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We introduce two new methods for deterministic convex optimization problems: QCC (Quadratic Cuts for Convex optimization) and QB (Quadratic Bundle method). We prove the complexity of these methods for composite optimization problems which…

Optimization and Control · Mathematics 2024-10-02 Vincent Guigues , Adriana Washington

Quantum annealers can be used to solve many (possibly NP-hard) combinatorial optimization problems, by formulating them as quadratic unconstrained binary optimization (QUBO) problems or, equivalently, using the Ising formulation. In this…

Quantum Physics · Physics 2024-06-13 Alessandro Gherardi , Alberto Leporati

A quantum annealer heuristically minimizes quadratic unconstrained binary optimization (QUBO) problems, but is limited by the physical hardware in the size and density of the problems it can handle. We have developed a meta-heuristic solver…

Discrete Mathematics · Computer Science 2016-05-20 Gili Rosenberg , Mohammad Vazifeh , Brad Woods , Eldad Haber

This paper proposes a novel dispatch formulation for micro-mobility vehicles using a Quantum Annealer (QA). In recent years, QA has gained increasing attention as a high-performance solver for combinatorial optimization problems. Meanwhile,…

Quantum Physics · Physics 2026-01-30 Takeru Goto , Masayuki Ohzeki

Analytical and practical evidence indicates the advantage of quantum computing solutions over classical alternatives. Quantum-based heuristics relying on the variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2023-01-05 Sarthak Gupta , Vassilis Kekatos

We introduce a quantum algorithm integrating counterdiabatic (CD) protocols with quantum Lyapunov control (QLC) to tackle combinatorial optimization problems. This approach offers versatility, allowing implementation as either a…

Quantum Physics · Physics 2024-09-20 Pranav Chandarana , Koushik Paul , Kasturi Ranjan Swain , Xi Chen , Adolfo del Campo

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

A multiple knapsack constraint over a set of items is defined by a set of bins of arbitrary capacities, and a weight for each of the items. An assignment for the constraint is an allocation of subsets of items to the bins which adheres to…

Data Structures and Algorithms · Computer Science 2021-06-29 Yaron Fairstein , Ariel Kulik , Hadas Shachnai

In this article, we introduce and study the Quadratic Bin Packing Problem (QBPP), which generalizes the classical bin packing problem by introducing a fixed cost for each used bin and a pairwise cost (or profit) incurred whenever two items…

Optimization and Control · Mathematics 2026-04-06 Vítor Gomes Chagas , Alberto Locatelli , Flávio Keidi Miyazawa , Manuel Iori

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

This tutorial offers a quick, hands-on introduction to solving Quadratic Unconstrained Binary Optimization (QUBO) models on currently available quantum computers and their simulators. We cover both IBM and D-Wave machines: IBM utilizes a…

Quantum Physics · Physics 2025-06-18 Arul Mazumder , Sridhar Tayur

Deep neural networks (DNNs) have been used to model complex optimization problems in many applications, yet have difficulty guaranteeing solution optimality and feasibility, despite training on large datasets. Training a NN as a surrogate…

Optimization and Control · Mathematics 2025-10-29 Fuat Can Beylunioglu , P. Robert Duimering , Mehrdad Pirnia

Quantum annealing has great promise in leveraging quantum mechanics to solve combinatorial optimisation problems. However, to realize this promise to it's fullest extent we must appropriately leverage the underlying physics. In this spirit,…

Quantum Physics · Physics 2020-12-10 Nicholas Chancellor

We benchmark the 5000+ qubit system Advantage coupled with the Hybrid Solver Service 2 released by D-Wave Systems Inc. in September 2020 by using a new class of optimization problems called garden optimization problems known in companion…

Quantum Physics · Physics 2021-09-28 Carlos D. Gonzalez Calaza , Dennis Willsch , Kristel Michielsen

In this paper, we propose a novel trajectory optimization algorithm for mobile manipulators under end-effector path, collision avoidance and various kinematic constraints. Our key contribution lies in showing how this highly non-linear and…

Robotics · Computer Science 2019-04-23 Arun Kumar Singh , Andrei Ahonen , Reza Ghabcheloo , Andreas Muller

Finding shape correspondences can be formulated as an NP-hard quadratic assignment problem (QAP) that becomes infeasible for shapes with high sampling density. A promising research direction is to tackle such quadratic optimization problems…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Marcel Seelbach Benkner , Zorah Lähner , Vladislav Golyanik , Christof Wunderlich , Christian Theobalt , Michael Moeller

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

We address the classical knapsack problem and a variant in which an upper bound is imposed on the number of items that can be selected. We show that appropriate combinations of rounding techniques yield novel and powerful ways of rounding.…

Computational Complexity · Computer Science 2007-05-23 Monaldo Mastrolilli , Marcus Hutter

Many real-world optimization problems have multiple interacting components. Each of these can be NP-hard and they can be in conflict with each other, i.e., the optimal solution for one component does not necessarily represent an optimal…

Neural and Evolutionary Computing · Computer Science 2021-09-13 Jonatas B. C. Chagas , Markus Wagner

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos