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As the machine learning and systems communities strive to achieve higher energy-efficiency through custom deep neural network (DNN) accelerators, varied precision or quantization levels, and model compression techniques, there is a need for…

Hardware Architecture · Computer Science 2022-07-01 Ahmet Inci , Siri Garudanagiri Virupaksha , Aman Jain , Ting-Wu Chin , Venkata Vivek Thallam , Ruizhou Ding , Diana Marculescu

Designing novel protein sequences for a desired 3D topological fold is a fundamental yet non-trivial task in protein engineering. Challenges exist due to the complex sequence--fold relationship, as well as the difficulties to capture the…

Machine Learning · Computer Science 2021-06-25 Yue Cao , Payel Das , Vijil Chenthamarakshan , Pin-Yu Chen , Igor Melnyk , Yang Shen

Assembly-based tools provide a powerful modeling paradigm for non-expert shape designers. However, choosing a component from a large shape repository and aligning it to a partial assembly can become a daunting task. In this paper we…

Graphics · Computer Science 2018-07-05 Minhyuk Sung , Hao Su , Vladimir G. Kim , Siddhartha Chaudhuri , Leonidas Guibas

We propose a Path-Tracking Hybrid A* planner coupled with a hierarchical Model Predictive Control (MPC) framework for path smoothing in agricultural vehicles. The goal is to minimize deviation from reference paths during cross-furrow…

Robotics · Computer Science 2025-05-20 Mingke Lu , Han Gao , Haijie Dai , Qianli Lei , Chang Liu

The design of compact deep neural networks is a crucial task to enable widespread adoption of deep neural networks in the real-world, particularly for edge and mobile scenarios. Due to the time-consuming and challenging nature of manually…

Neural and Evolutionary Computing · Computer Science 2019-10-16 Mohammad Javad Shafiee , Andrew Hryniowski , Francis Li , Zhong Qiu Lin , Alexander Wong

Motivation: RNA design aims to find RNA sequences that fold into a given target secondary structure, a problem also known as RNA inverse folding. However, not all target structures are designable. Recent advances in RNA designability have…

Data Structures and Algorithms · Computer Science 2026-04-28 Tianshuo Zhou , David H. Mathews , Liang Huang

Basic block reordering is an important step for profile-guided binary optimization. The state-of-the-art goal for basic block reordering is to maximize the number of fall-through branches. However, we demonstrate that such orderings may…

Programming Languages · Computer Science 2020-04-14 Andy Newell , Sergey Pupyrev

Hardware-Software Co-Design is a highly successful strategy for improving performance of domain-specific computing systems. We argue for the application of the same methodology to deep learning; specifically, we propose to extend neural…

Machine Learning · Computer Science 2020-01-10 Andrew Anderson , Jing Su , Rozenn Dahyot , David Gregg

Despite the possibility to quickly compute reachable sets of large-scale linear systems, current methods are not yet widely applied by practitioners. The main reason for this is probably that current approaches are not push-button-capable…

Numerical Analysis · Mathematics 2024-02-23 Mark Wetzlinger , Niklas Kochdumper , Matthias Althoff

Autonomous vehicle platoons present near- and long-term opportunities to enhance operational efficiencies and save lives. The past 30 years have seen rapid development in the autonomous driving space, enabling new technologies that will…

Robotics · Computer Science 2024-10-16 Michael Shaham , Risha Ranjan , Engin Kirda , Taskin Padir

Test-time compute scaling allocates inference computation uniformly, uses fixed sampling strategies, and applies verification only for reranking. In contrast, we propose a verifier-guided adaptive framework treating reasoning as iterative…

Computation and Language · Computer Science 2026-04-08 Ahsan Bilal , Ahmed Mohsin , Muhammad Umer , Ali Subhan , Hassan Rizwan , Ayesha Mohsin , Dean Hougen

Molecular docking is a pivotal process in drug discovery. While traditional techniques rely on extensive sampling and simulation governed by physical principles, these methods are often slow and costly. The advent of deep learning-based…

Biomolecules · Quantitative Biology 2025-02-25 Kaiyuan Gao , Qizhi Pei , Gongbo Zhang , Jinhua Zhu , Kun He , Lijun Wu

Neural architectures and hardware accelerators have been two driving forces for the progress in deep learning. Previous works typically attempt to optimize hardware given a fixed model architecture or model architecture given fixed…

Engineering design research integrating artificial intelligence (AI) into computer-aided design (CAD) and computer-aided engineering (CAE) is actively being conducted. This study proposes a deep learning-based CAD/CAE framework in the…

Graphics · Computer Science 2022-10-04 Soyoung Yoo , Sunghee Lee , Seongsin Kim , Kwang Hyeon Hwang , Jong Ho Park , Namwoo Kang

Process mining offers techniques to exploit event data by providing insights and recommendations to improve business processes. The growing amount of algorithms for process discovery has raised the question of which algorithms perform best…

Software Engineering · Computer Science 2018-06-20 Toon Jouck , Alfredo Bolt , Benoît Depaire , Massimiliano de Leoni , Wil M. P. van der Aalst

Molecular design and synthesis planning are two critical steps in the process of molecular discovery that we propose to formulate as a single shared task of conditional synthetic pathway generation. We report an amortized approach to…

Machine Learning · Computer Science 2022-03-15 Wenhao Gao , Rocío Mercado , Connor W. Coley

The rapidly-changing deep learning landscape presents a unique opportunity for building inference accelerators optimized for specific datacenter-scale workloads. We propose Full-stack Accelerator Search Technique (FAST), a hardware…

Machine Learning · Computer Science 2022-02-02 Dan Zhang , Safeen Huda , Ebrahim Songhori , Kartik Prabhu , Quoc Le , Anna Goldie , Azalia Mirhoseini

In most real-world applications of artificial intelligence, the distributions of the data and the goals of the learners tend to change over time. The Probably Approximately Correct (PAC) learning framework, which underpins most machine…

Machine Learning · Computer Science 2025-11-13 Yuxin Bai , Cecelia Shuai , Ashwin De Silva , Siyu Yu , Pratik Chaudhari , Joshua T. Vogelstein

Pattern database (PDB) is one of the most popular automated heuristic generation techniques. A PDB maps states in a planning task to abstract states by considering a subset of variables and stores their optimal costs to the abstract goal in…

Artificial Intelligence · Computer Science 2024-10-15 Yufeng Zou

Optimizing scientific applications to take full advan-tage of modern memory subsystems is a continual challenge forapplication and compiler developers. Factors beyond working setsize affect performance. A benchmark framework that…

Performance · Computer Science 2018-12-20 Mahesh Lakshminarasimhan , Catherine Olschanowsky
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