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Biological systems are characterized by the ubiquitous roles of weak, that is, non-covalent molecular interactions, small, often very small, numbers of specific molecules per cell, and Brownian motion. These combine to produce stochastic…

Cell Behavior · Quantitative Biology 2023-04-27 Michael W. Klymkowsky

This paper introduces a novel approach to quantifying ecological resilience in biological systems, particularly focusing on noisy systems responding to episodic disturbances with sudden adaptations. Incorporating concepts from…

Quantitative Methods · Quantitative Biology 2024-12-24 Jorge M. Ramirez , Juan M. Restrepo , Valerio Lucarini , David Weston

If two species exhibit different nonlinear responses to a single shared resource, and if each species modifies the resource dynamics such that this favors its competitor, they may stably coexist. This coexistence mechanism, known as…

Populations and Evolution · Quantitative Biology 2015-06-16 Florian Hartig , Tamara Münkemüller , Karin Johst , Ulf Dieckmann

The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…

Populations and Evolution · Quantitative Biology 2026-04-30 Leonardo Ivan Estrella Dzib , James Holehouse

Chaos, or exponential sensitivity to small perturbations, appears everywhere in nature. Moreover, chaos is predicted to play diverse functional roles in living systems. A method for detecting chaos from empirical measurements should…

Quantitative Methods · Quantitative Biology 2020-01-13 Daniel Toker , Friedrich T. Sommer , Mark D'Esposito

A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction. Diversification, formation of discrete and recursive types, and…

chao-dyn · Physics 2009-10-31 Kunihiko Kaneko , Chikara Furusawa

Search for possible relationships between phylogeny and ontogeny is one of the most important issues in the field of evolutionary developmental biology. By representing developmental dynamics of spatially located cells with gene expression…

Populations and Evolution · Quantitative Biology 2015-04-01 Takahiro Kohsokabe , Kunihiko Kaneko

Noise, through its interaction with the nonlinearity of the living systems, can give rise to counter-intuitive phenomena such as stochastic resonance, noise-delayed extinction, temporal oscillations, and spatial patterns. In this paper we…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Spagnolo , D. Valenti , A. Fiasconaro

We undertake a systematic study of the dynamics of Boolean networks to determine the origin of chaos observed in recent experiments. Networks with nodes consisting of ideal logic gates are known to display either steady states, periodic…

Chaotic Dynamics · Physics 2015-05-14 Hugo L. D. de S. Cavalcante , Daniel J. Gauthier , Joshua E. S. Socolar , Rui Zhang

A full accounting of biological robustness remains elusive; both in terms of the mechanisms by which robustness is achieved and the forces that have caused robustness to grow over evolutionary time. Although its importance to topics such as…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James Whitacre , Axel Bender

In dynamic systems that adapt to users' needs and changing environments, dependability needs cannot be avoided. This paper proposes an orthogonal fault tolerance model as a means to manage and reason about multiple fault tolerance…

Software Engineering · Computer Science 2014-04-29 Sobia K Khan

Noise is typically treated as the adversary of quantum information processing. For open quantum dynamics, however, dissipation is part of the target physics, creating a tension with fault-tolerant architectures designed to suppress…

Quantum Physics · Physics 2026-05-29 Sameer Dambal , Michael AD Taylor , Yu Zhang

Large-scale decentralized systems of autonomous agents interacting via asynchronous communication often experience the following self-healing dilemma: fault detection inherits network uncertainties making a remote faulty process…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-25 Jovan Nikolic , Nursultan Jubatyrov , Evangelos Pournaras

Robustness and evolvability are essential properties to the evolution of biological networks. To determine if a biological network is robust and/or evolvable, it is required to compare its functions before and after mutations. However, this…

Adaptation and Self-Organizing Systems · Physics 2025-12-22 Hyobin Kim , Stalin Muñoz , Pamela Osuna , Carlos Gershenson

Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system…

Molecular Networks · Quantitative Biology 2008-09-18 Vahid Shahrezaei , Julien F Ollivier , Peter S Swain

Modularisation, repetition, and symmetry are structural features shared by almost all biological neural networks. These features are very unlikely to be found by the means of structural evolution of artificial neural networks. This paper…

Neural and Evolutionary Computing · Computer Science 2017-01-19 Keyan Ghazi-Zahedi

In biology, the evolution of increasingly cooperative groups has shaped the history of life. Genes collaborate in the control of cells; cells efficiently divide tasks to produce cohesive multicellular individuals; individual members of…

Populations and Evolution · Quantitative Biology 2011-12-15 Steven A. Frank

By default neural networks are not robust to changes in data distribution. This has been demonstrated with simple image corruptions, such as blurring or adding noise, degrading image classification performance. Many methods have been…

Machine Learning · Computer Science 2023-06-16 Ian Mason , Anirban Sarkar , Tomotake Sasaki , Xavier Boix

Robust stability and stochastic stability have separately seen intense study in control theory for many decades. In this work we establish relations between these properties for discrete-time systems and employ them for robust control…

Dynamical Systems · Mathematics 2020-04-20 Benjamin Gravell , Peyman Mohajerin Esfahani , Tyler Summers

A major obstacle towards realizing a practical quantum computer is the noise that arises due to system-environment interactions. While it is very well known that quantum error correction (QEC) provides a way to protect against errors that…

Quantum Physics · Physics 2023-02-24 Akshaya Jayashankar