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We analyze a class of network motifs in which a short, two-node positive feed- back motif is inserted in a three-node negative feedback loop. We demonstrate that such networks can undergo a bifurcation to a state where a stable fixed point…
Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes. In this paper we analyse…
We experimentally and theoretically investigate the dynamics of inhibitory coupled self-driven oscillators on a star network in which a single central hub node is connected to $k$ peripheral arm nodes. The system consists of water-in-oil…
Microresonators are micron-scale optical systems that confine light using total internal reflection. These optical systems have gained interest in the last two decades due to their compact sizes, unprecedented measurement capabilities, and…
Mutation is introduced into autocatalytic reaction networks. Examples of low dimensional dynamical systems --- n = 2, 3 and 4 --- are discussed and complete qualitative analysis is presented. Error thresholds known from simple…
Computer algebra methods for analyzing reaction networks often rely on the assumption of mass-action kinetics, which transform the governing ODEs into polynomial systems amenable to techniques such as Gr\"obner basis computation and related…
Hopf bifurcation in networks of coupled ODEs creates periodic states in which the relative phases of nodes are well defined near bifurcation. When the network is a fully inhomogeneous nearest-neighbour coupled unidirectional ring, and node…
Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing the network topologies that can…
Pulse-coupled systems such as spiking neural networks exhibit nontrivial invariant sets in the form of attracting yet unstable saddle periodic orbits where units are synchronized into groups. Heteroclinic connections between such orbits may…
In networks of nonlinear oscillators, symmetries place hard constraints on the system that can be exploited to predict universal dynamical features and steady-states, providing a rare generic organizing principle for far-from-equilibrium…
According to the chemical reaction network theory, the topology of a certain class of chemical reaction networks, regardless of the kinetic details, sets a limit on the dynamical properties that a particular network can potentially admit;…
We consider stochastic reaction networks modeled by continuous-time Markov chains. Such reaction networks often contain many reactions, potentially occurring at different time scales, and have unknown parameters (kinetic rates, total…
This work addresses whether a reaction network, taken with mass-action kinetics, is multistationary, that is, admits more than one positive steady state in some stoichiometric compatibility class. We build on previous work on the effect…
The model of a memristor-based oscillator with cubic nonlinearity is studied. The considered system has infinitely many equilibrium points, which build a line of equilibria in the phase space. Numerical modeling of the dynamics is combined…
Many reaction networks arising in applications are multistationary, that is, they have the capacity for more than one steady state; while some networks exhibit absolute concentration robustness (ACR), which means that some species…
This work continues the analysis of complex dynamics in a class of bidimensional nonlinear hybrid dynamical systems with resets modeling neuronal voltage dynamics with adaptation and spike emission. We show that these models can generically…
Triadic interactions are special types of higher-order interactions that occur when regulator nodes modulate the interactions between other two or more nodes. In presence of triadic interactions, a percolation process occurring on a…
We consider local bifurcations of equilibria in dynamical systems arising from chemical reaction networks with mass action kinetics. In particular, given any mass action network admitting a local bifurcation of equilibria, assuming only a…
Synchronization is an essential collective phenomenon in networks of interacting oscillators. Twisted states are rotating wave solutions in ring networks where the oscillator phases wrap around the circle in a linear fashion. Here, we…
In the brain, coherent neuronal activities often appear simultaneously in multiple frequency bands, e.g., as combinations of alpha (8-12 Hz), beta (12.5-30 Hz), gamma (30-120 Hz) oscillations, among others. These rhythms are believed to…