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Longitudinal item response data are common in social science, educational science, and psychology, among other disciplines. Studying the time-varying relationships between items is crucial for educational assessment or designing marketing…
Segmentation of blood vessels in retinal images provides early diagnosis of diseases like glaucoma, diabetic retinopathy and macular degeneration. Among these diseases occurrence of Glaucoma is most frequent and has serious ocular…
The analysis of population-wide datasets can provide insight on the health status of large populations so that public health officials can make data-driven decisions. The analysis of such datasets often requires highly parameterized models…
As a representative optic degenerative condition, glaucoma has been a threat to millions due to its irreversibility and severe impact on human vision fields. Mainly characterized by dimmed and blurred visions, or peripheral vision loss,…
We evaluated whether a glaucoma risk assessment (GRA) model trained on All of Us national data can identify patients at high probability of glaucoma using only systemic electronic health records (EHR) at an independent institution. In this…
Longitudinal processes are often associated with each other over time; therefore, it is important to investigate the associations among developmental processes and understand their joint development. The latent growth curve model (LGCM)…
The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…
We present a novel approach for the analysis of multivariate case-control georeferenced data using Bayesian inference in the context of disease mapping, where the spatial distribution of different types of cancers is analyzed. Extending…
Understanding individual differences in cortical structure is key to advancing diagnostics in neurology and psychiatry. Reference models aid in detecting aberrant cortical thickness, yet site-specific biases limit their direct application…
Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…
High-dimensional vector autoregressive (VAR) models offer a versatile framework for multivariate time series analysis, yet face critical challenges from over-parameterization and uncertain lag order. In this paper, we systematically compare…
Analyzing temporal developments is crucial for the accurate prognosis of many medical conditions. Temporal changes that occur over short time scales are key to assessing the health of physiological functions, such as the cardiac cycle.…
The integration of longitudinal measurements and survival time in statistical modeling offers a powerful framework for capturing the interplay between these two essential outcomes, particularly when they exhibit associations. However, in…
Taking into account that glaucoma is the leading cause of blindness worldwide, we propose in this paper three different learning methodologies for glaucoma detection in order to elucidate that traditional machine-learning techniques could…
In real-world scene perception human observers generate sequences of fixations to move image patches into the high-acuity center of the visual field. Models of visual attention developed over the last 25 years aim to predict two-dimensional…
Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…
Imaging genetics aims to uncover the hidden relationship between imaging quantitative traits (QTs) and genetic markers (e.g. single nucleotide polymorphism (SNP)), and brings valuable insights into the pathogenesis of complex diseases, such…
Road traffic casualties represent a hidden global epidemic, demanding evidence-based interventions. This paper demonstrates a network lattice approach for identifying road segments of particular concern, based on a case study of a major…
Dermatologists often diagnose or rule out early melanoma by evaluating the follow-up dermoscopic images of skin lesions. However, existing algorithms for early melanoma diagnosis are developed using single time-point images of lesions.…
Spatial regression is widely used for modeling the relationship between a dependent variable and explanatory covariates. Oftentimes, the linear relationships vary across space, when some covariates have location-specific effects on the…