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Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Medical Image Analysis is currently experiencing a paradigm shift due to Deep Learning. This technology has recently attracted so much interest of the Medical Imaging community that it led to a specialized conference in `Medical Imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-18 Fouzia Altaf , Syed M. S. Islam , Naveed Akhtar , Naeem K. Janjua

Machine Learning (ML) models are extensively used in various applications due to their significant advantages over traditional learning methods. However, the developed ML models often underperform when deployed in the real world due to the…

Machine Learning · Computer Science 2025-11-05 Abdullah Almansour , Ozan Tonguz

Recently, there has been great progress in the ability of artificial intelligence (AI) algorithms to classify dermatological conditions from clinical photographs. However, little is known about the robustness of these algorithms in…

One of the critical challenges in machine learning applications is to have fair predictions. There are numerous recent examples in various domains that convincingly show that algorithms trained with biased datasets can easily lead to…

Machine Learning · Computer Science 2020-06-18 Samaneh Abbasi-Sureshjani , Ralf Raumanns , Britt E. J. Michels , Gerard Schouten , Veronika Cheplygina

The use of machine learning to develop intelligent software tools for interpretation of radiology images has gained widespread attention in recent years. The development, deployment, and eventual adoption of these models in clinical…

Machine Learning · Computer Science 2021-02-04 Viraj Kulkarni , Manish Gawali , Amit Kharat

Deep Learning (DL) requires a large amount of training data to provide quality outcomes. However, the field of medical imaging suffers from the lack of sufficient data for properly training DL models because medical images require manual…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Laith Alzubaidi , J. Santamaría , Mohamed Manoufali , Beadaa Mohammed , Mohammed A. Fadhel , Jinglan Zhang , Ali H. Al-Timemy , Omran Al-Shamma , Ye Duan

The success of deep learning has set new benchmarks for many medical image analysis tasks. However, deep models often fail to generalize in the presence of distribution shifts between training (source) data and test (target) data. One…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Dwarikanath Mahapatra

Vision-language models (VLMs) are gaining attention in medical image analysis. These are pre-trained on large, heterogeneous data sources, yielding rich and transferable representations. Notably, the combination of modality-specialized VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Julio Silva-Rodríguez , Fereshteh Shakeri , Houda Bahig , Jose Dolz , Ismail Ben Ayed

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

Saliency maps have become a widely used method to make deep learning models more interpretable by providing post-hoc explanations of classifiers through identification of the most pertinent areas of the input medical image. They are…

It is an open secret that ImageNet is treated as the panacea of pretraining. Particularly in medical machine learning, models not trained from scratch are often finetuned based on ImageNet-pretrained models. We posit that pretraining on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Frederic Jonske , Moon Kim , Enrico Nasca , Janis Evers , Johannes Haubold , René Hosch , Felix Nensa , Michael Kamp , Constantin Seibold , Jan Egger , Jens Kleesiek

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

In recent years the development of artificial intelligence (AI) systems for automated medical image analysis has gained enormous momentum. At the same time, a large body of work has shown that AI systems can systematically and unfairly…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 María Agustina Ricci Lara , Candelaria Mosquera , Enzo Ferrante , Rodrigo Echeveste

Estimating the prevalence of a category in a population using imperfect measurement devices (diagnostic tests, classifiers, or large language models) is fundamental to science, public health, and online trust and safety. Standard approaches…

Artificial Intelligence · Computer Science 2026-04-24 Fridolin Linder , Thomas Leeper , Daniel Haimovich , Niek Tax , Lorenzo Perini , Milan Vojnovic

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

Domain adaptation (DA) techniques have the potential in machine learning to alleviate distribution differences between training and test sets by leveraging information from source domains. In image classification, most advances in DA have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Ahmad Chaddad , Yihang Wu , Reem Kateb , Christian Desrosiers

We consider robustness to distribution shifts in the context of diagnostic models in healthcare, where the prediction target $Y$, e.g., the presence of a disease, is causally upstream of the observations $X$, e.g., a biomarker. Distribution…

