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Confocal microscopy in combination with real-space particle tracking has proven to be a powerful tool in scientific fields such as soft matter physics, materials science and cell biology. However, 3D tracking of anisotropic particles in…

Soft Condensed Matter · Physics 2015-05-20 T. H. Besseling , M. Hermes , A. Kuijk , B. de Nijs , T. -S. Deng , M. Dijkstra , A. Imhof , A. van Blaaderen

We present recent advances in the instrumentation and analysis methods for quantitative imaging of concentrated colloidal suspensions under flow. After a brief review of colloidal imaging, we describe various flow geometries for two and and…

Soft Condensed Matter · Physics 2009-09-29 Lucio Isa , Rut Besseling , Eric R. Weeks , Wilson C. K. Poon

High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…

Fluid Dynamics · Physics 2025-11-03 Elena Erben , Ivan Saraev , Weida Liao , Fan Nan , Eric Lauga , Moritz Kreysing

We demonstrate a three-dimensional (3D) optical diffraction tomographic technique with optimal frequency combination (OFC-ODT) for the 3D quantitative phase imaging of unlabeled specimens. Three sets of through-focus intensity images are…

Optics · Physics 2018-03-06 Jiaji Li , Qian Chen Jiasong Sun , Jialin Zhang , Junyi Ding , Chao Zuo

Suspensions of micro and nano particles made of Polystyrene, Poly(methyl methacrylate), Silicon dioxide etc. have been a standard model system to understand colloidal physics. . These systems have proved useful insights into phenomena such…

Soft Condensed Matter · Physics 2017-10-04 Praneet Prakash , Manoj Varma

We present a comprehensive study of cross-flow ultrafiltration (UF) of charge-stabilized suspensions, under low-salinity conditions of electrostatically strongly repelling colloidal particles. The axially varying permeate flux,…

Light-field microscopy (LFM) enables single-shot capture of multi-angular information from biological samples, supporting real-time volumetric imaging. However, traditional physics-based algorithms often suffer from limited spatial…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Qihong Zhao , Shaokang Yan , Zhimin Qiao , Jinjia Wang , Bo Xiong

Confocal microscopy of fluorescent labeled particles has been used to study the dynamical and structural properties of colloidal and granular matter in real space. Localization algorithms allow for a fully automatized determination of the…

Soft Condensed Matter · Physics 2011-12-08 Marcel Roth , Michael Franzmann , Maria D'Acunzi , Max Kreiter , Günter K. Auernhammer

We demonstrate optical trapping and manipulation of defects and transparent microspheres in nematic liquid crystals (LCs). The three-dimensional director fields and positions of the particles are visualized using the Fluorescence Confocal…

The reconfiguration of soft, deformable particles upon adsorption at the interface between two fluids underpins many aspects of their dynamics and interactions, ultimately controlling the macroscopic properties of particle monolayers of…

Soft Condensed Matter · Physics 2022-04-21 Jacopo Vialetto , Shivaprakash N. Ramakrishna , Lucio Isa

Particle size is a key variable in understanding the behaviour of the particulate products that underpin much of our modern lives. Typically obtained from suspensions at rest, measuring the particle size under flowing conditions would…

Soft Condensed Matter · Physics 2021-07-22 James A Richards , Vincent A Martinez , Jochen Arlt

In this paper we present a method to robustly evaluate the quantitative accuracy of various tomographic phase microscopy (TPM) methods with a multiple scattering 3D-printed microphantom with known geometry and refractive index distribution.…

Existing 3D mask learning methods encounter performance bottlenecks under limited data, and our objective is to overcome this limitation. In this paper, we introduce a triple point masking scheme, named TPM, which serves as a scalable…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Jiaming Liu , Linghe Kong , Yue Wu , Maoguo Gong , Hao Li , Qiguang Miao , Wenping Ma , Can Qin

Particle tracking is a key to single-particle-level confocal microscopy observation of colloidal suspensions, emulsions, and granular matter. The conventional tracking method has not been able to provide accurate information on the size of…

Soft Condensed Matter · Physics 2013-01-31 Mathieu Leocmach , Hajime Tanaka

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

The Discrete Particle Method (DPM) is used to model granular flows down an inclined chute. We observe three major regimes: static piles, steady uniform flows and accelerating flows. For flows over a smooth base, other (quasi-steady) regimes…

Soft Condensed Matter · Physics 2011-08-26 Thomas Weinhart , Anthony Thornton , Stefan Luding , Onno Bokhove

Droplet microfluidics combined with optical detection has become a powerful approach for high-throughput single-cell assays, but these systems often face limited sensitivity and signal heterogeneity due to optical and geometrical…

Fluid Dynamics · Physics 2026-03-05 Kanimozhi Kumaresan , Thaipally Sujith , Anil Prabhakar , Ashis Kumar Sen

High-throughput label-free measurements of the optical and mechanical properties of single microparticles play an important role in biological research, drug development, and related large population assays. Mechanical detection techniques…

Instrumentation and Detectors · Physics 2018-12-05 Kewen Han , Jeewon Suh , Gaurav Bahl

Flow linear dichroism is a biophysical spectroscopic technique that exploits the shear-induced alignment of elongated particles in suspension. Motivated by the broad aim of optimising the sensitivity of this technique, and more specifically…

Fluid Dynamics · Physics 2019-04-03 G. Cupples , D. J. Smith , M. R. Hicks , R. J. Dyson

We investigate the angle of repose ${\theta}_r$ of dense suspensions of colloidal silica particles ($d = 2$ $\mu m$ to $7$ $\mu m$) in water-filled microfluidic rotating drums experiments, to probe the crossover between the thermal…

Soft Condensed Matter · Physics 2026-04-15 Jesús Fernández , Loïc Vanel , Antoine Bérut
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