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Magnetic particle imaging (MPI) offers unparalleled contrast and resolution for tracing magnetic nanoparticles. A common imaging procedure calibrates a system matrix (SM) that is used to reconstruct data from subsequent scans. The ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Can Barış Top , Emine Ulku Saritas , Tolga Çukur

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool that provides excellent soft-tissue contrast without the use of ionizing radiation. Compared to other clinical imaging modalities (e.g., CT or ultrasound), however, the data…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Rizwan Ahmad , Charles A. Bouman , Gregery T. Buzzard , Stanley Chan , Sizhou Liu , Edward T. Reehorst , Philip Schniter

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

Purpose: To develop a general framework for Parallel Imaging (PI) with the use of Maxwell regularization for the estimation of the sensitivity maps (SMs) and constrained optimization for the parameter-free image reconstruction. Theory and…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Matteo Alessandro Francavilla , Stamatios Lefkimmiatis , Jorge F. Villena , Athanasios G. Polimeridis

Magnetic Particle Imaging (MPI) is an emerging imaging modality based on the magnetic response of superparamagnetic iron oxide nanoparticles to achieve high-resolution and real-time imaging without harmful radiation. One key challenge in…

Numerical Analysis · Mathematics 2025-01-13 Meira Iske , Hannes Albers , Tobias Knopp , Tobias Kluth

We contribute to the mathematical modeling and analysis of magnetic particle imaging which is a promising new in-vivo imaging modality. Concerning modeling, we develop a structured decomposition of the imaging process and extract its core…

Numerical Analysis · Mathematics 2016-05-27 Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) offers exceptional contrast for magnetic nanoparticles (MNP) at high spatio-temporal resolution. A common procedure in MPI starts with a calibration scan to measure the system matrix (SM), which is then used…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Emine Ulku Saritas , Can Barış Top , Tolga Çukur

The tomographic imaging method magnetic particle imaging (MPI) requires a multi-patch approach for capturing large field of views. This approach consists of a continuous or stepwise spatial shift of a small sub-volume of only few cubic…

Medical Physics · Physics 2022-05-03 Marija Boberg , Tobias Knopp , Patryk Szwargulski , Martin Möddel

Magnetic Particle Imaging (MPI) is a novel medical imaging modality. One of the established methods for MPI reconstruction is based on the System Matrix (SM). However, the calibration of the SM is often time-consuming and requires repeated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xuqing Geng , Lei Su , Zhongwei Bian , Zewen Sun , Jiaxuan Wen , Jie Tian , Yang Du

Various imaging modalities allow for time-dependent image reconstructions from measurements where its acquisition also has a time-dependent nature. Magnetic particle imaging (MPI) falls into this class of imaging modalities and it thus also…

Numerical Analysis · Mathematics 2023-06-21 Christina Brandt , Tobias Kluth , Tobias Knopp , Lena Westen

Magnetic particle imaging (MPI) is a tracer-based technique that directly detects the distribution of magnetic iron-oxide nanoparticles with millisecond temporal resolution and no tissue background. Despite extensive preclinical work,…

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas

Magnetic particle imaging (MPI) is a promising new in-vivo medical imaging modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response in an applied magnetic field. In this paper we provide a…

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

In Magnetic Particle Imaging (MPI), it is typically assumed that the studied specimen is stationary during the data acquisition. In practical applications however, the searched-for 3D distribution of the magnetic nanoparticles might show a…

Optimization and Control · Mathematics 2024-01-26 Marius Nitzsche , Bernadette N Hahn

Magnetic Particle Imaging (MPI) is a tomographic imaging modality capable of real-time, high-sensitivity mapping of superparamagnetic iron oxide nanoparticles. Model-based image reconstruction provides an alternative to conventional methods…

Parallel imaging is a widely-used technique to accelerate magnetic resonance imaging (MRI). However, current methods still perform poorly in reconstructing artifact-free MRI images from highly undersampled k-space data. Recently, implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-10-20 Ruimin Feng , Qing Wu , Yuyao Zhang , Hongjiang Wei

Magnetic particle imaging (MPI) is a tomographic method to determine the spatio-temporal distribution of magnetic nanoparticles. In this document, a file format for the standardized storage of MPI and magnetic particle spectroscopy (MPS)…

The main disadvantage of Magnetic Resonance Imaging (MRI) are its long scan times and, in consequence, its sensitivity to motion. Exploiting the complementary information from multiple receive coils, parallel imaging is able to recover…

Numerical Analysis · Computer Science 2017-03-07 Martin Uecker

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…