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Understanding how genetically encoded rules drive and guide complex neuronal growth processes is essential to comprehending the brain's architecture, and agent-based models (ABMs) offer a powerful simulation approach to further develop this…

Computational Engineering, Finance, and Science · Computer Science 2024-05-24 Tobias Duswald , Lukas Breitwieser , Thomas Thorne , Barbara Wohlmuth , Roman Bauer

The need to forecast COVID-19 related variables continues to be pressing as the epidemic unfolds. Different efforts have been made, with compartmental models in epidemiology and statistical models such as AutoRegressive Integrated Moving…

Applications · Statistics 2020-10-07 Bahman Rostami-Tabar , Juan F. Rendon-Sanchez

Global problems, such as pandemics and climate change, require rapid international coordination and diffusion of policy. These phenomena are rare however, with one notable example being the international policy response to the COVID-19…

Multiagent Systems · Computer Science 2023-02-23 Yannick Oswald , Nick Malleson , Keiran Suchak

Real-world multi-agent systems are often dynamic and continuous, where the agents co-evolve and undergo changes in their trajectories and interactions over time. For example, the COVID-19 transmission in the U.S. can be viewed as a…

Machine Learning · Computer Science 2024-03-04 Zijie Huang , Jeehyun Hwang , Junkai Zhang , Jinwoo Baik , Weitong Zhang , Dominik Wodarz , Yizhou Sun , Quanquan Gu , Wei Wang

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

Forecasting the short-term spread of an ongoing disease outbreak is a formidable challenge due to the complexity of contributing factors, some of which can be characterized through interlinked, multi-modality variables such as…

Machine Learning · Computer Science 2024-04-11 Hongru Du , Jianan Zhao , Yang Zhao , Shaochong Xu , Xihong Lin , Yiran Chen , Lauren M. Gardner , Hao Frank Yang

Ordinary differential equations (ODEs) are widely used to model biological, (bio-)chemical and technical processes. The parameters of these ODEs are often estimated from experimental data using ODE-constrained optimisation. This article…

Optimization and Control · Mathematics 2015-11-06 Anna Fiedler , Fabian J. Theis , Jan Hasenauer

Non-pharmaceutical interventions (NPIs) are commonly used tools for controlling infectious disease transmission when pharmaceutical options are unavailable. Yet, identifying effective interventions that minimize societal disruption remains…

Multiagent Systems · Computer Science 2026-04-03 Anja Wolpers , Johannes Ponge , Adelinde M. Uhrmacher

This study investigated the performance, explainability, and robustness of deployed artificial intelligence (AI) models in predicting mortality during the COVID-19 pandemic and beyond. The first study of its kind, we found that Bayesian…

Machine Learning · Computer Science 2023-11-30 Jacob R. Epifano , Stephen Glass , Ravi P. Ramachandran , Sharad Patel , Aaron J. Masino , Ghulam Rasool

We present a memory-bounded optimization approach for solving infinite-horizon decentralized POMDPs. Policies for each agent are represented by stochastic finite state controllers. We formulate the problem of optimizing these policies as a…

Artificial Intelligence · Computer Science 2012-06-26 Christopher Amato , Daniel S Bernstein , Shlomo Zilberstein

In the wake of COVID-19, every government huddles to find the best interventions that will reduce the number of infection cases while minimizing the economic impact. However, with many intervention policies available, how should one decide…

Optimization and Control · Mathematics 2021-04-19 Chang Liu , Akshay Budhkar

Modelling how shocks propagate in supply chains is an increasingly important challenge in economics. Its relevance has been highlighted in recent years by events such as Covid-19 and the Russian invasion of Ukraine. Agent-based models…

Physics and Society · Physics 2025-11-10 Saad Hamid , José Moran , Luca Mungo , Arnau Quera-Bofarull , Sebastian Towers

This article proposes a methodology to model and simulate complex systems, based on IRM4MLS, a generic agent-based meta-model able to deal with multi-level systems. This methodology permits the engineering of dynamic multi-level agent-based…

Multiagent Systems · Computer Science 2013-11-21 Jean-Baptiste Soyez , Gildas Morvan , Daniel Dupont , Rochdi Merzouki

We introduce DeepABM, a framework for agent-based modeling that leverages geometric message passing of graph neural networks for simulating action and interactions over large agent populations. Using DeepABM allows scaling simulations to…

Simulating the spread of infectious diseases in human communities is critical for predicting the trajectory of an epidemic and verifying various policies to control the devastating impacts of the outbreak. Many existing simulators are based…

Populations and Evolution · Quantitative Biology 2021-04-22 Arash Mehrjou , Ashkan Soleymani , Amin Abyaneh , Samir Bhatt , Bernhard Schölkopf , Stefan Bauer

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

Agent-based models (ABMs) are fit to model heterogeneous, interacting systems like financial markets. We present the latest advances in Evology: a heterogeneous, empirically calibrated market ecology agent-based model of the US stock…

Multiagent Systems · Computer Science 2023-02-03 Aymeric Vie , J. Doyne Farmer

Optimal control of interdependent epidemics spreading over complex networks is a critical issue. We first establish a framework to capture the coupling between two epidemics, and then analyze the system's equilibrium states by categorizing…

Systems and Control · Computer Science 2017-10-19 Juntao Chen , Rui Zhang , Quanyan Zhu

Amid the ongoing COVID-19 pandemic, public health authorities and the general population are striving to achieve a balance between safety and normalcy. Ever changing conditions call for the development of theory and simulation tools to…

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