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Transient electric fields across cell bilayer membranes can lead to electroporation, as well as to cell fusion, and have been extensively studied. We find that transmembrane electric fields similar to those in cells can lead to a massive,…

Materials Science · Physics 2023-06-27 Yu Zhang , Di Jin , Ran Tivony , Nir Kampf , Jacob Klein

It was recently discovered that friction between surfaces bearing phosphatidylcholine (PC) lipid bilayers can be increased by two orders of magnitude or more via an externally-applied electric field, and that this increase is fully…

Soft Condensed Matter · Physics 2024-09-26 Di Jin , Jacob Klein

Contrary to existing theoretical models, experimental evidence points out that electroporation (membrane defect formation under external electric fields) starts to occur within the range of transmembrane voltages that cells may routinely…

Biological Physics · Physics 2007-05-23 Zlatko Vasilkoski

The electropermeabilization of biological cell membranes by the application of an external field occurs whenever an applied field exceeds a threshold value. For fields above this threshold value but less than another critical value, the…

Biological Physics · Physics 2007-05-23 William A. Hercules , James Lindesay , Anna Coble , Robert Schmukler

For many biotechnological applications it would be useful to better understand the effects produced by electric fields on lipid membranes. This review discusses several aspects of the electrostatic properties of a planar lipid membrane with…

Soft Condensed Matter · Physics 2014-11-25 Falko Ziebert , David Lacoste

The influence of an electric field on a poorly conductive membrane such as a lipid bilayer is studied theoretically. The unbalanced electric stress created by an ionic current across a non-perfectly flat membrane gives rise to a…

Soft Condensed Matter · Physics 2009-11-07 Pierre Sens , Hervé Isambert

Bilayer lipid membranes [BLMs] are an essential component of all biological systems, forming a functional barrier for cells and organelles from the surrounding environment. The lipid molecules that form membranes contain both permanent and…

Biological Physics · Physics 2015-03-17 Richard J. Bingham , Peter D. Olmsted , Stephen W. Smye

Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions.…

Analysis of PDEs · Mathematics 2013-09-24 Michael Mikucki , Y. C. Zhou

Electrochemical phenomena in biology often unfold in confined geometries where micrometer- to millimeter-scale domains coexist with nanometer-scale interfacial diffuse charge layers. We analyze a model lipid membrane-electrolyte system…

Soft Condensed Matter · Physics 2025-08-20 Joshua B. Fernandes , Hyeongjoo Row , Kranthi K. Mandadapu , Karthik Shekhar

The effect of AC electric fields on the elasticity of supported lipid bilayers has been investigated at the microscopic level using grazing incidence synchrotron x-ray scattering. A strong decrease in the membrane tension up to 1mN/m and a…

Soft Condensed Matter · Physics 2016-06-08 Arnaud Hemmerle , Thierry Charitat , Giovanna Fragneto , Jean Daillant

Fusion of lipid bilayers in membranes is important in processes from vesicle-cell interactions (as in drug delivery) to exosome-cell signaling, while transient transmembrane electric fields are known to occur spontaneously. Two contacting…

Soft Condensed Matter · Physics 2024-04-09 Yu Zhang , Di Jin , Jacob Klein

This paper presents a model and numerical analysis (simulations) of transmembrane potential induced in biological cell membrane under the influence of externally applied electric field (i.e., electroporation). This model differs from the…

Biological Physics · Physics 2009-11-13 Pratip Shil , Salil Bidaye , Pandit B. Vidyasagar

The electric field of biological membranes has long been treated as a one-dimensional quantity, defined solely by the component normal to the bilayer (E_VERT). Here, we present a bioelectronic platform that enables controlled generation of…

We theoretically explore the effect of a transverse electric field on the frictional response of a bi-layer of packed zwitterionic molecules. The dipole-moment reorientation promoted by the electric field can lead to either stick-slip or…

Soft Condensed Matter · Physics 2024-04-16 Melisa M. Gianetti , Roberto Guerra , Andrea Vanossi , Michael Urbakh , Nicola Manini

The behavior of lipid membranes in the presence of an external electric field is studied and used to examine the influence of such fields on membrane parameters such as roughness and show that for a micro sized membrane, roughness grows as…

Soft Condensed Matter · Physics 2007-11-12 M Neek-Amal , H. Rafii-Tabar , H. R. Sepangi

Electroporation of biological cell membranes is a phenomena that occurs almost universally at a transmembrane potential of approximately 1000 mV. Theories of pore formation have been proposed based on electrocompression (Crowley 1972,…

Biological Physics · Physics 2007-05-23 William A Hercules , James Lindesay , Anna Coble

Biomembranes are thin capacitors with the unique feature of displaying phase transitions in a physiologically relevant regime. We investigate the voltage and lateral pressure dependence of their capacitance close to their chain melting…

Biological Physics · Physics 2012-09-18 Thomas Heimburg

An external electric field changes the physical properties of polar-liquids due to the reorientation of their permanent dipoles. For example it should affect significantly the physical properties of water confined in a nanochannel. The…

Mesoscale and Nanoscale Physics · Physics 2016-08-03 Sobrino Fernández Mario , M. Neek-Amal , F. M. Peeters

Experiments on supported lipid bilayers featuring liquid ordered/disordered domains have shown that the spatial arrangement of the lipid domains and their chemical composition are strongly affected by the curvature of the substrate.…

Soft Condensed Matter · Physics 2021-02-17 Melissa Rinaldin , Piermarco Fonda , Luca Giomi , Daniela J. Kraft

Since a long time the application of small electric potentials on biological membranes (iontophoresis) proved enabling control and improvement of transdermal delivery of substances across this barrier. In spite of a large experimental data,…

Tissues and Organs · Quantitative Biology 2019-05-07 Neila Machado , Clarissa Callegaro , Marcelo Augusto Christoffolete , Herculano Martinho
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