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Matthias Eisenmann , Annika Reinke , Vivienn Weru , Minu Dietlinde Tizabi , Fabian Isensee , Tim J. Adler , Patrick Godau , Veronika Cheplygina , Michal Kozubek , Sharib Ali , Anubha Gupta , Jan Kybic , Alison Noble , Carlos Ortiz de Solórzano , Samiksha Pachade , Caroline Petitjean , Daniel Sage , Donglai Wei , Elizabeth Wilden , Deepak Alapatt , Vincent Andrearczyk , Ujjwal Baid , Spyridon Bakas , Niranjan Balu , Sophia Bano , Vivek Singh Bawa , Jorge Bernal , Sebastian Bodenstedt , Alessandro Casella , Jinwook Choi , Olivier Commowick , Marie Daum , Adrien Depeursinge , Reuben Dorent , Jan Egger , Hannah Eichhorn , Sandy Engelhardt , Melanie Ganz , Gabriel Girard , Lasse Hansen , Mattias Heinrich , Nicholas Heller , Alessa Hering , Arnaud Huaulmé , Hyunjeong Kim , Bennett Landman , Hongwei Bran Li , Jianning Li , Jun Ma , Anne Martel , Carlos Martín-Isla , Bjoern Menze , Chinedu Innocent Nwoye , Valentin Oreiller , Nicolas Padoy , Sarthak Pati , Kelly Payette , Carole Sudre , Kimberlin van Wijnen , Armine Vardazaryan , Tom Vercauteren , Martin Wagner , Chuanbo Wang , Moi Hoon Yap , Zeyun Yu , Chun Yuan , Maximilian Zenk , Aneeq Zia , David Zimmerer , Rina Bao , Chanyeol Choi , Andrew Cohen , Oleh Dzyubachyk , Adrian Galdran , Tianyuan Gan , Tianqi Guo , Pradyumna Gupta , Mahmood Haithami , Edward Ho , Ikbeom Jang , Zhili Li , Zhengbo Luo , Filip Lux , Sokratis Makrogiannis , Dominik Müller , Young-tack Oh , Subeen Pang , Constantin Pape , Gorkem Polat , Charlotte Rosalie Reed , Kanghyun Ryu , Tim Scherr , Vajira Thambawita , Haoyu Wang , Xinliang Wang , Kele Xu , Hung Yeh , Doyeob Yeo , Yixuan Yuan , Yan Zeng , Xin Zhao , Julian Abbing , Jannes Adam , Nagesh Adluru , Niklas Agethen , Salman Ahmed , Yasmina Al Khalil , Mireia Alenyà , Esa Alhoniemi , Chengyang An , Talha Anwar , Tewodros Weldebirhan Arega , Netanell Avisdris , Dogu Baran Aydogan , Yingbin Bai , Maria Baldeon Calisto , Berke Doga Basaran , Marcel Beetz , Cheng Bian , Hao Bian , Kevin Blansit , Louise Bloch , Robert Bohnsack , Sara Bosticardo , Jack Breen , Mikael Brudfors , Raphael Brüngel , Mariano Cabezas , Alberto Cacciola , Zhiwei Chen , Yucong Chen , Daniel Tianming Chen , Minjeong Cho , Min-Kook Choi , Chuantao Xie Chuantao Xie , Dana Cobzas , Julien Cohen-Adad , Jorge Corral Acero , Sujit Kumar Das , Marcela de Oliveira , Hanqiu Deng , Guiming Dong , Lars Doorenbos , Cory Efird , Sergio Escalera , Di Fan , Mehdi Fatan Serj , Alexandre Fenneteau , Lucas Fidon , Patryk Filipiak , René Finzel , Nuno R. Freitas , Christoph M. Friedrich , Mitchell Fulton , Finn Gaida , Francesco Galati , Christoforos Galazis , Chang Hee Gan , Zheyao Gao , Shengbo Gao , Matej Gazda , Beerend Gerats , Neil Getty , Adam Gibicar , Ryan Gifford , Sajan Gohil , Maria Grammatikopoulou , Daniel Grzech , Orhun Güley , Timo Günnemann , Chunxu Guo , Sylvain Guy , Heonjin Ha , Luyi Han , Il Song Han , Ali Hatamizadeh , Tian He , Jimin Heo , Sebastian Hitziger , SeulGi Hong , SeungBum Hong , Rian Huang , Ziyan Huang , Markus Huellebrand , Stephan