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The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…

Physics and Society · Physics 2021-07-26 Hugo Dolan , Riccardo Rastelli

We consider the low-prevalence linearized SEIR epidemic model for a society that has resolved to keep future infections low in anticipation of a vaccine. The society can vary its amount of potentially-infection-spreading activity over time,…

Optimization and Control · Mathematics 2020-09-17 Scott Sheffield

Fairness in vaccination is not only important from a social justice point of view, but experience has shown that a fair distribution of vaccine proves more effective in public immunization by preventing highly-concentrated infected areas to…

Optimization and Control · Mathematics 2021-11-11 Mohammad Firouz , Linda Li , Daizy Ahmed , Abdulaziz Ahmed

The paper considers the problems of optimal vaccination control in the classical SIR model under constraints on the resource capabilities of the insurance medical system, in particular under constraints on the possible absolute rate of…

Optimization and Control · Mathematics 2025-11-24 Bogdan Norkin , Vladimir Norkin

We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…

Populations and Evolution · Quantitative Biology 2022-06-28 Omar El Deeb , Maya Jalloul

Most governments employ a set of quasi-standard measures to fight COVID-19 including wearing masks, social distancing, virus testing, contact tracing, and vaccination. However, combining these measures into an efficient holistic pandemic…

Theoretical Economics · Economics 2022-02-10 Balázs Pejó , Gergely Biczók

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Given the severe impact of COVID-19 on several societal levels, it is of crucial importance to model the impact of restriction measures on the pandemic evolution, so that governments are able to take informed decisions. Even though there…

Computers and Society · Computer Science 2022-02-03 Greta Malaspina , Stevo Racković , Filipa Valdeira

We consider the problem of optimizing locations of distribution centers (DCs) and plans for distributing resources such as test kits and vaccines, under spatiotemporal uncertainties of disease spread and demand for the resources. We aim to…

Optimization and Control · Mathematics 2022-07-19 Beste Basciftci , Xian Yu , Siqian Shen

The limited availability of COVID-19 vaccines has prompted extensive research on optimal vaccination strategies. Previous studies have considered various non-pharmaceutical interventions, vaccine efficacy, and distribution strategies. In…

Populations and Evolution · Quantitative Biology 2025-02-27 Iker Atienza-Diez , Gabriel Rodriguez-Maroto , Saúl Ares , Susanna Manrubia

This study develops an economic model for a social planner who prioritizes health over short-term wealth accumulation during a pandemic. Agents are connected through a weighted undirected network of contacts, and the planner's objective is…

Theoretical Economics · Economics 2021-10-22 Roland Pongou , Guy Tchuente , Jean-Baptiste Tondji

The success of a vaccination program is crucially dependent on its adoption by a critical fraction of the population, as the resulting herd immunity prevents future outbreaks of an epidemic. However, the effectiveness of a campaign can…

Physics and Society · Physics 2019-07-02 Anupama Sharma , Shakti N. Menon , V. Sasidevan , Sitabhra Sinha

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

Populations and Evolution · Quantitative Biology 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…

Dynamical Systems · Mathematics 2023-02-01 Shoshana Elgart

Since the end of 2019, COVID-19 has significantly affected the lives of people around the world. Towards the end of 2020, several COVID-19 vaccine candidates with relatively high efficacy have been reported in the final phase of clinical…

Physics and Society · Physics 2021-01-20 W. K. Wong , Filbert H. Juwono , Tock H. Chua

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…

Dynamical Systems · Mathematics 2024-08-16 Yi Jiang , Kristin M. Kurianski , Jane HyoJin Lee , Yanping Ma , Daniel Cicala , Glenn Ledder

The initial period of vaccination shows strong heterogeneity between countries' vaccinations rollout, both in the terms of the start of the vaccination process and in the dynamics of the number of people that are vaccinated. A predominant…

General Economics · Economics 2021-03-09 Dragan Tevdovski , Petar Jolakoski , Viktor Stojkoski

It has been one year since the outbreak of the COVID-19 pandemic. The good news is that vaccines developed by several manufacturers are being actively distributed worldwide. However, as more and more vaccines become available to the public,…

Social and Information Networks · Computer Science 2021-07-07 Wei Wu , Hanjia Lyu , Jiebo Luo