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The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

We introduce a new model of the human corneal stroma, regarded as a fluid-saturated continuum, able to describe surface flattening and thickness thinning observed in several pathological conditions. In contrast with more common approaches…

Tissues and Organs · Quantitative Biology 2026-01-05 A. Giammarini , A. Pandolfi

Diffusion-driven processes are important phenomena of materials science in the field of energy conversion and transmission. During the conversion from chemical energy to electrical energy, the species diffusion is generally linked to the…

Applied Physics · Physics 2021-02-23 Jay Santoki

A model to describe the arising of new structures in an initial homogeneous biological system is proposed. The essay is motivated by the intention to work on a non-equilibrium situation grouping together several mechanisms and processes as:…

Biological Physics · Physics 2007-05-23 P. C. T. Dajello , P. R. Hauser

Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelial cells adhere to each other and maintain the tissue layer…

Biological Physics · Physics 2024-10-04 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Using an interface displacement model derived from a microscopic density functional theory we investigate thin liquidlike wetting layers adsorbed on flat substrates with an embedded chemical heterogeneity forming a stripe. For a wide range…

Soft Condensed Matter · Physics 2009-10-31 C. Bauer , S. Dietrich , A. O. Parry

A phase-field approach describing the dynamics of a strained solid in contact with its melt is developed. By rigorous asymptotic analysis we show that the sharp-interface limit of this model recovers the continuum model equations for the…

Statistical Mechanics · Physics 2007-05-23 Klaus Kassner , Chaouqi Misbah , Judith Mueller , Jens Kappey , Peter Kohlert

The phase transitions in the transverse field Ising model in a competing spatially modulated (periodic and oscillatory) longitudinal field are studied numerically. There is a multiphase point in absence of the transverse field where the…

Statistical Mechanics · Physics 2016-08-31 Parongama Sen

The Cahn--Hilliard equations are a versatile model for describing the evolution of complex morphologies. In this paper we present a computational pipeline for the numerical solution of a ternary phase-field model for describing the…

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

We study elasticity-driven morphological transitions of soft spherical core shell structures in which the core can be treated as an isotropic elastic continuum and the surface or shell as a tensionless liquid layer, whose elastic response…

Soft Condensed Matter · Physics 2013-11-13 Craig Fogle , Amy C. Rowat , Alex J. Levine , Joseph Rudnick

We analytically derive an equation describing vesicle evolution in a fluid where some stationary flow is excited regarding that the vesicle shape is close to a sphere. A character of the evolution is governed by two dimensionless…

Soft Condensed Matter · Physics 2009-11-13 V. V. Lebedev , K. S. Turitsyn , S. S. Vergeles

Recent years have seen a significant interest in using phase field approaches to model hydraulic fracture, so as to optimise a process that is key to industries such as petroleum engineering, mining and geothermal energy extraction. Here,…

Computational Engineering, Finance, and Science · Computer Science 2025-06-24 Y. Navidtehrani , C. Betegón , J. Vallejos , E. Martínez-Pañeda

Cellular membranes are a heterogeneous mix of lipids, proteins and small molecules. Special groupings of saturated lipids and cholesterol form a liquid-ordered phase, known as `lipid rafts,' serving as platforms for signaling, trafficking…

Quantitative Methods · Quantitative Biology 2015-05-13 Tristan S. Ursell , William S. Klug , Rob Phillips

Inspired by epithelial morphogenesis, we consider a minimal model for the shaping of a surface driven by $p$-atic topological defects. We show that a positive (negative) defect can dynamically generate a (hyperbolic) cone whose shape…

Soft Condensed Matter · Physics 2023-03-02 Farzan Vafa , L. Mahadevan

We investigate a class of cyclic evolutions for %the cyclic evolution of driven two-level quantum systems (effective spin-1/2) with a particular focus on the geometric characteristics of the driving and their specific imprints on the…

Mesoscale and Nanoscale Physics · Physics 2020-05-20 Zu-Jian Ying , Paola Gentile , José Pablo Baltanàs , Diego Frustaglia , Carmine Ortix , Mario Cuoco

The search for the QCD critical point in heavy-ion collision experiments requires dynamical simulations of the bulk evolution of QCD matter as well as of fluctuations. We consider two essential ingredients of such a simulation: a generic…

Nuclear Theory · Physics 2018-08-15 M. Stephanov , Y. Yin

The process of programmed cell death, namely apoptosis, is a natural mechanism that regulates healthy tissue, multicellular structures, and homeostasis. An improved understanding of apoptosis can significantly enhance our knowledge of…

Cell Behavior · Quantitative Biology 2026-03-12 Daniel A. Vaughan , Anna M. Piccinini , Mischa Zelzer , Etienne Farcot , Bindi S. Brook , Kris Van-der-Zee , Luis Espath

The Cahn-Hilliard equation is a fundamental model that describes the phase separation process in multi-component mixtures. It has been successfully extended to many different contexts in several scientific fields. In this survey article, we…

Analysis of PDEs · Mathematics 2022-06-22 Hao Wu

Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization…

Cell Behavior · Quantitative Biology 2014-02-21 Olivier Cochet-Escartin , Jonas Ranft , Pascal Silberzan , Philippe Marcq
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