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Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

The protein design problem involves finding polypeptide sequences folding into a given threedimensional structure. Its rigorous algorithmic solution is computationally demanding, involving a nested search in sequence and structure spaces.…

Quantum Physics · Physics 2024-07-11 Veronica Panizza , Philipp Hauke , Cristian Micheletti , Pietro Faccioli

Recent advances in large language models (LLMs) and agent system designs have empowered agents with unprecedented levels of capability. However, existing agent benchmarks are showing a trend of rapid ceiling-hitting by newly developed…

Artificial Intelligence · Computer Science 2026-03-25 Dadi Guo , Tianyi Zhou , Dongrui Liu , Chen Qian , Qihan Ren , Shuai Shao , Zhiyuan Fan , Yi R. Fung , Kun Wang , Linfeng Zhang , Jing Shao

Current autonomic computing systems are ad hoc solutions that are designed and implemented from the scratch. When designing software, in most cases two or more patterns are to be composed to solve a bigger problem. A composite design…

Software Engineering · Computer Science 2012-09-11 Vishnuvardhan Mannava , T. Ramesh

Neural Architecture Search is a costly practice. The fact that a search space can span a vast number of design choices with each architecture evaluation taking nontrivial overhead makes it hard for an algorithm to sufficiently explore…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Keith G. Mills , Fred X. Han , Mohammad Salameh , Shengyao Lu , Chunhua Zhou , Jiao He , Fengyu Sun , Di Niu

Ensemble approaches for deep-learning-based semantic segmentation remain insufficiently explored despite the proliferation of competitive benchmarks and downstream applications. In this work, we explore and benchmark the popular ensembling…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Rawal Khirodkar , Brandon Smith , Siddhartha Chandra , Amit Agrawal , Antonio Criminisi

Over the past decade, machine learning model complexity has grown at an extraordinary rate, as has the scale of the systems training such large models. However there is an alarmingly low hardware utilization (5-20%) in large scale AI…

Hardware Architecture · Computer Science 2022-11-14 Newsha Ardalani , Saptadeep Pal , Puneet Gupta

Model predictive control (MPC) is a powerful strategy for planning and control in autonomous mobile robot navigation. However, ensuring safety in real-world deployments remains challenging due to the presence of disturbances and measurement…

Robotics · Computer Science 2025-08-12 Dennis Benders , Johannes Köhler , Robert Babuška , Javier Alonso-Mora , Laura Ferranti

As modern software systems expand in scale and complexity, the challenges associated with their modeling and formulation grow increasingly intricate. Traditional approaches often fall short in effectively addressing these complexities,…

Software Engineering · Computer Science 2025-05-20 Tarik Houichime , Younes El Amrani

Efficiently utilizing procured power and optimizing performance of scientific applications under power and energy constraints are challenging. The HPC PowerStack defines a software stack to manage power and energy of high-performance…

This paper explores the multi-access distributed computing (MADC) model, a novel distributed computing framework where mapper and reducer nodes are distinct entities. Unlike traditional MapReduce frameworks, MADC leverages coding-theoretic…

Information Theory · Computer Science 2025-08-08 Shanuja Sasi , Onur Günlü

Phase retrieval deals with the estimation of complex-valued signals solely from the magnitudes of linear measurements. While there has been a recent explosion in the development of phase retrieval algorithms, the lack of a common interface…

Optimization and Control · Mathematics 2017-12-01 Rohan Chandra , Ziyuan Zhong , Justin Hontz , Val McCulloch , Christoph Studer , Tom Goldstein

Deep neural networks are widely deployed in many fields. Due to the in-situ computation (known as processing in memory) capacity of the Resistive Random Access Memory (ReRAM) crossbar, ReRAM-based accelerator shows potential in accelerating…

Hardware Architecture · Computer Science 2024-03-11 Chenguang Zhang , Zhihang Yuan , Xingchen Li , Guangyu Sun

In several application domains, high-dimensional observations are collected and then analysed in search for naturally occurring data clusters which might provide further insights about the nature of the problem. In this paper we describe a…

Machine Learning · Statistics 2012-03-07 Brian McWilliams , Giovanni Montana

Power delivery network (PDN) design is a nontrivial, time-intensive, and iterative task. Correct PDN design must account for considerations related to power bumps, currents, blockages, and signal congestion distribution patterns. This work…

Hardware Architecture · Computer Science 2021-10-28 Vidya A. Chhabria , Sachin S. Sapatnekar

The rise of machine learning technology inspires a boom of its applications in electronic design automation (EDA) and helps improve the degree of automation in chip designs. However, manually crafted machine learning models require…

Recently, differentiable search methods have made major progress in reducing the computational costs of neural architecture search. However, these approaches often report lower accuracy in evaluating the searched architecture or…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Xin Chen , Lingxi Xie , Jun Wu , Qi Tian

CPU-FPGA heterogeneous architectures are attracting ever-increasing attention in an attempt to advance computational capabilities and energy efficiency in today's datacenters. These architectures provide programmers with the ability to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-24 Jason Cong , Peng Wei , Cody Hao Yu , Peng Zhang

This paper presents a framework that enables a systematic and rational choice of NMPC design components such as control updating period, down-sampling period for prediction, control parameterization, prediction horizon's length, the maximum…

Systems and Control · Electrical Eng. & Systems 2023-10-02 Mazen Alamir

We present a method and tool for evaluating the placement of Distributed Energy Resources (DER) on distribution circuits in order to control voltages and power flows. Our previous work described Phasor-Based Control (PBC), a novel control…

Systems and Control · Electrical Eng. & Systems 2021-03-24 Jaimie Swartz , Brittany Wais , Elizabeth Ratnam , Alexandra von Meier