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Automatically generating one medical imaging modality from another is known as medical image translation, and has numerous interesting applications. This paper presents an interpretable generative modelling approach to medical image…

Image and Video Processing · Electrical Eng. & Systems 2020-05-08 Mikael Brudfors , John Ashburner , Parashkev Nachev , Yael Balbastre

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Georges El Fakhri , Jonghye Woo

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Current multi-modal image fusion methods typically rely on task-specific models, leading to high training costs and limited scalability. While generative methods provide a unified modeling perspective, they often suffer from slow inference…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Huayi Zhu , Xiu Shu , Youqiang Xiong , Qiao Liu , Rui Chen , Di Yuan , Xiaojun Chang , Zhenyu He

Multi-modality image fusion aims to combine different modalities to produce fused images that retain the complementary features of each modality, such as functional highlights and texture details. To leverage strong generative priors and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Zixiang Zhao , Haowen Bai , Yuanzhi Zhu , Jiangshe Zhang , Shuang Xu , Yulun Zhang , Kai Zhang , Deyu Meng , Radu Timofte , Luc Van Gool

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Existing multimodal conditional image synthesis (MCIS) methods generate images conditioned on any combinations of various modalities that require all of them must be exactly conformed, hindering the synthesis controllability and leaving the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Jianbin Zheng , Daqing Liu , Chaoyue Wang , Minghui Hu , Zuopeng Yang , Changxing Ding , Dacheng Tao

We introduce MHVAE, a deep hierarchical variational auto-encoder (VAE) that synthesizes missing images from various modalities. Extending multi-modal VAEs with a hierarchical latent structure, we introduce a probabilistic formulation for…

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

As an effective way to integrate the information contained in multiple medical images under different modalities, medical image synthesis and fusion have emerged in various clinical applications such as disease diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Yuhao Wang , Ruirui Liu , Zihao Li , Cailian Yang , Qiegen Liu

Dealing with missing modalities in Magnetic Resonance Imaging (MRI) and overcoming their negative repercussions is considered a hurdle in biomedical imaging. The combination of a specified set of modalities, which is selected depending on…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Reza Azad , Nika Khosravi , Mohammad Dehghanmanshadi , Julien Cohen-Adad , Dorit Merhof

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

We propose a method called integrated diffusion for combining multimodal datasets, or data gathered via several different measurements on the same system, to create a joint data diffusion operator. As real world data suffers from both local…

Machine Learning · Computer Science 2022-03-07 Manik Kuchroo , Abhinav Godavarthi , Alexander Tong , Guy Wolf , Smita Krishnaswamy

Multi-modal fusion approaches aim to integrate information from different data sources. Unlike natural datasets, such as in audio-visual applications, where samples consist of "paired" modalities, data in healthcare is often collected…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Multimodal MR image synthesis aims to generate missing modality images by effectively fusing and mapping from a subset of available MRI modalities. Most existing methods adopt an image-to-image translation paradigm, treating multiple…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Tao Song , Yicheng Wu , Minhao Hu , Xiangde Luo , Linda Wei , Guotai Wang , Yi Guo , Feng Xu , Shaoting Zhang

Medical image synthesis remains challenging due to misalignment noise during training. Existing methods have attempted to address this challenge by incorporating a registration-guided module. However, these methods tend to overlook the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuanpu Li , Zeli Chen , Yiwen Zhang , Liming Zhong , Wei Yang