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Overconfidence in deep learning models poses a significant risk in high-stakes medical imaging tasks, particularly in multi-label classification of chest X-rays, where multiple co-occurring pathologies must be detected simultaneously. This…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Yehudit Aperstein , Amit Tzahar , Alon Gottlib , Tal Verber , Ravit Shagan Damti , Alexander Apartsin

Radiologists face high burnout rates, partially due to the increasing volume of Chest X-rays (CXRs) requiring interpretation and reporting. Automated CXR report generation holds promise for reducing this burden and improving patient care.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Aaron Nicolson , Jason Dowling , Bevan Koopman

Agentic AI is advancing rapidly, yet truly autonomous medical-imaging triage, where a system decides when to stop, escalate, or defer under real constraints, remains relatively underexplored. To address this gap, we introduce AT-CXR, an…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Xueyang Li , Mingze Jiang , Gelei Xu , Jun Xia , Mengzhao Jia , Danny Chen , Yiyu Shi

AI agents with tool-use capabilities show promise for integrating the domain expertise of various tools. In the medical field, however, tools are usually AI models that are inherently error-prone and can produce contradictory responses.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Zheang Huai , Honglong Yang , Xiaomeng Li

We predict mechanical ventilation requirement and mortality using computational modeling of chest radiographs (CXRs) for coronavirus disease 2019 (COVID-19) patients. This two-center, retrospective study analyzed 530 deidentified CXRs from…

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Most CRC deaths are the result of progression of metastases. The assessment of metastases is done using the RECIST…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Xin J. Hunt , Ralph Abbey , Ricky Tharrington , Joost Huiskens , Nina Wesdorp

Chest X ray (CXR) imaging remains a critical diagnostic tool for thoracic conditions, but current automated systems face limitations in pathology coverage, diagnostic accuracy, and integration of visual and textual reasoning. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Wenting Chen , Yi Dong , Zhaojun Ding , Yucheng Shi , Yifan Zhou , Fang Zeng , Yijun Luo , Tianyu Lin , Yihang Su , Yichen Wu , Kai Zhang , Zhen Xiang , Tianming Liu , Ninghao Liu , Lichao Sun , Yixuan Yuan , Xiang Li

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

An important goal in the field of human-AI interaction is to help users more appropriately trust AI systems' decisions. A situation in which the user may particularly benefit from more appropriate trust is when the AI receives anomalous…

Human-Computer Interaction · Computer Science 2022-04-29 Marissa Radensky , Dustin Burson , Rajya Bhaiya , Daniel S. Weld

Chest radiography has been a recommended procedure for patient triaging and resource management in intensive care units (ICUs) throughout the COVID-19 pandemic. The machine learning efforts to augment this workflow have been long challenged…

Radiologists can classify a mammogram as normal or abnormal at better than chance levels after less than a second's exposure to the images. In this work, we combine these radiologists' gist inputs into pre-trained machine learning models to…

Medical Physics · Physics 2019-12-12 Skylar W. Wurster , Arkadiusz Sitek , Jian Chen , Karla Evans , Gaeun Kim , Jeremy M. Wolfe

In this paper, we present the major results from the Covid Radiographic imaging System based on AI (Co.R.S.A.) project, which took place in Italy. This project aims to develop a state-of-the-art AI-based system for diagnosing Covid-19…

Image and Video Processing · Electrical Eng. & Systems 2024-05-21 Carlo Alberto Barbano , Riccardo Renzulli , Marco Grosso , Domenico Basile , Marco Busso , Marco Grangetto

The COVID-19 pandemic has strained global public health, necessitating accurate diagnosis and intervention to control disease spread and reduce mortality rates. This paper introduces an interpretable deep survival prediction model designed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Zhusi Zhong , Jie Li , Zhuoqi Ma , Scott Collins , Harrison Bai , Paul Zhang , Terrance Healey , Xinbo Gao , Michael K. Atalay , Zhicheng Jiao

Current approaches to explaining the decisions of deep learning systems for medical tasks have focused on visualising the elements that have contributed to each decision. We argue that such approaches are not enough to "open the black box"…

Artificial Intelligence · Computer Science 2018-06-04 William Gale , Luke Oakden-Rayner , Gustavo Carneiro , Andrew P Bradley , Lyle J Palmer

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Understanding the internal physiological changes accompanying the aging process is an important aspect of medical image interpretation, with the expected changes acting as a baseline when reporting abnormal findings. Deep learning has…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Matthew MacPherson , Keerthini Muthuswamy , Ashik Amlani , Charles Hutchinson , Vicky Goh , Giovanni Montana

Chest X-ray (CXR) images are commonly compressed to a lower resolution and bit depth to reduce their size, potentially altering subtle diagnostic features. Radiologists use windowing operations to enhance image contrast, but the impact of…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Alessandro Wollek , Sardi Hyska , Bastian Sabel , Michael Ingrisch , Tobias Lasser

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

Machine Learning · Computer Science 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

This study presents a novel multi-model fusion framework leveraging two state-of-the-art large language models (LLMs), ChatGPT and Claude, to enhance the reliability of chest X-ray interpretation on the CheXpert dataset. From the full…

Computation and Language · Computer Science 2025-10-21 Md Kamrul Siam , Md Jobair Hossain Faruk , Jerry Q. Cheng , Huanying Gu

Longitudinal chest X-ray (CXR) interpretation requires reasoning over disease evolution across multiple patient visits, yet most existing medical VQA benchmarks focus on single images or short-horizon image pairs. We introduce MI-CXR, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Sunghwan Steve Cho , Yunseok Han , Jaeyoung Do
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