English
Related papers

Related papers: ChemCrow: Augmenting large-language models with ch…

200 papers

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

As the capabilities of large language models (LLMs) continue to advance, evaluating their performance becomes increasingly crucial and challenging. This paper aims to bridge this gap by introducing CMMLU, a comprehensive Chinese benchmark…

Computation and Language · Computer Science 2024-01-19 Haonan Li , Yixuan Zhang , Fajri Koto , Yifei Yang , Hai Zhao , Yeyun Gong , Nan Duan , Timothy Baldwin

Music Information Retrieval (MIR) encompasses a broad range of computational techniques for analyzing and understanding musical content, with recent deep learning advances driving substantial improvements. Building upon these advances, this…

Sound · Computer Science 2025-09-24 Chih-Cheng Chang , Bo-Yu Chen , Lu-Rong Chen , Li Su

In recent years, conventional chemistry techniques have faced significant challenges due to their inherent limitations, struggling to cope with the increasing complexity and volume of data generated in contemporary research endeavors.…

Identifying reliable synthesis pathways in materials chemistry is a complex task, particularly in polymer science, due to the intricate and often non-unique nomenclature of macromolecules. To address this challenge, we propose an agent…

Artificial Intelligence · Computer Science 2025-04-16 Qinyu Ma , Yuhao Zhou , Jianfeng Li

Recent improvements in large language models (LLMs) have had a dramatic effect on capabilities and productivity across many disciplines involving critical thinking and writing. The development of the model context protocol (MCP) provides a…

Accurate molecular property prediction is a critical challenge with wide-ranging applications in chemistry, materials science, and drug discovery. Molecular representation methods, including fingerprints and graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-08-13 Jiaxin Ju , Yizhen Zheng , Huan Yee Koh , Can Wang , Shirui Pan

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

Large Language Models (LLMs) have demonstrated proficiency in addressing tasks that necessitate a combination of task planning and the usage of external tools that require a blend of task planning and the utilization of external tools, such…

Artificial Intelligence · Computer Science 2023-11-21 Yilun Kong , Jingqing Ruan , Yihong Chen , Bin Zhang , Tianpeng Bao , Shiwei Shi , Guoqing Du , Xiaoru Hu , Hangyu Mao , Ziyue Li , Xingyu Zeng , Rui Zhao

Machine learning (ML) is increasingly becoming a common tool in computational chemistry. At the same time, the rapid development of ML methods requires a flexible software framework for designing custom workflows. MLatom 3 is a program…

This paper presents an in-depth analysis of the performance of seven different Large Language Models (LLMs) in solving a diverse set of math advanced calculus problems. The study aims to evaluate these models' accuracy, reliability, and…

Computation and Language · Computer Science 2025-03-07 In Hak Moon

Multimodal Large Language Models (MLLMs) have seen growing adoption across various scientific disciplines. These advancements encourage the investigation of molecule-text modeling within synthetic chemistry, a field dedicated to designing…

Machine Learning · Computer Science 2024-06-21 He Cao , Yanjun Shao , Zhiyuan Liu , Zijing Liu , Xiangru Tang , Yuan Yao , Yu Li

Large Language Models (LLMs) have shown promise in natural language processing tasks, with the potential to automate systematic reviews. This study evaluates the performance of three state-of-the-art LLMs in conducting systematic review…

Information Retrieval · Computer Science 2025-02-25 Xi Chen , Xue Zhang

The rapid advancement of Artificial Intelligence has resulted in the advent of Large Language Models (LLMs) with the capacity to produce text that closely resembles human communication. These models have been seamlessly integrated into…

Machine Learning · Computer Science 2025-02-04 Zenon Lamprou , Yashar Moshfeghi

Large Language Models (LLMs) create exciting possibilities for powerful language processing tools to accelerate research in materials science. While LLMs have great potential to accelerate materials understanding and discovery, they…

Materials Science · Physics 2024-09-26 Santiago Miret , N M Anoop Krishnan

Metal additive manufacturing (AM) involves complex interdependencies among processes, materials, feedstock, and post-processing steps. However, the underlying relationships and domain knowledge remain fragmented across literature and static…

Information Retrieval · Computer Science 2025-07-29 Muhammad Tayyab Khan , Lequn Chen , Wenhe Feng , Seung Ki Moon

The startling success of ChatGPT and other large language models (LLMs) using transformer-based generative neural network architecture in applications such as natural language processing and image synthesis has many researchers excited…

Artificial Intelligence · Computer Science 2024-11-05 Venkat Venkatasubramanian , Arijit Chakraborty

Discovering materials with desirable properties in an efficient way remains a significant problem in materials science. Many studies have tackled this problem by using different sets of information available about the materials. Among them,…

Materials Science · Physics 2025-03-04 Onur Boyar , Indra Priyadarsini , Seiji Takeda , Lisa Hamada

Large language models (LLMs) integrated with autonomous agents hold significant potential for advancing scientific discovery through automated reasoning and task execution. However, applying LLM agents to drug discovery is still constrained…

Artificial Intelligence · Computer Science 2025-07-29 Kun Li , Zhennan Wu , Shoupeng Wang , Jia Wu , Shirui Pan , Wenbin Hu