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Fisher Discriminant Analysis (FDA) is a subspace learning method which minimizes and maximizes the intra- and inter-class scatters of data, respectively. Although, in FDA, all the pairs of classes are treated the same way, some classes are…

Machine Learning · Statistics 2020-07-01 Benyamin Ghojogh , Milad Sikaroudi , H. R. Tizhoosh , Fakhri Karray , Mark Crowley

Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors. Preoperative…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Zhilin Zheng , Xu Fang , Jiawen Yao , Mengmeng Zhu , Le Lu , Lingyun Huang , Jing Xiao , Yu Shi , Hong Lu , Jianping Lu , Ling Zhang , Chengwei Shao , Yun Bian

In this work, we develop analysis and algorithms for a class of (stochastic) bilevel optimization problems whose lower-level (LL) problem is strongly convex and linearly constrained. Most existing approaches for solving such problems rely…

Optimization and Control · Mathematics 2025-04-08 Prashant Khanduri , Ioannis Tsaknakis , Yihua Zhang , Sijia Liu , Mingyi Hong

Diffuse Reflectance Spectroscopy has demonstrated a strong aptitude for identifying and differentiating biological tissues. However, the broadband and smooth nature of these signals require algorithmic processing, as they are often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Nicola Rossberg , Celina L. Li , Simone Innocente , Stefan Andersson-Engels , Katarzyna Komolibus , Barry O'Sullivan , Andrea Visentin

High-dimensional data that evolve dynamically feature predominantly in the modern data era. As a partial response to this, recent years have seen increasing emphasis to address the dimensionality challenge. However, the non-static nature of…

Methodology · Statistics 2019-01-21 Binyan Jiang , Ziqi Chen , Chenlei Leng

Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and extensive heterogeneity across subtypes. Current diagnostic methods are limited in their ability to reveal underlying genomic…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Gabriela Fernandes

Decentralized machine learning is a promising emerging paradigm in view of global challenges of data ownership and privacy. We consider learning of linear classification and regression models, in the setting where the training data is…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-20 Lie He , An Bian , Martin Jaggi

Pairwise difference learning (PDL) has recently been introduced as a new meta-learning technique for regression. Instead of learning a mapping from instances to outcomes in the standard way, the key idea is to learn a function that takes…

Machine Learning · Computer Science 2024-07-01 Mohamed Karim Belaid , Maximilian Rabus , Eyke Hüllermeier

The objectives of this "perspective" paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to discuss how these might be used to develop tools to advance…

Quantitative Methods · Quantitative Biology 2015-06-18 Mathukumalli Vidyasagar

Convolutional neural networks (CNNs) are one of the most effective deep learning methods to solve image classification problems, but the best architecture of a CNN to solve a specific problem can be extremely complicated and hard to design.…

Neural and Evolutionary Computing · Computer Science 2018-03-20 Bin Wang , Yanan Sun , Bing Xue , Mengjie Zhang

Frozen pretrained image representations are widely used for transfer learning: a backbone is kept fixed, feature vectors are extracted, and a lightweight classifier is trained on top. This pipeline usually feeds the full feature vector to…

Machine Learning · Computer Science 2026-05-12 Indar Kumar , Girish Karhana , Sai Krishna Jasti , Ankit Hemant Lade

Low-dose computed tomography (LDCT) aims to minimize the radiation exposure to patients while maintaining diagnostic image quality. However, traditional CT reconstruction algorithms often struggle with the ill-posed nature of the problem,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Daisy Chen

Acoustic models using probabilistic linear discriminant analysis (PLDA) capture the correlations within feature vectors using subspaces which do not vastly expand the model. This allows high dimensional and correlated feature spaces to be…

Computation and Language · Computer Science 2015-06-23 Liang Lu , Steve Renals

Real-world structural optimisation problems involve multiple loading conditions and design constraints, with responses typically depending on states of discretised governing equations. Generally, one uses gradient-based nested analysis and…

Computational Engineering, Finance, and Science · Computer Science 2022-02-23 Stijn Koppen , Max van der Kolk , Sanne van den Boom , Matthijs Langelaar

Given a gene expression data array of a list of bladder cancer patients with their tumor states, it may be difficult to determine which genes can operate as disease markers when the array is large and possibly contains outliers and missing…

The combination of Monte Carlo methods and deep learning has recently led to efficient algorithms for solving partial differential equations (PDEs) in high dimensions. Related learning problems are often stated as variational formulations…

Machine Learning · Computer Science 2022-08-08 Lorenz Richter , Julius Berner

Liver infection is a common disease, which poses a great threat to human health, but there is still able to identify an optimal technique that can be used on large-level screening. This paper deals with ML algorithms using different data…

Machine Learning · Computer Science 2023-05-16 P. Deivendran , S. Selvakanmani , S. Jegadeesan , V. Vinoth Kumar

Quantum computing has the potential to speed up some optimization methods. One can use quantum computers to solve linear systems via Quantum Linear System Algorithms (QLSAs). QLSAs can be used as a subroutine for algorithms that require…

Optimization and Control · Mathematics 2024-12-23 Zeguan Wu , Pouya Sampourmahani , Mohammadhossein Mohammadisiahroudi , Tamás Terlaky

Several studies point out different causes of performance degradation in supervised machine learning. Problems such as class imbalance, overlapping, small-disjuncts, noisy labels, and sparseness limit accuracy in classification algorithms.…

Machine Learning · Computer Science 2020-04-17 Gustavo A. Valencia-Zapata , Carolina Gonzalez-Canas , Michael G. Zentner , Okan Ersoy , Gerhard Klimeck

Linear and Quadratic Discriminant Analysis (LDA and QDA) are well-known classical methods but can heavily suffer from non-Gaussian distributions and/or contaminated datasets, mainly because of the underlying Gaussian assumption that is not…

Machine Learning · Statistics 2023-07-06 Pierre Houdouin , Matthieu Jonckheere , Frederic Pascal