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Medical imaging tasks are very challenging due to the lack of publicly available labeled datasets. Hence, it is difficult to achieve high performance with existing deep-learning models as they require a massive labeled dataset to be trained…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Anubhav Gupta , Islam Osman , Mohamed S. Shehata , John W. Braun

Although artificial intelligence (AI) has made significant progress in understanding molecules in a wide range of fields, existing models generally acquire the single cognitive ability from the single molecular modality. Since the hierarchy…

Machine Learning · Computer Science 2022-09-14 Bing Su , Dazhao Du , Zhao Yang , Yujie Zhou , Jiangmeng Li , Anyi Rao , Hao Sun , Zhiwu Lu , Ji-Rong Wen

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Haoyu Dong , Yuwen Chen , Hanxue Gu , Nicholas Konz , Yaqian Chen , Qihang Li , Maciej A. Mazurowski

Foundation models (FM) have transformed computational pathology but remain computationally prohibitive for clinical deployment due to their massive parameter counts and high-magnification processing requirements. Here, we introduce XMAG, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Anil V. Parwani , Muhammad Khalid Khan Niazi

Medical artificial general intelligence (AGI) is an emerging field that aims to develop systems specifically designed for medical applications that possess the ability to understand, learn, and apply knowledge across a wide range of tasks…

Artificial Intelligence · Computer Science 2023-06-21 Juexiao Zhou , Xiuying Chen , Xin Gao

Medical multi-modal pre-training has revealed promise in computer-aided diagnosis by leveraging large-scale unlabeled datasets. However, existing methods based on masked autoencoders mainly rely on data-level reconstruction tasks, but lack…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yupei Zhang , Li Pan , Qiushi Yang , Tan Li , Zhen Chen

Recent advances in generative AI have brought incredible breakthroughs in several areas, including medical imaging. These generative models have tremendous potential not only to help safely share medical data via synthetic datasets but also…

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Generative models have revolutionized Artificial Intelligence (AI), particularly in multimodal applications. However, adapting these models to the medical domain poses unique challenges due to the complexity of medical data and the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Daniele Molino , Francesco di Feola , Linlin Shen , Paolo Soda , Valerio Guarrasi

Magnetic Resonance Imaging (MRI) is indispensable in clinical practice but remains constrained by fragmented, multi-stage workflows encompassing acquisition, reconstruction, segmentation, detection, diagnosis, and reporting. While deep…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xingxin He , Aurora Rofena , Ruimin Feng , Haozhe Liao , Zhaoye Zhou , Albert Jang , Fang Liu

Current medical AI systems are often limited to narrow applications, hindering widespread adoption. We present MedVersa, a generalist foundation model trained on tens of millions of compiled medical instances. MedVersa unlocks generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Hong-Yu Zhou , Julián Nicolás Acosta , Subathra Adithan , Suvrankar Datta , Eric J. Topol , Pranav Rajpurkar

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang

We present a self-supervised, time-to-event (TTE) foundation model called MOTOR (Many Outcome Time Oriented Representations) which is pretrained on timestamped sequences of events in electronic health records (EHR) and health insurance…

Machine Learning · Computer Science 2023-12-06 Ethan Steinberg , Jason Fries , Yizhe Xu , Nigam Shah

This paper introduces a new metamodel-based knowledge representation that significantly improves autonomous learning and adaptation. While interest in hybrid machine learning / symbolic AI systems leveraging, for example, reasoning and…

Artificial Intelligence · Computer Science 2021-02-12 Hugo Latapie , Ozkan Kilic , Gaowen Liu , Yan Yan , Ramana Kompella , Pei Wang , Kristinn R. Thorisson , Adam Lawrence , Yuhong Sun , Jayanth Srinivasa

Multimodal clinical prediction faces three challenges: multiple foundation models (FMs) with complementary strengths per modality, pervasive missing modalities at training and test time, and sample-specific variation in modality…

Machine Learning · Computer Science 2026-05-19 Seungik Cho , Anqi Li , Wei Qiu

Machine learning (ML) applications in medical artificial intelligence (AI) systems have shifted from traditional and statistical methods to increasing application of deep learning models. This survey navigates the current landscape of…

Machine Learning · Computer Science 2024-01-23 Elisa Warner , Joonsang Lee , William Hsu , Tanveer Syeda-Mahmood , Charles Kahn , Olivier Gevaert , Arvind Rao

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yunhe Gao , Yabin Zhang , Chong Wang , Jiaming Liu , Maya Varma , Jean-Benoit Delbrouck , Akshay Chaudhari , Curtis Langlotz

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed