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The increasing use of Machine Learning (ML) in sensitive domains such as healthcare, finance, and public policy has raised concerns about the transparency of automated decisions. Explainable AI (XAI) addresses this by clarifying how models…

Artificial Intelligence · Computer Science 2026-02-13 Natalia Abarca , Andrés Carvallo , Claudia López Moncada , Felipe Bravo-Marquez

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Deriving personalized insights from popular wearable trackers requires complex numerical reasoning that challenges standard LLMs, necessitating tool-based approaches like code generation. Large language model (LLM) agents present a…

With advances in large language models (LLMs), researchers are creating new systems that can perform AI-driven analytics over large unstructured datasets. Recent work has explored executing such analytics queries using semantic operators --…

Artificial Intelligence · Computer Science 2025-09-04 Matthew Russo , Tim Kraska

Human-AI interfaces play a pivotal role in integrating clinicians' expertise with artificial intelligence to enhance both healthcare practice and research. However, designing effective interfaces in this domain remains a significant…

Human-Computer Interaction · Computer Science 2026-01-21 Rui Sheng , Chuhan Shi , Sobhan Lotfi , Shiyi Liu , Adam Perer , Huamin Qu , Furui Cheng

Large language model (LLM)-based AI agents are increasingly capable of complex clinical reasoning and may soon participate in medical decision-making with limited or no real-time human oversight. This shift raises fundamental questions…

Computers and Society · Computer Science 2026-03-17 Tom Bisson , Henriette Voelker , Sanddhya Jayabalan , A John Iafrate , Jakob N Kather , Jochen K Lennerz

Explainable AI (XAI) aims to improve user understanding and decisions when using AI models. However, despite innovations in XAI, recent user evaluations reveal that this goal remains elusive. Understanding human cognition can help explain…

Artificial Intelligence · Computer Science 2026-05-01 Louth Bin Rawshan , Zhuoyu Wang , Brian Y. Lim

Patients have distinct information needs about their hospitalization that can be addressed using clinical evidence from electronic health records (EHRs). While artificial intelligence (AI) systems show promise in meeting these needs, robust…

Computation and Language · Computer Science 2026-03-31 Sarvesh Soni , Dina Demner-Fushman

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

Natural language inference (NLI) is critical for complex decision-making in biomedical domain. One key question, for example, is whether a given biomedical mechanism is supported by experimental evidence. This can be seen as an NLI problem…

Computation and Language · Computer Science 2022-10-27 Mohaddeseh Bastan , Mihai Surdeanu , Niranjan Balasubramanian

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

This paper reports a case study on how explainability requirements were elicited during the development of an AI system for predicting cerebral palsy (CP) risk in infants. Over 18 months, we followed a development team and hospital…

Software Engineering · Computer Science 2026-01-06 Tor Sporsem , Stine Rasdal Finserås , Lars Adde , Inga Strümke

As AI becomes fundamental in sectors like healthcare, explainable AI (XAI) tools are essential for trust and transparency. However, traditional user studies used to evaluate these tools are often costly, time consuming, and difficult to…

Artificial Intelligence · Computer Science 2024-10-24 Francesco Bombassei De Bona , Gabriele Dominici , Tim Miller , Marc Langheinrich , Martin Gjoreski

AI-powered LizAI XT ensures real-time and accurate mega-structure of different clinical datasets and largely inaccessible and fragmented sources, into one comprehensive table or any designated forms, based on diseases, clinical variables,…

Computers and Society · Computer Science 2025-05-19 Trung Tin Nguyen , Salomon M. Stemmer , David R. Elmaleh

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Much previous AI research has focused on developing monolithic models to maximize their intelligence, with the primary goal of enhancing performance on specific tasks. In contrast, this work attempts to study using LLM-based agents to…

Computation and Language · Computer Science 2026-02-10 Xiangyuan Xue , Zeyu Lu , Di Huang , Zidong Wang , Wanli Ouyang , Lei Bai

Systematic reviews are essential for evidence-based medicine, but reviewing 1.5 million+ annual publications manually is infeasible. Current AI approaches suffer from hallucinations in systematic review tasks, with studies reporting rates…

Artificial Intelligence · Computer Science 2026-01-07 Duc Ngo , Arya Rahgoza

Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation…

Machine Learning · Computer Science 2022-12-09 Weina Jin , Xiaoxiao Li , Mostafa Fatehi , Ghassan Hamarneh

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Although there has been a growing interest among industries in integrating generative LLMs into their services, limited experience and scarcity of resources act as a barrier in launching and servicing large-scale LLM-based services. In this…

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