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The chest X-ray (CXR) is by far the most commonly performed radiological examination for screening and diagnosis of many cardiac and pulmonary diseases. There is an immense world-wide shortage of physicians capable of providing rapid and…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Jonathan Laserson , Christine Dan Lantsman , Michal Cohen-Sfady , Itamar Tamir , Eli Goz , Chen Brestel , Shir Bar , Maya Atar , Eldad Elnekave

COVID-19, due to its accelerated spread has brought in the need to use assistive tools for faster diagnosis in addition to typical lab swab testing. Chest X-Rays for COVID cases tend to show changes in the lungs such as ground glass…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Gayathiri Murugamoorthy , Naimul Khan

In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Artificial Intelligence (AI) has made leapfrogs in development across all the industrial sectors especially when deep learning has been introduced. Deep learning helps to learn the behaviour of an entity through methods of recognising and…

Machine Learning · Computer Science 2021-04-30 Qinghao Ye , Jun Xia , Guang Yang

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Zhijin He , Alan B. McMillan

Clinical deployment of chest radiograph classifiers requires models that can be updated as new datasets become available without retraining on previously observed data or degrading validated performance. We study a task-incremental…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muthu Subash Kavitha , Anas Zafar , Amgad Muneer , Jia Wu

Deep learning models achieve strong performance in chest radiograph (CXR) interpretation, yet fairness and reliability concerns persist. Models often show uneven accuracy across patient subgroups, leading to hidden failures not reflected in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Han-Jay Shu , Wei-Ning Chiu , Shun-Ting Chang , Meng-Ping Huang , Takeshi Tohyama , Ahram Han , Po-Chih Kuo

In the field of eXplainable AI (XAI), robust "blackbox" algorithms such as Convolutional Neural Networks (CNNs) are known for making high prediction performance. However, the ability to explain and interpret these algorithms still require…

Machine Learning · Computer Science 2021-11-25 Shaw-Hwa Lo , Yiqiao Yin

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Recently large vision-language models have shown potential when interpreting complex images and generating natural language descriptions using advanced reasoning. Medicine's inherently multimodal nature incorporating scans and text-based…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Naman Sharma

Recent epidemiological data report that worldwide more than 53 million people have been infected by SARS-CoV-2, resulting in 1.3 million deaths. The disease has been spreading very rapidly and few months after the identification of the…

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…

Artificial Intelligence · Computer Science 2024-04-18 Nantika Nguycharoen

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

The field of Explainable Artificial Intelligence (XAI) aims to build explainable and interpretable machine learning (or deep learning) methods without sacrificing prediction performance. Convolutional Neural Networks (CNNs) have been…

Computer Vision and Pattern Recognition · Computer Science 2021-11-23 Shaw-Hwa Lo , Yiqiao Yin

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

Artificial intelligence (AI) is increasingly permeating healthcare, from physician assistants to consumer applications. Since AI algorithm's opacity challenges human interaction, explainable AI (XAI) addresses this by providing AI…

Detecting and classifying lesions in breast ultrasound images is a promising application of artificial intelligence (AI) for reducing the burden of cancer in regions with limited access to mammography. Such AI systems are more likely to be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Arianna Bunnell , Yannik Glaser , Dustin Valdez , Thomas Wolfgruber , Aleen Altamirano , Carol Zamora González , Brenda Y. Hernandez , Peter Sadowski , John A. Shepherd

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu