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Existing strategies for determining the optimal treatment or monitoring strategy typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or…

Applications · Statistics 2019-03-18 Ellen C Caniglia , Eleanor J Murray , Miguel A Hernan , Zach Shahn

Recent shifts in global health priorities have positioned Population Health Management (PHM) as a central area of focus. However, optimizing PHM strategies presents several challenges: managing high-dimensional patient covariates, tracking…

Optimization and Control · Mathematics 2026-04-10 Daniel Adelman , Alba V Olivares-Nadal , Miaolan Xie

Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not…

A model-based signal processing framework is proposed for pandemic trend forecasting and control, by using non-pharmaceutical interventions (NPI) at regional and country levels worldwide. The control objective is to prescribe quantifiable…

Optimization and Control · Mathematics 2021-11-23 Reza Sameni

Multi-task reinforcement learning aims to quickly identify solutions for new tasks with minimal or no additional interaction with the environment. Generalized Policy Improvement (GPI) addresses this by combining a set of base policies to…

Machine Learning · Computer Science 2025-11-14 Lucas N. Alegre , Ana L. C. Bazzan , André Barreto , Bruno C. da Silva

Many societal challenges, such as climate change or disease outbreaks, require coordinated behavioral changes. For many behaviors, the tendency of individuals to adhere to social norms can reinforce the status quo. However, these same…

This paper studies the problem of performing a sequence of optimal interventions in a causal dynamical system where both the target variable of interest and the inputs evolve over time. This problem arises in a variety of domains e.g.…

Machine Learning · Statistics 2021-10-27 Virginia Aglietti , Neil Dhir , Javier González , Theodoros Damoulas

In Influence Maximization (IM), the objective is to -- given a budget -- select the optimal set of entities in a network to target with a treatment so as to maximize the total effect. For instance, in marketing, the objective is to target…

Social and Information Networks · Computer Science 2025-06-05 Daan Caljon , Jente Van Belle , Jeroen Berrevoets , Wouter Verbeke

Coordination of distributed agents is required for problems arising in many areas, including multi-robot systems, networking and e-commerce. As a formal framework for such problems, we use the decentralized partially observable Markov…

Artificial Intelligence · Computer Science 2014-01-16 Daniel S. Bernstein , Christopher Amato , Eric A. Hansen , Shlomo Zilberstein

Safe policy improvement (SPI) is an offline reinforcement learning problem in which a new policy that reliably outperforms the behavior policy with high confidence needs to be computed using only a dataset and the behavior policy. Markov…

Artificial Intelligence · Computer Science 2025-08-20 Kasper Engelen , Guillermo A. Pérez , Marnix Suilen

In recommender systems, reinforcement learning solutions have shown promising results in optimizing the interaction sequence between users and the system over the long-term performance. For practical reasons, the policy's actions are…

Information Retrieval · Computer Science 2024-06-19 Xiaobei Wang , Shuchang Liu , Xueliang Wang , Qingpeng Cai , Lantao Hu , Han Li , Peng Jiang , Kun Gai , Guangming Xie

Predicting which action (treatment) will lead to a better outcome is a central task in decision support systems. To build a prediction model in real situations, learning from biased observational data is a critical issue due to the lack of…

Machine Learning · Statistics 2020-06-11 Akira Tanimoto , Tomoya Sakai , Takashi Takenouchi , Hisashi Kashima

Decision makers often want to target interventions so as to maximize an outcome that is observed only in the long-term. This typically requires delaying decisions until the outcome is observed or relying on simple short-term proxies for the…

Machine Learning · Computer Science 2022-04-12 Jeremy Yang , Dean Eckles , Paramveer Dhillon , Sinan Aral

In this article, we propose a novel pessimism-based Bayesian learning method for optimal dynamic treatment regimes in the offline setting. When the coverage condition does not hold, which is common for offline data, the existing solutions…

Machine Learning · Statistics 2023-02-23 Yunzhe Zhou , Zhengling Qi , Chengchun Shi , Lexin Li

The decoding of brain signals recorded via, e.g., an electroencephalogram, using machine learning is key to brain-computer interfaces (BCIs). Stimulation parameters or other experimental settings of the BCI protocol typically are chosen…

Neurons and Cognition · Quantitative Biology 2021-09-14 Jan Sosulski , David Hübner , Aaron Klein , Michael Tangermann

Decisions in public health are almost always made in the context of uncertainty. Policy makers are responsible for making important decisions, faced with the daunting task of choosing from amongst many possible options. This task is called…

Artificial Intelligence · Computer Science 2020-05-19 Atiye Alaeddini , Daniel Klein

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

Machine Learning · Computer Science 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

Machine Learning · Computer Science 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

Health-related data is noisy and stochastic in implying the true physiological states of patients, limiting information contained in single-moment observations for sequential clinical decision making. We model patient-clinician interactions…

Artificial Intelligence · Computer Science 2019-05-21 Luchen Li , Matthieu Komorowski , Aldo A. Faisal

Machine Learning systems are increasingly deployed in decision-making settings that shape user behavior and, in turn, the data on which future decisions are based. Performative Prediction (PP) formalizes this feedback loop by modeling how…

Machine Learning · Computer Science 2026-05-13 Javier Sanguino Bautiste , Thomas Kehrenberg , Jose A. Lozano , Novi Quadrianto