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The diagnosed cases of Breast cancer is increasing annually and unfortunately getting converted into a high mortality rate. Cancer, at the early stages, is hard to detect because the malicious cells show similar properties (density) as…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Deepti Ameta

Supervised deep learning has shown state-of-the-art performance for medical image segmentation across different applications, including histopathology and cancer research; however, the manual annotation of such data is extremely laborious.…

As an essential indicator for cancer progression and treatment response, tumor size is often measured following the response evaluation criteria in solid tumors (RECIST) guideline in CT slices. By marking each lesion with its longest axis…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Lianyu Zhou , Dong Wei , Donghuan Lu , Wei Xue , Liansheng Wang , Yefeng Zheng

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Predicting TNM stage is the major determinant of breast cancer prognosis and treatment. The essential part of TNM stage classification is whether the cancer has metastasized to the regional lymph nodes (N-stage). Pathologic N-stage…

Computer Vision and Pattern Recognition · Computer Science 2018-05-31 Byungjae Lee , Kyunghyun Paeng

Automated segmentation of tuberculosis (TB)-consistent lesions in chest X-rays (CXRs) using deep learning (DL) methods can help reduce radiologist effort, supplement clinical decision-making, and potentially result in improved patient…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Sivaramakrishnan Rajaraman , Feng Yang , Ghada Zamzmi , Peng Guo , Zhiyun Xue , Sameer K Antani

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

The segmentation of histopathological whole slide images into tumourous and non-tumourous types of tissue is a challenging task that requires the consideration of both local and global spatial contexts to classify tumourous regions…

In the clinical settings, during digital examination of histopathological slides, the pathologist annotate the slides by marking the rough boundary around the suspected tumour region. The marking or annotation is generally represented as a…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Suvidha Tripathi , Satish Kumar Singh

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Recent advances in deep learning have greatly facilitated the automated segmentation of ultrasound images, which is essential for nodule morphological analysis. Nevertheless, most existing methods depend on extensive and precise annotations…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Xingyue Zhao , Zhongyu Li , Xiangde Luo , Peiqi Li , Peng Huang , Jianwei Zhu , Yang Liu , Jihua Zhu , Meng Yang , Shi Chang , Jun Dong

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Precision medicine has the potential to revolutionize healthcare, but much of the data for patients is locked away in unstructured free-text, limiting research and delivery of effective personalized treatments. Generating large annotated…

Computation and Language · Computer Science 2020-12-16 Nick Altieri , Briton Park , Mara Olson , John DeNero , Anobel Odisho , Bin Yu

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Prostate cancer is one of the most prevalent malignancies in the world. While deep learning has potential to further improve computer-aided prostate cancer detection on MRI, its efficacy hinges on the exhaustive curation of manually…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Alex Chen , Nathan Lay , Stephanie Harmon , Kutsev Ozyoruk , Enis Yilmaz , Brad J. Wood , Peter A. Pinto , Peter L. Choyke , Baris Turkbey