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Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Generative models have revolutionized Artificial Intelligence (AI), particularly in multimodal applications. However, adapting these models to the medical domain poses unique challenges due to the complexity of medical data and the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Daniele Molino , Francesco di Feola , Linlin Shen , Paolo Soda , Valerio Guarrasi

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

X-ray medical report generation is one of the important applications of artificial intelligence in healthcare. With the support of large foundation models, the quality of medical report generation has significantly improved. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Futian Wang , Yuhan Qiao , Xiao Wang , Fuling Wang , Yuxiang Zhang , Dengdi Sun

X-ray imaging is a ubiquitous in radiology, yet most existing AI foundation models are limited to chest anatomy and fail to generalize across broader clinical tasks. In this work, we introduce XR-0, the multi-anatomy X-ray foundation model…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Nishank Singla , Krisztian Koos , Farzin Haddadpour , Amin Honarmandi Shandiz , Lovish Chum , Xiaojian Xu , Qing Jin , Erhan Bas

Developing generalist foundation model has recently attracted tremendous attention among researchers in the field of AI for Medicine (AI4Medicine). A pivotal insight in developing these models is their reliance on dataset scaling, which…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Xiaoman Zhang , Chaoyi Wu , Ziheng Zhao , Jiayu Lei , Ya Zhang , Yanfeng Wang , Weidi Xie

Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are primarily limited to a small set of modalities and tasks, which hinders the development of large-scale…

Machine Learning · Computer Science 2025-03-21 Wei Dai , Peilin Chen , Malinda Lu , Daniel Li , Haowen Wei , Hejie Cui , Paul Pu Liang

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Artificial intelligence (AI) is vital in ophthalmology, tackling tasks like diagnosis, classification, and visual question answering (VQA). However, existing AI models in this domain often require extensive annotation and are task-specific,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Danli Shi , Weiyi Zhang , Xiaolan Chen , Yexin Liu , Jiancheng Yang , Siyu Huang , Yih Chung Tham , Yingfeng Zheng , Mingguang He

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

Machine Learning · Computer Science 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Medical image analysis is crucial in modern radiological diagnostics, especially given the exponential growth in medical imaging data. The demand for automated report generation systems has become increasingly urgent. While prior research…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hao Chen , Wei Zhao , Yingli Li , Tianyang Zhong , Yisong Wang , Youlan Shang , Lei Guo , Junwei Han , Tianming Liu , Jun Liu , Tuo Zhang

Developing a generalist radiology diagnosis system can greatly enhance clinical diagnostics. In this paper, we introduce RadDiag, a foundational model supporting 2D and 3D inputs across various modalities and anatomies, using a…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Qiaoyu Zheng , Weike Zhao , Chaoyi Wu , Xiaoman Zhang , Lisong Dai , Hengyu Guan , Yuehua Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Many clinical tasks require an understanding of specialized data, such as medical images and genomics, which is not typically found in general-purpose large multimodal models. Building upon Gemini's multimodal models, we develop several…

Medicine is inherently multimodal and multitask, with diverse data modalities spanning text, imaging. However, most models in medical field are unimodal single tasks and lack good generalizability and explainability. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Lijian Xu , Hao Sun , Ziyu Ni , Hongsheng Li , Shaoting Zhang

Breast cancer is one of the leading causes of death among women worldwide. We introduce Mammo-FM, the first foundation model specifically for mammography, pretrained on the largest and most diverse dataset to date - 140,677 patients…

The ability to detect manipulated visual content is becoming increasingly important in many application fields, given the rapid advances in image synthesis methods. Of particular concern is the possibility of modifying the content of…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Giada Zingarini , Davide Cozzolino , Riccardo Corvi , Giovanni Poggi , Luisa Verdoliva

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Large Vision-Language Models (LVLMs) are capable of handling diverse data types such as imaging, text, and physiological signals, and can be applied in various fields. In the medical field, LVLMs have a high potential to offer substantial…

Multi-modal large language models (MLLMs) have shown impressive capabilities as a general-purpose interface for various visual and linguistic tasks. However, building a unified MLLM for multi-task learning in the medical field remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Xun Zhu , Ying Hu , Fanbin Mo , Miao Li , Ji Wu