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The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

Process mining involves discovering, monitoring, and improving real processes by extracting knowledge from event logs in information systems. Process mining has become an important topic in recent years, as evidenced by a growing number of…

Software Engineering · Computer Science 2021-04-01 Sabah Al-Fedaghi

The recent increase in the availability of medical data, possible through automation and digitization of medical equipment, has enabled more accurate and complete analysis on patients' medical data through many branches of data science. In…

The global issue of overcrowding in emergency departments (ED) necessitates the analysis of patient flow through ED to enhance efficiency and alleviate overcrowding. However, traditional analytical methods are time-consuming and costly. The…

Databases · Computer Science 2025-05-27 Jia Wei , Chun Ouyang , Bemali Wickramanayake , Zhipeng He , Keshara Perera , Catarina Moreira

Sepsis is a life-threatening condition caused by the body's response to an infection. In order to treat patients with sepsis, physicians must control varying dosages of various antibiotics, fluids, and vasopressors based on a large number…

Machine Learning · Computer Science 2019-12-17 Amirhossein Kiani , Chris Wang , Angela Xu

The discipline of process mining has a solid track record of successful applications to the healthcare domain. Within such research space, we conducted a case study related to the Intensive Care Unit (ICU) ward of the Uniklinik Aachen…

ERP systems contain huge amounts of data related to the actual execution of business processes. These systems have a particular way of recording activities which results in an unclear display of business processes in event logs. Several…

Databases · Computer Science 2013-12-10 S. Hanumanth Sastry , Prof. M. S. Prasada Babu

Sepsis accounts for more than 50% of hospital deaths, and the associated cost ranks the highest among hospital admissions in the US. Improved understanding of disease states, severity, and clinical markers has the potential to significantly…

Quantitative Methods · Quantitative Biology 2022-10-11 Chih-Hao Fang , Vikram Ravindra , Salma Akhter , Mohammad Adibuzzaman , Paul Griffin , Shankar Subramaniam , Ananth Grama

Process Mining has recently gained popularity in healthcare due to its potential to provide a transparent, objective and data-based view on processes. Conformance checking is a sub-discipline of process mining that has the potential to…

Artificial Intelligence · Computer Science 2020-10-23 An Nguyen , Wenyu Zhang , Leo Schwinn , Bjoern Eskofier

Process mining has emerged as a powerful analytical technique for understanding complex healthcare workflows. However, its application faces significant barriers, including technical complexity, a lack of standardized approaches, and…

Artificial Intelligence · Computer Science 2026-02-11 Eduardo Illueca-Fernandez , Kaile Chen , Fernando Seoane , Farhad Abtahi

Computer-based scientific experiments are becoming increasingly data-intensive, necessitating the use of High-Performance Computing (HPC) clusters to handle large scientific workflows. These workflows result in complex data and control…

Databases · Computer Science 2025-02-17 Zahra Sadeghibogar , Alessandro Berti , Marco Pegoraro , Wil M. P. van der Aalst

Sepsis is a life-threatening condition triggered by an extreme infection response. Our objective is to forecast sepsis patient outcomes using their medical history and treatments, while learning interpretable state representations to assess…

Machine Learning · Computer Science 2023-11-17 Anna Wong , Shu Ge , Nassim Oufattole , Adam Dejl , Megan Su , Ardavan Saeedi , Li-wei H. Lehman

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

Machine Learning · Computer Science 2019-03-07 Avijit Mitra , Khalid Ashraf

Background Sepsis is one of the most life-threatening circumstances for critically ill patients in the US, while a standardized criteria for sepsis identification is still under development. Disparities in social determinants of sepsis…

Machine Learning · Computer Science 2021-12-16 Hanyin Wang , Yikuan Li , Andrew Naidech , Yuan Luo

Process mining is a field of computer science that deals with discovery and analysis of process models based on automatically generated event logs. Currently, many companies use this technology for optimization and improving their…

Artificial Intelligence · Computer Science 2023-03-27 Antonina K. Begicheva , Irina A. Lomazova , Roman A. Nesterov

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Process mining techniques help to improve processes using event data. Such data are widely available in information systems. However, they often contain highly sensitive information. For example, healthcare information systems record event…

Databases · Computer Science 2021-05-26 Majid Rafiei , Wil M. P. van der Aalst

Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

Process mining provides techniques to improve the performance and compliance of operational processes. Although sometimes the term "workflow mining" is used, the application in the context of Workflow Management (WFM) and Business Process…

Software Engineering · Computer Science 2020-09-15 Alessandro Berti , Wil van der Aalst , David Zang , Magdalena Lang