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I develop a new identification strategy for treatment effects when noisy measurements of unobserved confounding factors are available. I use proxy variables to construct a random variable conditional on which treatment variables become…

Econometrics · Economics 2022-09-30 Kenichi Nagasawa

Amortized variational inference in latent-variable forecasters creates a deployment gap: the test-time encoder approximates a training-time optimization-refined latent, but without access to future targets. This gap introduces unnecessary…

Machine Learning · Computer Science 2026-02-17 Abhijit Gupta

Accurately estimating the proportion of true signals among a large number of variables is crucial for enhancing the precision and reliability of scientific research. Traditional signal proportion estimators often assume independence among…

Statistics Theory · Mathematics 2026-05-15 Jingtian Bai , Xinge Jessie Jeng

Unmeasured confounding, unethical exposure, and ill-defined interventions pose significant challenges to evaluating policy-relevant mediation estimands in medicine and public health. In observational studies involving harmful exposures, the…

Methodology · Statistics 2026-05-12 Yang Bai , Yifan Cui , Baoluo Sun

To effectively study complex causal systems, it is often useful to construct abstractions of parts of the system by discarding irrelevant details while preserving key features. The Information Bottleneck (IB) method is a widely used…

Machine Learning · Computer Science 2025-06-12 Francisco N. F. Q. Simoes , Mehdi Dastani , Thijs van Ommen

An algorithm based on PLS regression has been developed and optimized for measuring blood glucose level using the infra-red transmission spectrum of blood samples. A set of blood samples were tagged with their glucose concentration using an…

Quantitative Methods · Quantitative Biology 2018-04-11 Afarin Aghassizadeh , Mohammad Reza Nematollahi , Iman Mirzaie , Mehdi Fardmanesh

The conventional method of glucose measurement such as pricking blood from the body is prevalent which brings pain and trauma. Invasive methods of measurement sometimes raise the risk of blood infection to the patient. Sometimes, some of…

Medical Physics · Physics 2023-08-24 Prateek Jain , Amit Joshi , Saraju Mohanty

Self-monitoring of blood glucose (SMBG) and continuous glucose monitoring (CGM) are commonly used by type 1 diabetes (T1D) patients to measure glucose concentrations. The proposed adaptive basal-bolus algorithm (ABBA) supports inputs from…

Systems and Control · Electrical Eng. & Systems 2024-12-20 Qingnan Sun , Marko V. Jankovic , João Budzinski , Brett Moore , Peter Diem , Christoph Stettler , Stavroula G. Mougiakakou

This paper aims to examine the use of sparse methods to forecast the real, in the chain-linked volume sense, expenditure components of the US and EU GDP in the short-run sooner than the national institutions of statistics officially release…

Econometrics · Economics 2020-10-29 Saulius Jokubaitis , Dmitrij Celov , Remigijus Leipus

Data-driven societal event forecasting methods exploit relevant historical information to predict future events. These methods rely on historical labeled data and cannot accurately predict events when data are limited or of poor quality.…

Machine Learning · Computer Science 2021-12-13 Songgaojun Deng , Huzefa Rangwala , Yue Ning

Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be…

Nonlinear causal effects are prevalent in many research scenarios involving continuous exposures, and instrumental variables (IVs) can be employed to investigate such effects, particularly in the presence of unmeasured confounders. However,…

Methodology · Statistics 2025-10-29 Haodong Tian , Ashish Patel , Stephen Burgess

Diabetes encompasses a complex landscape of glycemic control that varies widely among individuals. However, current methods do not faithfully capture this variability at the meal level. On the one hand, expert-crafted features lack the…

Machine Learning · Computer Science 2023-12-07 Ke Alexander Wang , Emily B. Fox

In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

Methodology · Statistics 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

Empirical researchers are often interested in not only whether a treatment affects an outcome of interest, but also how the treatment effect arises. Causal mediation analysis provides a formal framework to identify causal mechanisms through…

Econometrics · Economics 2022-02-01 Bora Kim

Statistical inference on the explained variation of an outcome by a set of covariates is of particular interest in practice. When the covariates are of moderate to high-dimension and the effects are not sparse, several approaches have been…

Methodology · Statistics 2022-01-24 Hua Yun Chen

Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV…

Methodology · Statistics 2025-09-23 Zhonghua Liu , Baoluo Sun , Ting Ye , David Richardson , Eric Tchetgen Tchetgen

The abundance of modern health data provides many opportunities for the use of machine learning techniques to build better statistical models to improve clinical decision making. Predicting time-to-event distributions, also known as…

Machine Learning · Statistics 2020-12-15 Zidi Xiu , Chenyang Tao , Benjamin A. Goldstein , Ricardo Henao

Diffusion models have gained attention for their ability to represent complex distributions and incorporate uncertainty, making them ideal for robust predictions in the presence of noisy or incomplete data. In this study, we develop and…

Machine Learning · Computer Science 2024-11-05 Yilin Zhuang , Sibo Cheng , Karthik Duraisamy

Coastal flooding poses increasing threats to communities worldwide, necessitating accurate and hyper-local inundation forecasting for effective emergency response. However, real-world deployment of forecasting systems is often constrained…

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