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We introduce a counterdiabatic (CD) extension of the Quantum Approximate Optimization Algorithm (QAOA) for constrained portfolio optimization. By incorporating approximate adiabatic gauge potentials generated from nested commutators of the…

Quantum Physics · Physics 2026-05-11 Jose Falla , Ilya Safro

Clustering is one of the most fundamental tools in data science and machine learning, and k-means clustering is one of the most common such methods. There is a variety of approximate algorithms for the k-means problem, but computing the…

Optimization and Control · Mathematics 2024-02-22 Martin Ryner , Jan Kronqvist , Johan Karlsson

Portfolio optimization is a fundamental problem in finance that aims to determine the optimal allocation of assets within a portfolio to maximize returns while minimizing risk. It can be formulated as a Quadratic Unconstrained Binary…

Quantum Physics · Physics 2025-08-27 Anbang Wang , Zhonggang Lv , Zhenyuan Ma , Dunbo Cai , Zhihong Zhang

Molecular docking (MD) is a crucial task in drug design, which predicts the position, orientation, and conformation of the ligand when bound to a target protein. It can be interpreted as a combinatorial optimization problem, where quantum…

Chemical Physics · Physics 2024-04-15 Yunting Li , Xiaopeng Cui , Zhaoping Xiong , Bowen Liu , Bi-Ying Wang , Runqiu Shu , Nan Qiao , Man-Hong Yung

In this paper, we consider the nonconvex quadratically constrained quadratic programming (QCQP) with one quadratic constraint. By employing the conjugate gradient method, an efficient algorithm is proposed to solve QCQP that exploits the…

Optimization and Control · Mathematics 2018-07-17 Akram Taati , Maziar Salahi

For e-commerce websites, deciding the manner in which items are listed on webpages is an important issue because it can dramatically affect item sales. One of the simplest strategies of listing items to improve the overall sales is to do so…

Quantum Physics · Physics 2019-07-17 Naoki Nishimura , Kotaro Tanahashi , Koji Suganuma , Masamichi J. Miyama , Masayuki Ohzeki

The recent availability of quantum annealers as cloud-based services has enabled new ways to handle machine learning problems, and several relevant algorithms have been adapted to run on these devices. In a recent work, linear regression…

Quantum Physics · Physics 2025-03-18 Costantino Carugno , Maurizio Ferrari Dacrema , Paolo Cremonesi

The multiple knapsack problem with grouped items aims to maximize rewards by assigning groups of items among multiple knapsacks, considering knapsack capacities. Either all items in a group are assigned or none at all. We propose algorithms…

Data Structures and Algorithms · Computer Science 2020-06-02 Francisco Castillo-Zunino , Pinar Keskinocak

We present a classical algorithm to find approximate solutions to instances of quadratic unconstrained binary optimisation. The algorithm can be seen as an analogue of quantum annealing under the restriction of a product state space, where…

Quantum Physics · Physics 2023-02-14 Joseph Bowles , Alexandre Dauphin , Patrick Huembeli , José Martinez , Antonio Acín

Molecular docking, which aims to find the most stable interacting configuration of a set of molecules, is of critical importance to drug discovery. Although a considerable number of classical algorithms have been developed to carry out…

Biomolecules · Quantitative Biology 2022-10-21 Mohit Pandey , Tristan Zaborniak , Hans Melo , Alexey Galda , Vikram K. Mulligan

Hybrid quantum-classical algorithms such as the Quantum Approximate Optimization Algorithm (QAOA) are considered as one of the most encouraging approaches for taking advantage of near-term quantum computers in practical applications. Such…

The Alternating Direction Method of Multipliers (ADMM) has gained significant attention across a broad spectrum of machine learning applications. Incorporating the over-relaxation technique shows potential for enhancing the convergence rate…

Optimization and Control · Mathematics 2024-01-02 Jintao Song , Wenqi Lu , Yunwen Lei , Yuchao Tang , Zhenkuan Pan , Jinming Duan

Advances in quantum algorithms suggest a tentative scaling advantage on certain combinatorial optimization problems. Recent work, however, has also reinforced the idea that barren plateaus render variational algorithms ineffective on large…

Quantum Physics · Physics 2025-03-14 Tim Bode , Krish Ramesh , Tobias Stollenwerk

We study the three-dimensional Knapsack (3DK) problem, in which we are given a set of axis-aligned cuboids with associated profits and an axis-aligned cube knapsack. The objective is to find a non-overlapping axis-aligned packing (by…

Data Structures and Algorithms · Computer Science 2025-03-26 Klaus Jansen , Debajyoti Kar , Arindam Khan , K. V. N. Sreenivas , Malte Tutas

Submodular maximization problems belong to the family of combinatorial optimization problems and enjoy wide applications. In this paper, we focus on the problem of maximizing a monotone submodular function subject to a $d$-knapsack…

Machine Learning · Computer Science 2016-07-06 Qilian Yu , Easton Li Xu , Shuguang Cui

Constrained binary optimization aims to find an optimal assignment to minimize or maximize the objective meanwhile satisfying the constraints, which is a representative NP problem in various domains, including transportation, scheduling,…

Quantum Physics · Physics 2025-08-18 Debin Xiang , Qifan Jiang , Liqiang Lu , Siwei Tan , Jianwei Yin

There is growing interest in solving computer vision problems such as mesh or point set alignment using Adiabatic Quantum Computing (AQC). Unfortunately, modern experimental AQC devices such as D-Wave only support Quadratic Unconstrained…

Optimization problems is one of the most challenging applications of quantum computers, as well as one of the most relevants. As a consequence, it has attracted huge efforts to obtain a speedup over classical algorithms using quantum…

Quantum annealers of D-Wave Systems, Inc., offer an efficient way to compute high quality solutions of NP-hard problems. This is done by mapping a problem onto the physical qubits of the quantum chip, from which a solution is obtained after…

Quantum Physics · Physics 2022-11-30 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

We study the task of finding good local optima in combinatorial optimization problems. Although combinatorial optimization is NP-hard in general, locally optimal solutions are frequently used in practice. Local search methods however…

Machine Learning · Statistics 2020-01-03 Uri Patish , Shimon Ullman
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