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In image denoising problems, one widely-adopted approach is to minimize a regularized data-fit objective function, where the data-fit term is derived from a physical image acquisition model. Typically the regularizer is selected with two…
In the study of condensed matter physics, spectral information plays an important role for understand the mechanism of materials. However, it is difficult to obtain the spectrum directly through experiments or simulation. For example, the…
Fluorescence molecular tomography (FMT) is an emerging powerful tool for biomedical research. There are two factors that influence FMT reconstruction most effectively. The first one is the regularization techniques. Traditional methods such…
A fruitful approach for solving signal deconvolution problems consists of resorting to a frame-based convex variational formulation. In this context, parallel proximal algorithms and related alternating direction methods of multipliers have…
In this work, we present denoiSplit, a method to tackle a new analysis task, i.e. the challenge of joint semantic image splitting and unsupervised denoising. This dual approach has important applications in fluorescence microscopy, where…
We propose an image deconvolution algorithm when the data is contaminated by Poisson noise. The image to restore is assumed to be sparsely represented in a dictionary of waveforms such as the wavelet or curvelet transforms. Our key…
Image blur and image noise are imaging artifacts intrinsically arising in image acquisition. In this paper, we consider multi-frame blind deconvolution (MFBD), where image blur is described by the convolution of an unobservable,…
We propose an unfolded accelerated projected-gradient descent procedure to estimate model and algorithmic parameters for image super-resolution and molecule localization problems in image microscopy. The variational lower-level constraint…
In multi-view fluorescence microscopy, each angular acquisition needs to be aligned with care to obtain an optimal volumetric reconstruction. Here, instead, we propose a neat protocol based on auto-correlation inversion, that leads directly…
This paper presents a novel method for restoring digital videos via a Deep Plug-and-Play (PnP) approach. Under a Bayesian formalism, the method consists in using a deep convolutional denoising network in place of the proximal operator of…
In this paper, we study the problem of recovering a sharp version of a given blurry image when the blur kernel is unknown. Previous methods often introduce an image-independent regularizer (such as Gaussian or sparse priors) on the desired…
The use of denoisers for image reconstruction has shown significant potential, especially for the Plug-and-Play (PnP) framework. In PnP, a powerful denoiser is used as an implicit regularizer in proximal algorithms such as ISTA and ADMM.…
Plug-and-play (PnP) method is a recent paradigm for image regularization, where the proximal operator (associated with some given regularizer) in an iterative algorithm is replaced with a powerful denoiser. Algorithmically, this involves…
In recent years, large convolutional neural networks have been widely used as tools for image deblurring, because of their ability in restoring images very precisely. It is well known that image deblurring is mathematically modeled as an…
Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…
Removing the aberrations introduced by the Point Spread Function (PSF) is a fundamental aspect of astronomical image processing. The presence of noise in observed images makes deconvolution a nontrivial task that necessitates the use of…
Low-light, long-exposure defocus deblurring remains a challenging problem due to the simultaneous presence of severe blur and complex biased noise. Existing methods typically rely on simplified noise assumptions, which limits their…
Single particle reconstruction has recently emerged in 3D fluorescence microscopy as a powerful technique to improve the axial resolution and the degree of fluorescent labeling. It is based on the reconstruction of an average volume of a…
Due to the fast inference and good performance, discriminative learning methods have been widely studied in image denoising. However, these methods mostly learn a specific model for each noise level, and require multiple models for…
We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…