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The identification, and subsequent discovery, of fast radio transients through blind-search surveys requires a large amount of processing power, in worst cases scaling as $\mathcal{O}(N^3)$. For this reason, survey data are generally…

Instrumentation and Methods for Astrophysics · Physics 2014-02-04 Alessio Magro , Aris Karastergiou , Stefano Salvini , Benjamin Mort , Fred Dulwich , Kristian Zarb Adami

Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical…

Medical Physics · Physics 2015-05-14 Xuejun Gu , Dongju Choi , Chunhua Men , Hubert Pan , Amitava Majumdar , Steve B. Jiang

Cancer is the second leading cause of death, with chemotherapy as one of the primary forms of treatment. As a result, researchers are turning to drug combination therapy to decrease drug resistance and increase efficacy. Current methods of…

Quantitative Methods · Quantitative Biology 2024-11-08 Zachary Schwehr

The emergence of digital pathology has opened new horizons for histopathology and cytology. Artificial-intelligence algorithms are able to operate on digitized slides to assist pathologists with diagnostic tasks. Whereas machine learning…

Background: Gliomas are the most common brain tumors, which vary from low to high-grade. Despite the improvements in imaging techniques in the last decade, all parts of the tumor are not visible in these images, due to having a threshold of…

Other Quantitative Biology · Quantitative Biology 2023-09-06 Farshad Samadifam , Ehsan Ghafourian

Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…

In surgical oncology, it is challenging for surgeons to identify lymph nodes and completely resect cancer even with pre-operative imaging systems like PET and CT, because of the lack of reliable intraoperative visualization tools.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Baoru Huang , Yicheng Hu , Anh Nguyen , Stamatia Giannarou , Daniel S. Elson

Purpose: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape. Methods: Data from 322 GK treatment plans…

Medical Physics · Physics 2023-01-09 Binghao Zhang , Aaron Babier , Timothy C. Y. Chan , Mark Ruschin

In this paper, we present a GPU-accelerated prototype implementation of a portable ultrasound imaging pipeline on an Nvidia CLARA AGX development kit. The raw data is acquired with nonsteered plane wave transmit using a programmable…

Medical Physics · Physics 2024-10-03 V. Arun Kumar , A. N. Madhavanunni , Mahesh Raveendranatha Panicker

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

We present a nonparametric Bayesian method for disease subtype discovery in multi-dimensional cancer data. Our method can simultaneously analyse a wide range of data types, allowing for both agreement and disagreement between their…

Genomics · Quantitative Biology 2013-04-16 Richard S. Savage , Zoubin Ghahramani , Jim E. Griffin , Paul Kirk , David L. Wild

Accurate delineation of the intraprostatic gross tumour volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen positron emission tomography (PSMA-PET) may…

Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…

The exposure sequence is being actively studied for user interest modeling in Click-Through Rate (CTR) prediction. However, the existing methods for exposure sequence modeling bring extensive computational burden and neglect noise problems,…

Information Retrieval · Computer Science 2022-05-02 Xiaoxiao Xu , Zhiwei Fang , Qian Yu , Ruoran Huang , \\Chaosheng Fan , Yong Li , Yang He , Changping Peng , Zhangang Lin , Jingping Shao

We present a fast and reliable algorithm that gives precise location of breast tumours for a partial mastectomy. Our algorithm is fully implemented in the Surface Evolver, which is a general-purpose simulator of physical experiments. By…

Image and Video Processing · Electrical Eng. & Systems 2019-12-02 Marcelo Zanchetta do Nascimento , Valério Ramos Batista

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

We describe a visual computing approach to radiation therapy (RT) planning, based on spatial similarity within a patient cohort. In radiotherapy for head and neck cancer treatment, dosage to organs at risk surrounding a tumor is a large…

Medical Physics · Physics 2019-10-14 A. Wentzel , P. Hanula , T. Luciani , B. Elgohari , H. Elhalawani , G. Canahuate , D. Vock , C. D. Fuller , G. E. Marai

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

Machine Learning · Statistics 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Radiation therapy (RT) is a medical treatment to kill cancer cells or shrink tumors. To manually schedule patients for RT is a time-consuming and challenging task. By the use of optimization, patient schedules for RT can be created…

Optimization and Control · Mathematics 2023-05-04 Sara Frimodig , Per Enqvist , Mats Carlsson , Carole Mercier

BACKGROUND: Targeted Radionuclide Therapy (TRT) is a fast-growing field garnering much interest, however, dosimetry calculation techniques remain relatively simple. PURPOSE: To introduce egs_mird, a new Monte Carlo application built in…

Medical Physics · Physics 2022-04-06 Martin P. Martinov , Chidera Opera , Rowan M. Thomson , Ting-Yim Lee