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This paper deals with a problem which describes tuberculosis granuloma formation \begin{align*} \begin{cases} u_t = \Delta u - \nabla \cdot (u \nabla v) - uv - u + \beta, &x \in \Omega,\ t>0, \\ v_t = \Delta v + v -uv + \mu w, &x \in…

Analysis of PDEs · Mathematics 2026-03-06 Masaaki Mizukami , Yuya Tanaka

In this paper we consider the following Dirichlet problem for the $p$-Laplacian in the positive parameters $\lambda$ and $\beta$: [{{array} [c]{rcll}% -\Delta_{p}u & = & \lambda h(x,u)+\beta f(x,u,\nabla u) & \text{in}\Omega u & = & 0 &…

Analysis of PDEs · Mathematics 2013-03-28 Hamilton Bueno , Grey Ercole

We consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. The model is derived by taking the incompressible limit of porous medium type equations, and the boundary instability of this model was recently studied…

Analysis of PDEs · Mathematics 2025-05-13 Yu Feng , Qingyou He , Jian-Guo Liu , Zhennan Zhou

The dynamical and stationary behaviors of a fourth-order evolution equation with clamped boundary conditions and a singular nonlocal reaction term, which is coupled to an elliptic free boundary problem on a non-smooth domain, are…

Analysis of PDEs · Mathematics 2013-08-29 Philippe Laurencot , Christoph Walker

A free boundary value problem related to the genesis of multispecies granular biofilms is presented. The granular biofilm is modelled as a spherical free boundary domain with radial symmetry. The proposed model is conceived in the framework…

Analysis of PDEs · Mathematics 2023-01-31 F. Russo , M. R. Mattei , A. Tenore , B. D'Acunto , V. Luongo , L. Frunzo

We study a moving boundary problem describing the growth of nonnecrotic tumors in different regimes of vascularisation. This model consists of two decoupled Dirichlet problem, one for the rate at which nutrient is added to the tumor domain…

Analysis of PDEs · Mathematics 2010-03-05 Joachim Escher , Anca-Voichita Matioc

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

Analysis of PDEs · Mathematics 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

Let $\Omega \subset \mathbb{R}^N$, $N \geq 2$, be a smooth bounded domain. We consider the boundary value problem \begin{equation} \label{Plambda-Abstract-ch3} \tag{$P_{\lambda}$} -\Delta u = c_{\lambda}(x) u + \mu |\nabla u|^2 + h(x)\,,…

Analysis of PDEs · Mathematics 2019-09-12 Colette De Coster , Antonio J. Fernández

This paper is devoted to a complete characterization of the free boundary of all solutions to the following spectral $k$-partition problem with measure and inclusion constraints: \[ \inf \left\{\sum_{i=1}^k \lambda_1(\omega_i)\; : \;…

Analysis of PDEs · Mathematics 2026-01-15 Dario Mazzoleni , Makson S. Santos , Hugo Tavares

In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…

Analysis of PDEs · Mathematics 2018-02-05 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

We study the periodic boundary value problem associated with the second order nonlinear equation \begin{equation*} u'' + ( \lambda a^{+}(t) - \mu a^{-}(t) ) g(u) = 0, \end{equation*} where $g(u)$ has superlinear growth at zero and sublinear…

Classical Analysis and ODEs · Mathematics 2015-12-23 Alberto Boscaggin , Guglielmo Feltrin , Fabio Zanolin

This paper studies the following system of differential equations modeling tumor angiogenesis in a bounded smooth domain $\Omega \subset \mathbb{R}^N$ ($N=1,2$): $$\label{0} \left\{\begin{array}{ll} p_t=\Delta p-\nabla\cdotp…

Analysis of PDEs · Mathematics 2019-03-27 Peter Y. H. Pang , Yifu Wang

In this paper we prove existence of nonnegative bounded solutions for the non-autonomous prescribed mean curvature problem in non-parametric form on an open bounded domain $\Omega$ of $\mathbb{R}^N$. The mean curvature, that depends on the…

Analysis of PDEs · Mathematics 2024-06-10 Daniela Giachetti , Francescantonio Oliva , Francesco Petitta

We extend basic regularity of the free boundary of the obstacle problem to some classes of heterogeneous quasilinear elliptic operators with variable growth that includes, in particular, the $p(x)$-Laplacian. Under the assumption of…

Analysis of PDEs · Mathematics 2014-01-28 S. Challal , A. Lyaghfouri , J. F. Rodrigues , R. Teymurazyan

In this paper, we prove several regularity results for the heterogeneous, two-phase free boundary problems $\mathcal {J}_{\gamma}(u)=\int_{\Omega}\big(f(x,\nabla u)+\lambda_{+}…

Analysis of PDEs · Mathematics 2018-09-25 Jun Zheng

Let $\Omega$ be a smooth bounded domain in $\mathbb{R}^n$ ($n\geq 3$) such that $0\in\partial \Omega$. In this memoir, we consider issues of non-existence, existence, and multiplicity of variational solutions in $H_{1,0}^2(\Omega)$ for the…

Analysis of PDEs · Mathematics 2020-03-13 Nassif Ghoussoub , Saikat Mazumdar , Frédéric Robert

Let $\Omega \subset \mathbb R^N$, $N \geq 2$, be a smooth bounded domain. We consider a boundary value problem of the form $$-\Delta u = c_{\lambda}(x) u + \mu(x) |\nabla u|^2 + h(x), \quad u \in H^1_0(\Omega)\cap L^{\infty}(\Omega)$$ where…

Analysis of PDEs · Mathematics 2018-11-02 Colette De Coster , Antonio J. Fernández , Louis Jeanjean

By means of topological methods, we provide new results on the existence, non-existence, localization and multiplicity of nontrivial solutions for systems of perturbed Hammerstein integral equations. In order to illustrate our theoretical…

Classical Analysis and ODEs · Mathematics 2016-08-30 Filomena Cianciaruso , Gennaro Infante , Paolamaria Pietramala

A singularly perturbed free boundary problem arising from a real problem associated with a Radiographic Integrated Test Stand concerns a solution of the equation $\Delta u = f(u)$ in a domain $\Omega$ subject to constant boundary data,…

Analysis of PDEs · Mathematics 2024-01-23 Alaa Haj Ali , Dongsheng Li , Peiyong Wang

This paper investigates a class of $p$-obstacle problems with subcritical exponents having the form \begin{align} \mathrm{div}\left( a(x)|\nabla u|^{p-2}\nabla u\right) =m_1\chi_{\{u>0\}}-m_2u^{\lambda-1}\chi_{\{u>0\}} \ \text{in}\…

Analysis of PDEs · Mathematics 2026-03-25 Jing Yu , Jun Zheng