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Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

Background: Cognitive impairment in multiple sclerosis (MS) is driven by both focal inflammation and compartmentalized neurodegeneration, yet the relative effect of lesion-independent thalamic atrophy on information processing speed (IPS)…

Neurons and Cognition · Quantitative Biology 2026-02-19 Arshya Pooladi-Darvish , Heather Rosehart , Marina R. Everest , Ali R. Khan , Sarah A. Morrow

Accurate brain tumor diagnosis relies on the assessment of multiple Magnetic Resonance Imaging (MRI) sequences. However, in clinical practice, the acquisition of certain sequences may be affected by factors like motion artifacts or contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Saumya Gupta , Annie Singh , Chao Chen , Gagandeep Singh , Prateek Prasanna

Nuclei Segmentation from histology images is a fundamental task in digital pathology analysis. However, deep-learning-based nuclei segmentation methods often suffer from limited annotations. This paper proposes a realistic data augmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Yi Lin , Zeyu Wang , Kwang-Ting Cheng , Hao Chen

Ultrahigh field (UHF) Magnetic Resonance Imaging (MRI) provides a higher signal-to-noise ratio and, thereby, higher spatial resolution. However, UHF MRI introduces challenges such as transmit radiofrequency (RF) field (B1+) inhomogeneities,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Zhengyi Lu , Hao Liang , Xiao Wang , Xinqiang Yan , Yuankai Huo

The colorectal polyps classification is a critical clinical examination. To improve the classification accuracy, most computer-aided diagnosis algorithms recognize colorectal polyps by adopting Narrow-Band Imaging (NBI). However, the NBI…

Computer Vision and Pattern Recognition · Computer Science 2022-06-27 Weijie Ma , Ye Zhu , Ruimao Zhang , Jie Yang , Yiwen Hu , Zhen Li , Li Xiang

Whole heart segmentation (WHS) supports cardiovascular disease (CVD) diagnosis, disease monitoring, treatment planning, and prognosis. Deep learning has become the most widely used method for WHS applications in recent years. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Chenyu Zhang , Wenxue Guan , Xiaodan Xing , Guang Yang

Researchers have shown significant correlations among segmented objects in various medical imaging modalities and disease related pathologies. Several studies showed that using hand crafted features for disease prediction neglects the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Fahim Ahmed Zaman , Wahidul Alam , Tarun Kanti Roy , Amanda Chang , Kan Liu , Xiaodong Wu

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel

The presence of tertiary lymphoid structures (TLSs) on pancreatic pathological images is an important prognostic indicator of pancreatic tumors. Therefore, TLSs detection on pancreatic pathological images plays a crucial role in diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Bingxue Wang , Liwen Zou , Jun Chen , Yingying Cao , Zhenghua Cai , Yudong Qiu , Liang Mao , Zhongqiu Wang , Jingya Chen , Luying Gui , Xiaoping Yang

Purpose: The purpose of this study is to investigate the robustness of a commonly-used convolutional neural network for image segmentation with respect to visually-subtle adversarial perturbations, and suggest new methods to make these…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Zheng Liu , Jinnian Zhang , Varun Jog , Po-Ling Loh , Alan B McMillan

Purpose: Thoracic radiographs are commonly used to evaluate patients with confirmed or suspected thoracic pathology. Proper patient positioning is more challenging in canine and feline radiography than in humans due to less patient…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Peyman Tahghighi , Nicole Norena , Eran Ukwatta , Ryan B Appleby , Amin Komeili

The variability introduced by differences in MRI scanner models, acquisition protocols, and imaging sites hinders consistent analysis and generalizability across multicenter studies. We present a novel image-based harmonization framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Luca Caldera , Lara Cavinato , Francesca Ieva

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour

Ultra-high resolution 7 tesla (7T) magnetic resonance imaging (MRI) provides detailed anatomical views, offering better signal-to-noise ratio, resolution and tissue contrast than 3T MRI, though at the cost of accessibility. We present an…

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Accurate segmentation of tubular structures in medical images, such as vessels and airway trees, is crucial for computer-aided diagnosis, radiotherapy, and surgical planning. However, significant challenges exist in algorithm design when…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Yi Huang , Ke Zhang , Wei Liu , Yuanyuan Wang , Vishal M. Patel , Le Lu , Xu Han , Dakai Jin , Ke Yan

Retinal vessel segmentation is crucial for intelligent ophthalmic diagnosis, yet it faces three major challenges: insufficient multi-scale feature fusion, disruption of contextual continuity, and noise interference. This study proposes a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xinran Xu , Yuliang Ma , Sifu Cai , Ming Meng , Qiang Lv , Ruoyan Shi

The medical image is characterized by the inter-class indistinction, high variability, and noise, where the recognition of pixels is challenging. Unlike previous self-attention based methods that capture context information from one level,…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Fei Ding , Gang Yang , Jinlu Liu , Jun Wu , Dayong Ding , Jie Xv , Gangwei Cheng , Xirong Li