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Driving a system from one state to another through targeted interventions is a fundamental challenge in science, yet most predictive models offer limited mechanistic insight and no principled framework for decision-making. Here we present…

Machine Learning · Computer Science 2026-05-29 Zixuan Song , Uwe Mueller , Dimitris V. Manatakis

A wide variety of real life complex networks are prohibitively large for modeling, analysis and control. Understanding the structure and dynamics of such networks entails creating a smaller representative network that preserves its relevant…

We demonstrate that the algorithmic information content of a system is deeply connected to its potential dynamics, thus affording an avenue for moving systems in the information-theoretic space and controlling them in the phase space. To…

Other Quantitative Biology · Quantitative Biology 2018-04-06 Hector Zenil , Narsis A. Kiani , Francesco Marabita , Yue Deng , Szabolcs Elias , Angelika Schmidt , Gordon Ball , Jesper Tegnér

We consider the decision-making framework of online convex optimization with a very large number of experts. This setting is ubiquitous in contextual and reinforcement learning problems, where the size of the policy class renders…

Machine Learning · Computer Science 2021-02-19 Elad Hazan , Karan Singh

In modern business modeling and analytics, data monitoring plays a critical role. Nowadays, sophisticated models often rely on hundreds or even thousands of input variables. Over time, structural changes such as abrupt level shifts or trend…

Methodology · Statistics 2019-10-07 Yingbo Li , Robert Cezeaux , Di Yu

Real-world reinforcement learning often faces environment drift, but most existing methods rely on static entropy coefficients/target entropy, causing over-exploration during stable periods and under-exploration after drift, and leaving…

Machine Learning · Computer Science 2026-05-19 Tongxi Wang , Zhuoyang Xia , Xinran Chen , Shan Liu

Supervised machine learning often operates on the data-driven paradigm, wherein internal model parameters are autonomously optimized to converge predicted outputs with the ground truth, devoid of explicitly programming rules or a priori…

Machine Learning · Computer Science 2024-12-12 Daniel Geissler , Bo Zhou , Mengxi Liu , Paul Lukowicz

Boosting is a method for learning a single accurate predictor by linearly combining a set of less accurate weak learners. Recently, structured learning has found many applications in computer vision. Inspired by structured support vector…

Machine Learning · Computer Science 2020-03-10 Chunhua Shen , Guosheng Lin , Anton van den Hengel

Catastrophic regime shifts in complex natural systems may be averted through advanced detection. Recent work has provided a proof-of-principle that many systems approaching a catastrophic transition may be identified through the lens of…

Other Quantitative Biology · Quantitative Biology 2012-04-30 Carl Boettiger , Alan Hastings

Causal discovery for dynamical systems poses a major challenge in fields where active interventions are infeasible. Most methods used to investigate these systems and their associated benchmarks are tailored to deterministic,…

Machine Learning · Computer Science 2025-10-13 Benjamin Herdeanu , Juan Nathaniel , Carla Roesch , Jatan Buch , Gregor Ramien , Johannes Haux , Pierre Gentine

High dimensional piecewise stationary graphical models represent a versatile class for modelling time varying networks arising in diverse application areas, including biology, economics, and social sciences. There has been recent work in…

Machine Learning · Statistics 2018-06-21 Hossein Keshavarz , George Michailidis , Yves Atchade

Prediction of new drug-target interactions is extremely important as it can lead the researchers to find new uses for old drugs and to realize the therapeutic profiles or side effects thereof. However, experimental prediction of drug-target…

Computational Engineering, Finance, and Science · Computer Science 2017-07-05 Farshid Rayhan , Sajid Ahmed , Swakkhar Shatabda , Dewan Md Farid , Zaynab Mousavian , Abdollah Dehzangi , M Sohel Rahman

Many real-life dynamical systems change abruptly followed by almost stationary periods. In this paper, we consider streams of data with such abrupt behavior and investigate the problem of tracking their statistical properties in an online…

Methodology · Statistics 2019-01-16 Hugo Lewi Hammer , Anis Yazidi

This paper establishes a precise high-dimensional asymptotic theory for boosting on separable data, taking statistical and computational perspectives. We consider a high-dimensional setting where the number of features (weak learners) $p$…

Statistics Theory · Mathematics 2022-11-21 Tengyuan Liang , Pragya Sur

Noise-induced phase transitions are common in various complex systems, from physics to biology. In this article, we investigate the emergence of crucial events in noise-induced phase transition processes and their potential significance for…

Data Analysis, Statistics and Probability · Physics 2023-06-28 Jacob D. Baxley , David R. Lambert , Mauro Bologna , Bruce J. West , Paolo Grigolini

A key challenge in systems biology is the elucidation of the underlying principles, or fundamental laws, which determine the cellular phenotype. Understanding how these fundamental principles are altered in diseases like cancer is important…

Molecular Networks · Quantitative Biology 2014-08-06 Andrew Teschendorff , Peter Sollich , Reimer Kuehn

Identification of causal structures and quantification of direct information flows in complex systems is a challenging yet important task, with practical applications in many fields. Data generated by dynamical processes or large-scale…

Data Analysis, Statistics and Probability · Physics 2015-08-06 Carlo Cafaro , Warren M. Lord , Jie Sun , Erik M. Bollt

Inferring the structure and dynamics of network models is critical to understanding the functionality and control of complex systems, such as metabolic and regulatory biological networks. The increasing quality and quantity of experimental…

Dynamical Systems · Mathematics 2016-05-27 Niall M. Mangan , Steven L. Brunton , Joshua L. Proctor , J. Nathan Kutz

We introduce a comprehensive data-driven framework aimed at enhancing the modeling of physical systems, employing inference techniques and machine learning enhancements. As a demonstrative application, we pursue the modeling of cathodic…

Computational Physics · Physics 2025-02-04 Christian Jacobsen , Jiayuan Dong , Mehdi Khalloufi , Xun Huan , Karthik Duraisamy , Maryam Akram , Wanjiao Liu

Often the underlying system of differential equations driving a stochastic dynamical system is assumed to be known, with inference conditioned on this assumption. We present a Bayesian framework for discovering this system of differential…

Methodology · Statistics 2021-01-13 Kushagra Gupta , Dootika Vats , Snigdhansu Chatterjee