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In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider the construction of foundational models from three perspectives, namely, dataset construction, model design, and thorough…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

In the field of medical imaging, AI-assisted techniques such as object detection, segmentation, and classification are widely employed to alleviate the workload of physicians and doctors. However, single-task models are predominantly used,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Fan Li , Arun Iyengar , Lanyu Xu

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can…

Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Oral and maxillofacial radiology plays a vital role in dental healthcare, but radiographic image interpretation is limited by a shortage of trained professionals. While AI approaches have shown promise, existing dental AI systems are…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Xinrui Huang , Fan Xiao , Dongming He , Anqi Gao , Dandan Li , Xiaofan Zhang , Shaoting Zhang , Xudong Wang

3D medical image analysis is essential for modern healthcare, yet traditional task-specific models are inadequate due to limited generalizability across diverse clinical scenarios. Multimodal large language models (MLLMs) offer a promising…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Yiming Shi , Xun Zhu , Kaiwen Wang , Ying Hu , Chenyi Guo , Miao Li , Ji Wu

Chest X-ray imaging is a critical diagnostic tool for identifying pulmonary diseases. However, manual interpretation of these images is time-consuming and error-prone. Automated systems utilizing convolutional neural networks (CNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2025-11-25 Saurabh Agarwal , K. V. Arya , Yogesh Kumar Meena

As embodied AI systems become increasingly multi-modal, personalized, and interactive, they must learn effectively from diverse sensory inputs, adapt continually to user preferences, and operate safely under resource and privacy…

Current medical AI systems are often limited to narrow applications, hindering widespread adoption. We present MedVersa, a generalist foundation model trained on tens of millions of compiled medical instances. MedVersa unlocks generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Hong-Yu Zhou , Julián Nicolás Acosta , Subathra Adithan , Suvrankar Datta , Eric J. Topol , Pranav Rajpurkar

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang

Contemporary cardiovascular management involves complex consideration and integration of multimodal cardiac datasets, where each modality provides distinct but complementary physiological characteristics. While the effective integration of…

Target volume contouring for radiation therapy is considered significantly more challenging than the normal organ segmentation tasks as it necessitates the utilization of both image and text-based clinical information. Inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Yeona Cho , Ik Jae Lee , Jin Sung Kim , Jong Chul Ye

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

3D medical image analysis is of great importance in disease diagnosis and treatment. Recently, multimodal large language models (MLLMs) have exhibited robust perceptual capacity, strong cross-modal alignment, and promising generalizability.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yang Yu , Dunyuan Xu , Yaoqian Li , Xiaomeng Li , Jinpeng Li , Pheng-Ann Heng

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

Traditional biomedical artificial intelligence (AI) models, designed for specific tasks or modalities, often exhibit limited flexibility in real-world deployment and struggle to utilize holistic information. Generalist AI holds the…

Social problems stemming from the shortage of radiologists are intensifying, and artificial intelligence is being highlighted as a potential solution. Recently emerging large-scale generative AI has expanded from large language models…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Inwoo Seo , Eunkyoung Bae , Joo-Young Jeon , Young-Sang Yoon , Jiho Cha
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