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Emerging infectious diseases and climate change are two of the major challenges in 21st century. Although over the past decades, highly-resolved mathematical models have contributed in understanding dynamics of infectious diseases and are…

Populations and Evolution · Quantitative Biology 2025-10-13 Julia Bicker , René Schmieding , Michael Meyer-Hermann , Martin J. Kühn

Over a year after the start of the COVID-19 epidemics, we are still facing the virus and it is hard to correctly predict its future spread over weeks to come, as well as the impacts of potential political interventions. Current epidemic…

Multiagent Systems · Computer Science 2021-12-03 Benoit Doussin , Carole Adam , Didier Georges

Coupled human-environment systems are increasingly being understood as complex adaptive systems (CAS), in which micro-level interactions between components lead to emergent behavior. Agent-based models (ABMs) hold great promise for…

Applications · Statistics 2026-02-20 Dylan Munson , Arijit Dey , Simon Mak

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

The onset of the COVID-19 pandemic drove a widespread, often uncoordinated effort by research groups to develop mathematical models of SARS-CoV-2 to study its spread and inform control efforts. The urgent demand for insight at the outset of…

Populations and Evolution · Quantitative Biology 2023-06-21 Alexander N. Pillai , Kok Ben Toh , Dianela Perdomo , Sanjana Bhargava , Arlin Stoltzfus , Ira M. Longini , Carl A. B. Pearson , Thomas J. Hladish

The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…

Agent based models (ABMs) are a useful tool for modeling spatio-temporal population dynamics, where many details can be included in the model description. Their computational cost though is very high and for stochastic ABMs a lot of…

Dynamical Systems · Mathematics 2022-05-11 Stefanie Winkelmann , Johannes Zonker , Christof Schütte , Natasa Djurdjevac Conrad

Agent-based simulators (ABS) are a popular epidemiological modelling tool to study the impact of various non-pharmaceutical interventions in managing an epidemic in a city (or a region). They provide the flexibility to accurately model a…

Physics and Society · Physics 2025-10-13 Daksh Mittal , Sandeep Juneja

Agent-based epidemic models (ABMs) encode behavioral and policy heterogeneity but are too slow for nightly hospital planning. We develop county-ready surrogates that learn directly from exascale ABM trajectories using Universal Differential…

This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

Over the years, population-level tobacco control policies have considerably reduced smoking prevalence worldwide. However, the rate of decline of smoking prevalence is slowing down. Therefore, there is a need for models that capture the…

Physics and Society · Physics 2022-07-19 Adarsh Prabhakaran , Valerio Restocchi , Benjamin D. Goddard

This paper presents a hybrid modeling approach that couples an Agent-Based Model (ABM) with a partial differential equation (PDE) model in an epidemic setting to simulate the spatial spread of infectious diseases using a compartmental…

Multiagent Systems · Computer Science 2026-01-21 Kristina Kehrer , Tim O. F. Conrad

Agent-based models (ABMs) simulate complex systems by capturing the bottom-up interactions of individual agents comprising the system. Many complex systems of interest, such as epidemics or financial markets, involve thousands or even…

Agent-based models (ABMs) provide an intuitive and powerful framework for studying social dynamics by modeling the interactions of individuals from the perspective of each individual. In addition to simulating and forecasting the dynamics…

Dynamical Systems · Mathematics 2024-02-22 Jan-Hendrik Niemann , Stefan Klus , Nataša Djurdjevac Conrad , Christof Schütte

Agent-based models (ABMs) provide a powerful framework to describe complex systems composed of interacting entities, capable of producing emergent collective behaviours such as consensus formation or clustering. However, the increasing…

Optimization and Control · Mathematics 2025-07-29 Angela Monti , Fasma Diele , Dante Kalise

Running agent-based models (ABMs) is a burdensome computational task, specially so when considering the flexibility ABMs intrinsically provide. This paper uses a bundle of model configuration parameters along with obtained results from a…

Multiagent Systems · Computer Science 2020-01-14 Bernardo Alves Furtado

Today's most troublesome population health challenges are often driven by social and environmental determinants, which are difficult to model using traditional epidemiological methods. We agree with those who have argued for the wider…

Multiagent Systems · Computer Science 2020-02-07 Eric Silverman , Umberto Gostoli , Stefano Picascia , Jonatan Almagor , Mark McCann , Richard Shaw , Claudio Angione

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

Machine Learning · Computer Science 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Agent-based modelling (ABMing) is a powerful and intuitive approach to modelling complex systems; however, the intractability of ABMs' likelihood functions and the non-differentiability of the mathematical operations comprising these models…

Multiagent Systems · Computer Science 2023-05-25 Arnau Quera-Bofarull , Ayush Chopra , Anisoara Calinescu , Michael Wooldridge , Joel Dyer
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