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Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Jian Wang , Xin Yang , Xiaohong Jia , Wufeng Xue , Rusi Chen , Yanlin Chen , Xiliang Zhu , Lian Liu , Yan Cao , Jianqiao Zhou , Dong Ni , Ning Gu

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu

Objectives: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. Methods: Prior study presented an algorithm which is able to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Jingxi Weng , Benjamin Wildman-Tobriner , Mateusz Buda , Jichen Yang , Lisa M. Ho , Brian C. Allen , Wendy L. Ehieli , Chad M. Miller , Jikai Zhang , Maciej A. Mazurowski

Over the past decades, the incidence of thyroid cancer has been increasing globally. Accurate and early diagnosis allows timely treatment and helps to avoid over-diagnosis. Clinically, a nodule is commonly evaluated from both transverse and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Han Huang , Yijie Dong , Xiaohong Jia , Jianqiao Zhou , Dong Ni , Jun Cheng , Ruobing Huang

The incidence of thyroid nodule is very high and generally increases with the age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid nodule can be completely cured if detected early. Fine needle aspiration cytology is…

Computer Vision and Pattern Recognition · Computer Science 2012-11-06 Jie Zhao , Wei Zheng , Li Zhang , Hua Tian

Ultrasound examination is widely used in the clinical diagnosis of thyroid nodules (benign/malignant). However, the accuracy relies heavily on radiologist experience. Although deep learning techniques have been investigated for thyroid…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yuchen Wang , Zhongyu Li , Xiangxiang Cui , Liangliang Zhang , Xiang Luo , Meng Yang , Shi Chang

Weakly supervised segmentation methods can delineate thyroid nodules in ultrasound images efficiently using training data with coarse labels, but suffer from: 1) low-confidence pseudo-labels that follow topological priors, introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jianning Chi , Zelan Li , Geng Lin , MingYang Sun , Xiaosheng Yu

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer…

Computation and Language · Computer Science 2024-03-20 Cheng Peng , Zehao Yu , Kaleb E Smith , Wei-Hsuan Lo-Ciganic , Jiang Bian , Yonghui Wu

The diagnosis of thyroid nodule cancers commonly utilizes ultrasound images. Several studies showed that deep learning algorithms designed to classify benign and malignant thyroid nodules could match radiologists' performance. However, data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Jichen Yang , Jikai Zhang , Benjamin Wildman-Tobriner , Maciej A. Mazurowski

The increasing prevalence of thyroid cancer globally has led to the development of various computer-aided detection methods. Accurate segmentation of thyroid nodules is a critical first step in the development of AI-assisted clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mahmoud El Hussieni

Social and behavioral determinants of health (SBDoH) have important roles in shaping people's health. In clinical research studies, especially comparative effectiveness studies, failure to adjust for SBDoH factors will potentially cause…

Computation and Language · Computer Science 2021-08-12 Zehao Yu , Xi Yang , Chong Dang , Songzi Wu , Prakash Adekkanattu , Jyotishman Pathak , Thomas J. George , William R. Hogan , Yi Guo , Jiang Bian , Yonghui Wu

Objective: To evaluate the accuracy, computational cost and portability of a new Natural Language Processing (NLP) method for extracting medication information from clinical narratives. Materials and Methods: We propose an original…

Population-based cancer registries depend on pathology reports as their primary diagnostic source, yet manual abstraction is resource-intensive and contributes to delays in cancer data. While transformer-based NLP systems have improved…

Computation and Language · Computer Science 2026-01-05 Jonathan Simkin , Lovedeep Gondara , Zeeshan Rizvi , Gregory Doyle , Jeff Dowden , Dan Bond , Desmond Martin , Raymond Ng

Objective: Fluoropyrimidines are widely prescribed for colorectal and breast cancers, but are associated with toxicities such as hand-foot syndrome and cardiotoxicity. Since toxicity documentation is often embedded in clinical notes, we…

Computation and Language · Computer Science 2025-10-24 Xizhi Wu , Madeline S. Kreider , Philip E. Empey , Chenyu Li , Yanshan Wang

In this study, we develop a new CAD system for accurate thyroid cancer classification with emphasis on feature extraction. Prior studies have shown that thyroid texture is important for segregating the thyroid ultrasound images into…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Saurabh Saini , Kapil Ahuja , Marc C. Steinbach , Thomas Wick

In recent times, Transformer-based language models are making quite an impact in the field of natural language processing. As relevant parallels can be drawn between biological sequences and natural languages, the models used in NLP can be…

Computation and Language · Computer Science 2025-12-25 Nimisha Ghosh , Daniele Santoni , Indrajit Saha , Giovanni Felici

Natural Language Processing (NLP) has witnessed a transformative leap with the advent of transformer-based architectures, which have significantly enhanced the ability of machines to understand and generate human-like text. This paper…

Computation and Language · Computer Science 2025-03-27 Tianhao Wu , Yu Wang , Ngoc Quach

Accurate detection of ultrasound nodules is essential for the early diagnosis and treatment of thyroid and breast cancers. However, this task remains challenging due to irregular nodule shapes, indistinct boundaries, substantial scale…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jingjing Wang , Zhuo Xiao , Xinning Yao , Bo Liu , Lijuan Niu , Xiangzhi Bai , Fugen Zhou