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We introduce a scalable witness-based persistent homology pipeline for full-brain MRI volumes that couples density-aware landmark selection with a GPU-ready witness filtration. Candidates are scored by a hybrid metric that balances…

Computational Geometry · Computer Science 2025-10-07 Jorge Leonardo Ruiz Williams

Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Md. Mehedi Hassan , Shafqat Alam , Shahriar Ahmed Seam , Maruf Ahmed

Automatic and consistent meningioma segmentation in T1-weighted MRI volumes and corresponding volumetric assessment is of use for diagnosis, treatment planning, and tumor growth evaluation. In this paper, we optimized the segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 David Bouget , André Pedersen , Sayied Abdol Mohieb Hosainey , Johanna Vanel , Ole Solheim , Ingerid Reinertsen

Accurate segmentation of punctate white matter lesion (PWML) in infantile brains by an automatic algorithm can reduce the potential risk of postnatal development. How to segment PWML effectively has become one of the active topics in…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Yalong Liu , Jie Li , Ying Wang , Miaomiao Wang , Xianjun Li , Zhicheng Jiao , Jian Yang , Xingbo Gao

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

White Matter Hyperintensity (WMH) is an imaging feature related to various diseases such as dementia and stroke. Accurately segmenting WMH using computer technology is crucial for early disease diagnosis. However, this task remains…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Changlu Guo

Automated segmentation of Pancreatic Ductal Adenocarcinoma (PDAC) from MRI is critical for clinical workflows but is hindered by poor tumor-tissue contrast and a scarcity of annotated data. This paper details our submission to the PANTHER…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Omer Faruk Durugol , Maximilian Rokuss , Yannick Kirchhoff , Klaus H. Maier-Hein

The continuous development of the photovoltaic (PV) industry has raised high requirements for the quality of monocrystalline of PV module cells. When learning to segment defect regions in PV module cell images, Tiny Hidden Cracks (THC) lead…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Jianye Yi , Xiaopin Zhong , Weixiang Liu , Zongze Wu , Yuanlong Deng , Zhengguang Wu

Autonomous neutron spectroscopy must solve three distinct tasks: detection (where is the signal?), inference (which Hamiltonian governs it?), and refinement (what are the parameters?). No single controller solves all three equally well. We…

Materials Science · Physics 2026-04-28 William Ratcliff

Medical Image Synthesis (MIS) plays an important role in the intelligent medical field, which greatly saves the economic and time costs of medical diagnosis. However, due to the complexity of medical images and similar characteristics of…

Image and Video Processing · Electrical Eng. & Systems 2025-03-07 Zhihan Ju , Wanting Zhou , Longteng Kong , Yu Chen , Yi Li , Zhenan Sun , Caifeng Shan

Medical image segmentation is almost the most important pre-processing procedure in computer-aided diagnosis but is also a very challenging task due to the complex shapes of segments and various artifacts caused by medical imaging, (i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Hao Du , Qihua Dong , Yan Xu , Jing Liao

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

In accelerated MRI reconstruction, the anatomy of a patient is recovered from a set of under-sampled and noisy measurements. Deep learning approaches have been proven to be successful in solving this ill-posed inverse problem and are…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Imaging biomarkers in magnetic resonance imaging (MRI) are important tools for diagnosing, tracking and treating Alzheimer's disease (AD). Neurofibrillary tau pathology in AD is closely linked to neurodegeneration and generally follows a…

Computational models that predict cellular phenotypic responses to chemical and genetic perturbations can accelerate drug discovery by prioritizing therapeutic hypotheses and reducing costly wet-lab iteration. However, extracting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Pin-Jui Huang , Yu-Hsuan Liao , SooHeon Kim , NoSeong Park , JongBae Park , DongMyung Shin

Automatic tumor segmentation of breast ultrasound (BUS) image is quite challenging due to the complicated anatomic structure of breast and poor image quality. Most tumor segmentation approaches achieve good performance on BUS images…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Fei Xu , Min Xian , Yingtao Zhang , Kuan Huang , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Magnetic Particle Imaging (MPI) is a promising imaging modality that tracks magnetic nanoparticles (MNPs) to generate real time, high-resolution images. However, achieving an optimal balance between strong signal strength and sharp image…

Medical Physics · Physics 2025-12-18 Abuobaida M. khair , Wenjing Jiang , Moritz Wildgruber , Wenjun Xi , Xiaopeng Ma