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Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Multi-modality imaging improves disease diagnosis and reveals distinct deviations in tissues with anatomical properties. The existence of completely aligned and paired multi-modality neuroimaging data has proved its effectiveness in brain…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Guoyang Xie , Yawen Huang , Jinbao Wang , Jiayi Lyu , Feng Zheng , Yefeng Zheng , Yaochu Jin

Magnetic resonance imaging (MRI) is a widely used neuroimaging technique that can provide images of different contrasts (i.e., modalities). Fusing this multi-modal data has proven particularly effective for boosting model performance in…

Computer Vision and Pattern Recognition · Computer Science 2020-02-13 Tao Zhou , Huazhu Fu , Geng Chen , Jianbing Shen , Ling Shao

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

In this paper, we propose a bi-modality medical image synthesis approach based on sequential generative adversarial network (GAN) and semi-supervised learning. Our approach consists of two generative modules that synthesize images of the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Xin Yang , Yi Lin , Zhiwei Wang , Xin Li , Kwang-Ting Cheng

Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jihoon Cho , Xiaofeng Liu , Fangxu Xing , Jinsong Ouyang , Georges El Fakhri , Jinah Park , Jonghye Woo

Magnetic Resonance (MR) images of different modalities can provide complementary information for clinical diagnosis, but whole modalities are often costly to access. Most existing methods only focus on synthesizing missing images between…

Computer Vision and Pattern Recognition · Computer Science 2020-05-05 Bingyu Xin , Yifan Hu , Yefeng Zheng , Hongen Liao

Multi-modality images have been widely used and provide comprehensive information for medical image analysis. However, acquiring all modalities among all institutes is costly and often impossible in clinical settings. To leverage more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Qi Chang , Hui Qu , Zhennan Yan , Yunhe Gao , Lohendran Baskaran , Dimitris Metaxas

Generating multi-contrasts/modal MRI of the same anatomy enriches diagnostic information but is limited in practice due to excessive data acquisition time. In this paper, we propose a novel deep-learning model for joint reconstruction and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Wanyu Bian , Qingchao Zhang , Xiaojing Ye , Yunmei Chen

Cross-modality image synthesis is an active research topic with multiple medical clinically relevant applications. Recently, methods allowing training with paired but misaligned data have started to emerge. However, no robust and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Joel Honkamaa , Umair Khan , Sonja Koivukoski , Mira Valkonen , Leena Latonen , Pekka Ruusuvuori , Pekka Marttinen

Data scarcity and privacy concerns limit the availability of high-quality medical images for public use, which can be mitigated through medical image synthesis. However, current medical image synthesis methods often struggle to accurately…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Wenting Chen , Pengyu Wang , Hui Ren , Lichao Sun , Quanzheng Li , Yixuan Yuan , Xiang Li

Multi-modal medical image completion has been extensively applied to alleviate the missing modality issue in a wealth of multi-modal diagnostic tasks. However, for most existing synthesis methods, their inferences of missing modalities can…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Xiangxi Meng , Yuning Gu , Yongsheng Pan , Nizhuan Wang , Peng Xue , Mengkang Lu , Xuming He , Yiqiang Zhan , Dinggang Shen

Current multimodal medical image fusion typically assumes that source images are of high quality and perfectly aligned at the pixel level. Its effectiveness heavily relies on these conditions and often deteriorates when handling misaligned…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Dayong Su , Yafei Zhang , Huafeng Li , Jinxing Li , Yu Liu

Recent progress in multi-modal conditioned face synthesis has enabled the creation of visually striking and accurately aligned facial images. Yet, current methods still face issues with scalability, limited flexibility, and a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Jingjing Ren , Cheng Xu , Haoyu Chen , Xinran Qin , Lei Zhu

Multimodal medical image fusion (MMIF) aims to integrate images from different modalities to produce a comprehensive image that enhances medical diagnosis by accurately depicting organ structures, tissue textures, and metabolic information.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tao Luo , Weihua Xu

Image analysis using more than one modality (i.e. multi-modal) has been increasingly applied in the field of biomedical imaging. One of the challenges in performing the multimodal analysis is that there exist multiple schemes for fusing the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-19 Zhe Guo , Xiang Li , Heng Huang , Ning Guo , Quanzheng Li

Multi-modality magnetic resonance imaging (MRI) is essential for the diagnosis and treatment of brain tumors. However, missing modalities are commonly observed due to limitations in scan time, scan corruption, artifacts, motion, and…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Xiaojiao Xiao , Qinmin Vivian Hu , Guanghui Wang

We propose a deep mixture of multimodal hierarchical variational auto-encoders called MMHVAE that synthesizes missing images from observed images in different modalities. MMHVAE's design focuses on tackling four challenges: (i) creating a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Reuben Dorent , Nazim Haouchine , Alexandra Golby , Sarah Frisken , Tina Kapur , William Wells

Deep learning-based image fusion approaches have obtained wide attention in recent years, achieving promising performance in terms of visual perception. However, the fusion module in the current deep learning-based methods suffers from two…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Dongyu Rao , Xiao-Jun Wu , Tianyang Xu , Guoyang Chen
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