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The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Medical imaging provides essential visual insights for diagnosis, and multimodal large language models (MLLMs) are increasingly utilized for its analysis due to their strong generalization capabilities; however, the underlying factors…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zhenyang Cai , Junying Chen , Rongsheng Wang , Weihong Wang , Yonglin Deng , Dingjie Song , Yize Chen , Zixu Zhang , Benyou Wang

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly…

Machine Learning · Computer Science 2025-09-17 Huajun Zhou , Fengtao Zhou , Jiabo Ma , Yingxue Xu , Xi Wang , Xiuming Zhang , Li Liang , Zhenhui Li , Hao Chen

Artificial intelligence and machine learning have shown great promise in their ability to accelerate novel materials discovery. As researchers and domain scientists seek to unify and consolidate chemical knowledge, the case for models with…

The rapid advancement of autonomous systems, including self-driving vehicles and drones, has intensified the need to forge true Spatial Intelligence from multi-modal onboard sensor data. While foundation models excel in single-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Song Wang , Lingdong Kong , Xiaolu Liu , Hao Shi , Wentong Li , Jianke Zhu , Steven C. H. Hoi

Recent advances in computational pathology and artificial intelligence have significantly enhanced the utilization of gigapixel whole-slide images and and additional modalities (e.g., genomics) for pathological diagnosis. Although deep…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Qichen Sun , Zhengrui Guo , Rui Peng , Hao Chen , Jinzhuo Wang

Building multisensory AI systems that learn from multiple sensory inputs such as text, speech, video, real-world sensors, wearable devices, and medical data holds great promise for impact in many scientific areas with practical benefits,…

Machine Learning · Computer Science 2024-05-01 Paul Pu Liang

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the…

We propose a pre-training strategy called Multi-modal Multi-task Masked Autoencoders (MultiMAE). It differs from standard Masked Autoencoding in two key aspects: I) it can optionally accept additional modalities of information in the input…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Roman Bachmann , David Mizrahi , Andrei Atanov , Amir Zamir

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Multimodal foundation models have shown compelling but conflicting performance in medical image interpretation. However, the mechanisms by which these models integrate and prioritize different data modalities, including images and text,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Thomas Buckley , James A. Diao , Pranav Rajpurkar , Adam Rodman , Arjun K. Manrai

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Multi-modal learning has achieved remarkable success by integrating information from various modalities, achieving superior performance in tasks like recognition and retrieval compared to uni-modal approaches. However, real-world scenarios…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Xiaohao Liu , Xiaobo Xia , Zhuo Huang , See-Kiong Ng , Tat-Seng Chua

Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

To effectively engage in human society, the ability to adapt, filter information, and make informed decisions in ever-changing situations is critical. As robots and intelligent agents become more integrated into human life, there is a…

Artificial Intelligence · Computer Science 2025-11-13 Mingyang Mao , Mariela M. Perez-Cabarcas , Utteja Kallakuri , Nicholas R. Waytowich , Xiaomin Lin , Tinoosh Mohsenin

Edge-based multimodal medical monitoring requires models that balance diagnostic accuracy with severe energy constraints. Continuous acquisition of ECG, PPG, EMG, and IMU streams rapidly drains wearable batteries, often limiting operation…

Emerging Technologies · Computer Science 2026-04-14 Chengwei Zhou , Zhaoyan Jia , Haotian Yu , Xuming Chen , Brandon Lee , Christopher Pulliam , Steve Majerus , Massoud Pedram , Gourav Datta

Medicine is inherently a multimodal discipline. Medical images can reflect the pathological changes of cancer and tumors, while the expression of specific genes can influence their morphological characteristics. However, most deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jiaying Zhou , Mingzhou Jiang , Junde Wu , Jiayuan Zhu , Ziyue Wang , Yueming Jin

To effectively exploit the potential of large-scale models, various pre-training strategies supported by massive data from different sources are proposed, including supervised pre-training, weakly-supervised pre-training, and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Weijie Su , Xizhou Zhu , Chenxin Tao , Lewei Lu , Bin Li , Gao Huang , Yu Qiao , Xiaogang Wang , Jie Zhou , Jifeng Dai