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We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Santiago Toledo-Cortés , Diego H. Useche , Fabio A. González

Self-supervised learning (SSL) has emerged as a key technique for training networks that can generalize well to diverse tasks without task-specific supervision. This property makes SSL desirable for computational pathology, the study of…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Eric Zimmermann , Neil Tenenholtz , James Hall , George Shaikovski , Michal Zelechowski , Adam Casson , Fausto Milletari , Julian Viret , Eugene Vorontsov , Siqi Liu , Kristen Severson

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Dwarikanath Mahapatra

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

Gleason grading from histopathology images is essential for accurate prostate cancer (PCa) diagnosis. Since such images are obtained after invasive tissue resection quick diagnosis is challenging under the existing paradigm. We propose a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Dwarikanath Mahapatra

Self-supervised learning (SSL) has become a popular method for generating invariant representations without the need for human annotations. Nonetheless, the desired invariant representation is achieved by utilising prior online…

Machine Learning · Computer Science 2024-09-30 Foivos Ntelemis , Yaochu Jin , Spencer A. Thomas

Self-Supervised Learning (SSL) presents an exciting opportunity to unlock the potential of vast, untapped clinical datasets, for various downstream applications that suffer from the scarcity of labeled data. While SSL has revolutionized…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Tassilo Wald , Constantin Ulrich , Stanislav Lukyanenko , Andrei Goncharov , Alberto Paderno , Maximilian Miller , Leander Maerkisch , Paul F. Jäger , Klaus Maier-Hein

For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage. However, Gleason scoring is based on subjective microscopic examination of tumor…

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Deep learning models for medical image classification usually achieve promising results but typically rely on large, annotated datasets or standard transfer learning from ImageNet. Self-Supervised Learning (SSL) has emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Joao Batista Florindo , Amanda Pontes de Oliveira Ornelas

Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Remy Peyret , Duaa alSaeed , Fouad Khelifi , Nadia Al-Ghreimil , Heyam Al-Baity , Ahmed Bouridane

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Digital pathological analysis is run as the main examination used for cancer diagnosis. Recently, deep learning-driven feature extraction from pathology images is able to detect genetic variations and tumor environment, but few studies…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Haojie Huang , Gongming Zhou , Xuejun Liu , Lei Deng , Chen Wu , Dachuan Zhang , Hui Liu

Histopathological image analysis is a reliable method for prostate cancer identification. In this paper, we present a comparative analysis of two approaches for segmenting glandular structures in prostate images to automate Gleason grading.…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Feda Bolus Al Baqain , Omar Sultan Al-Kadi

Pathologists diagnose and grade prostate cancer by examining tissue from needle biopsies on glass slides. The cancer's severity and risk of metastasis are determined by the Gleason grade, a score based on the organization and morphology of…

Image and Video Processing · Electrical Eng. & Systems 2022-09-28 Alessandro Ferrero , Beatrice Knudsen , Deepika Sirohi , Ross Whitaker

Prostate cancer is a dominant health concern calling for advanced diagnostic tools. Utilizing digital pathology and artificial intelligence, this study explores the potential of 11 deep neural network architectures for automated Gleason…

Self-supervised learning (SSL) methods have achieved remarkable success in learning image representations allowing invariances in them - but therefore discarding transformation information that some computer vision tasks actually require.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Qin Wang , Alessio Quercia , Benjamin Bruns , Abigail Morrison , Hanno Scharr , Kai Krajsek

Despite its practical importance across a wide range of modalities, recent advances in self-supervised learning (SSL) have been primarily focused on a few well-curated domains, e.g., vision and language, often relying on their…

Machine Learning · Computer Science 2023-10-26 Huiwon Jang , Jihoon Tack , Daewon Choi , Jongheon Jeong , Jinwoo Shin

Cervical cancer is the second most prevalent cancer affecting women today. As the early detection of cervical carcinoma relies heavily upon screening and pre-clinical testing, digital cervicography has great potential as a primary or…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Yanglan Ou , Yuan Xue , Ye Yuan , Tao Xu , Vincent Pisztora , Jia Li , Xiaolei Huang