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We develop and analyze explainable machine learning (ML) models for sepsis outcome prediction using a novel Electronic Health Record (EHR) dataset from 12,286 hospitalizations at a large emergency hospital in Romania. The dataset includes…

Machine Learning · Computer Science 2026-04-07 Andrei-Alexandru Bunea , Ovidiu Ghibea , Dan-Matei Popovici , Ion Daniel , Octavian Andronic

Background: While machine learning (ML) models are rapidly emerging as promising screening tools in critical care medicine, the identification of homogeneous subphenotypes within populations with heterogeneous conditions such as pediatric…

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

Machine Learning · Computer Science 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Hospital readmission, defined as patients being re-hospitalized shortly after discharge, is a critical concern as it impacts patient outcomes and healthcare costs. Identifying patients at risk of readmission allows for timely interventions,…

Computation and Language · Computer Science 2024-04-09 Rasoul Samani , Mohammad Dehghani , Fahime Shahrokh

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

Machine Learning · Computer Science 2025-11-11 Atharva Thakur , Shruti Dhumal

Process mining is increasingly adopted in modern organizations, producing numerous process models that, while valuable, can lead to model overload and decision-making complexity. This paper explores a multi-criteria decision-making (MCDM)…

Computers and Society · Computer Science 2025-06-12 Rob H. Bemthuis

The Model Checking Integrated Planning System (MIPS) is a temporal least commitment heuristic search planner based on a flexible object-oriented workbench architecture. Its design clearly separates explicit and symbolic directed exploration…

Artificial Intelligence · Computer Science 2011-07-04 S. Edelkamp

Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection…

Human-Computer Interaction · Computer Science 2024-02-27 Shao Zhang , Jianing Yu , Xuhai Xu , Changchang Yin , Yuxuan Lu , Bingsheng Yao , Melanie Tory , Lace M. Padilla , Jeffrey Caterino , Ping Zhang , Dakuo Wang

Process mining is a technique that performs an automatic analysis of business processes from a log of events with the promise of understanding how processes are executed in an organisation. Several models have been proposed to address this…

Artificial Intelligence · Computer Science 2015-03-26 Catarina Moreira

In recent years, process mining emerged as a proven technology to analyze and improve operational processes. An expanding range of organizations using process mining in their daily operation brings a broader spectrum of processes to be…

Machine Learning · Computer Science 2023-11-07 Viki Peeva , Wil M. P. van der Aalst

This paper presents an approach of using methods of process mining and rule-based artificial intelligence to analyze and understand study paths of students based on campus management system data and study program models. Process mining…

Process analytics approaches allow organizations to support the practice of Business Process Management and continuous improvement by leveraging all process-related data to extract knowledge, improve process performance and support…

Other Computer Science · Computer Science 2025-02-25 Asjad Khan , Aditya Ghose , Hoa Dam , Arsal Syed

The Product Data Model (PDM) is an example of a data-centric approach to modelling information-intensive business processes, which offers exibility and facilitates process optimization. Because the approach is declarative in nature, there…

Databases · Computer Science 2022-05-19 Konstantinos Varvoutas , Anastasios Gounaris , Georgia Kougka , Hajo A. Reijers

Predicting critical health outcomes such as patient mortality and hospital readmission is essential for improving survivability. However, healthcare datasets have many concurrences that create complexities, leading to poor predictions.…

Machine Learning · Computer Science 2024-07-04 Negin Ashrafi , Armin Abdollahi , Greg Placencia , Maryam Pishgar

We present a case study of Process Mining (PM) for personnel security screening in the Canadian government. We consider customer (process time) and organizational (cost) perspectives. Furthermore, in contrast to most published case studies,…

Computers and Society · Computer Science 2024-09-11 Jacques Trottier , William Van Woensel , Xiaoyang Wang , Kavya Mallur , Najah El-Gharib , Daniel Amyot

Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this…

Numerous process discovery techniques exist for generating process models that describe recorded executions of business processes. The models are meant to generalize executions into human-understandable modeling patterns, notably…

Software Engineering · Computer Science 2021-09-15 Dennis Brons , Roeland Scheepens , Dirk Fahland

One of the most valuable assets of an organization is its organizational data. The analysis and mining of this potential hidden treasure can lead to much added-value for the organization. Process mining is an emerging area that can be…

Software Engineering · Computer Science 2016-07-05 Asef Pourmasoumi , Ebrahim Bagheri

Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…

Machine Learning · Computer Science 2020-10-16 Michael Moor , Max Horn , Bastian Rieck , Damian Roqueiro , Karsten Borgwardt