator (Chernozhukov et al., 2018), are increasingly popular for the estimation of the average treatment effect (ATE). However, datasets often exhibit unbalanced…

Econometrics · Economics 2024-06-12 Daniele Ballinari

This paper discusses and evaluates ideas of data balancing and data augmentation in the context of mathematical objects: an important topic for both the symbolic computation and satisfiability checking communities, when they are making use…

Symbolic Computation · Computer Science 2023-08-21 Tereso del Rio , Matthew England

Imputing missing potential outcomes using an estimated regression function is a natural idea for estimating causal effects. In the literature, estimators that combine imputation and regression adjustments are believed to be comparable to…

Statistics Theory · Mathematics 2023-01-20 Zhexiao Lin , Fang Han
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