Huschauer , Mustaffa Hussain , Tomoo Inubushi , Ece Isik Polat , Mojtaba Jafaritadi , SeongHun Jeong , Bailiang Jian , Yuanhong Jiang , Zhifan Jiang , Yueming Jin , Smriti Joshi , Abdolrahim Kadkhodamohammadi , Reda Abdellah Kamraoui , Inha Kang , Junghwa Kang , Davood Karimi , April Khademi , Muhammad Irfan Khan , Suleiman A. Khan , Rishab Khantwal , Kwang-Ju Kim , Timothy Kline , Satoshi Kondo , Elina Kontio , Adrian Krenzer , Artem Kroviakov , Hugo Kuijf , Satyadwyoom Kumar , Francesco La Rosa , Abhi Lad , Doohee Lee , Minho Lee , Chiara Lena , Hao Li , Ling Li , Xingyu Li , Fuyuan Liao , KuanLun Liao , Arlindo Limede Oliveira , Chaonan Lin , Shan Lin , Akis Linardos , Marius George Linguraru , Han Liu , Tao Liu , Di Liu , Yanling Liu , João Lourenço-Silva , Jingpei Lu , Jiangshan Lu , Imanol Luengo , Christina B. Lund , Huan Minh Luu , Yi Lv , Yi Lv , Uzay Macar , Leon Maechler , Sina Mansour L. , Kenji Marshall , Moona Mazher , Richard McKinley , Alfonso Medela , Felix Meissen , Mingyuan Meng , Dylan Miller , Seyed Hossein Mirjahanmardi , Arnab Mishra , Samir Mitha , Hassan Mohy-ud-Din , Tony Chi Wing Mok , Gowtham Krishnan Murugesan , Enamundram Naga Karthik , Sahil Nalawade , Jakub Nalepa , Mohamed Naser , Ramin Nateghi , Hammad Naveed , Quang-Minh Nguyen , Cuong Nguyen Quoc , Brennan Nichyporuk , Bruno Oliveira , David Owen , Jimut Bahan Pal , Junwen Pan , Wentao Pan , Winnie Pang , Bogyu Park , Vivek Pawar , Kamlesh Pawar , Michael Peven , Lena Philipp , Tomasz Pieciak , Szymon Plotka , Marcel Plutat , Fattaneh Pourakpour , Domen Preložnik , Kumaradevan Punithakumar , Abdul Qayyum , Sandro Queirós , Arman Rahmim , Salar Razavi , Jintao Ren , Mina Rezaei , Jonathan Adam Rico , ZunHyan Rieu , Markus Rink , Johannes Roth , Yusely Ruiz-Gonzalez , Numan Saeed , Anindo Saha , Mostafa Salem , Ricardo Sanchez-Matilla , Kurt Schilling , Wei Shao , Zhiqiang Shen , Ruize Shi , Pengcheng Shi , Daniel Sobotka , Théodore Soulier , Bella Specktor Fadida , Danail Stoyanov , Timothy Sum Hon Mun , Xiaowu Sun , Rong Tao , Franz Thaler , Antoine Théberge , Felix Thielke , Helena Torres , Kareem A. Wahid , Jiacheng Wang , YiFei Wang , Wei Wang , Xiong Wang , Jianhui Wen , Ning Wen , Marek Wodzinski , Ye Wu , Fangfang Xia , Tianqi Xiang , Chen Xiaofei , Lizhan Xu , Tingting Xue , Yuxuan Yang , Lin Yang , Kai Yao , Huifeng Yao , Amirsaeed Yazdani , Michael Yip , Hwanseung Yoo , Fereshteh Yousefirizi , Shunkai Yu , Lei Yu , Jonathan Zamora , Ramy Ashraf Zeineldin , Dewen Zeng , Jianpeng Zhang , Bokai Zhang , Jiapeng Zhang , Fan Zhang , Huahong Zhang , Zhongchen Zhao , Zixuan Zhao , Jiachen Zhao , Can Zhao , Qingshuo Zheng , Yuheng Zhi , Ziqi Zhou , Baosheng Zou , Klaus Maier-Hein , Paul F. Jäger , Annette Kopp-Schneider , Lena Maier-Hein

This paper investigates the critical problem of representation similarity evolution during cross-domain transfer learning, with particular focus on understanding why pre-trained models maintain effectiveness when adapted to medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Wenqiang Zu , Shenghao Xie , Hao Chen , Lei Ma