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Objective: Many recent studies have suggested that brain deformation resulting from a head impact is linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI). Even though several finite element (FE) head…

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Timely implementation of interventions to slow cognitive decline among older adults requires accurate monitoring to detect changes in cognitive function. Data gathered using wearable devices that can continuously monitor factors known to be…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Collin Sakal , Tingyou Li , Juan Li , Xinyue Li

Determining whether hypotensive patients in intensive care units (ICUs) should receive fluid bolus therapy (FBT) has been an extremely challenging task for intensive care physicians as the corresponding increase in blood pressure has been…

Machine Learning · Computer Science 2018-12-04 Uma M. Girkar , Ryo Uchimido , Li-wei H. Lehman , Peter Szolovits , Leo Celi , Wei-Hung Weng

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

The global pandemic caused by COVID-19 affects our lives in all aspects. As of September 11, more than 28 million people have tested positive for COVID-19 infection, and more than 911,000 people have lost their lives in this virus battle.…

Machine Learning · Computer Science 2021-11-29 Yuqi Meng , Qiancheng Sun , Suning Hong , Ying Zhao , Zhixiang Li

Existing methods to characterise the evolving condition of traumatic brain injury (TBI) patients in the intensive care unit (ICU) do not capture the context necessary for individualising treatment. Here, we integrate all heterogenous data…

Background: Most acute stroke (AS) patients in the United States are initially evaluated at a primary stroke center (PSC) and a significant proportion requires transfer to a comprehensive stroke center (CSC) for advanced treatment. A CSC…

Quantitative Methods · Quantitative Biology 2022-02-16 Hojun Choi , Ohad Perry , Jane Holl , Shyam Prabhakaran

Purpose: Multi-expert deep learning training methods to automatically quantify ischemic brain tissue on Non-Contrast CT Materials and Methods: The data set consisted of 260 Non-Contrast CTs from 233 patients of acute ischemic stroke…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Sophie Ostmeier , Brian Axelrod , Benjamin Pulli , Benjamin F. J. Verhaaren , Abdelkader Mahammedi , Yongkai Liu , Christian Federau , Greg Zaharchuk , Jeremy J. Heit

Clinician burnout poses a substantial threat to patient safety, particularly in high-acuity intensive care units (ICUs). Existing research predominantly relies on retrospective survey tools or broad electronic health record (EHR) metadata,…

Computation and Language · Computer Science 2025-09-08 Syed Ahmad Chan Bukhari , Fazel Keshtkar , Alyssa Meczkowska

Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention…

Signal Processing · Electrical Eng. & Systems 2020-12-03 Matthias Hüser , Adrian Kündig , Walter Karlen , Valeria De Luca , Martin Jaggi

Pain is a common occurrence among patients admitted to Intensive Care Units. Pain assessment in ICU patients still remains a challenge for clinicians and ICU staff, specifically in cases of non-verbal sedated, mechanically ventilated, and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Subhash Nerella , Kia Khezeli , Andrea Davidson , Patrick Tighe , Azra Bihorac , Parisa Rashidi

Background: The accurate prediction of postoperative complication risk using Electronic Health Records (EHR) and artificial intelligence shows great potential. Training a robust artificial intelligence model typically requires large-scale…

Dementia is a collection of symptoms associated with impaired cognition and impedes everyday normal functioning. Dementia, with Alzheimer's disease constituting its most common type, is highly complex in terms of etiology and…

This study proposes a deep learning model that effectively suppresses the false alarms in the intensive care units (ICUs) without ignoring the true alarms using single- and multimodal biosignals. Most of the current work in the literature…

Quantitative Methods · Quantitative Biology 2020-07-01 Sajad Mousavi , Atiyeh Fotoohinasab , Fatemeh Afghah

Clinical practice in psychiatry is burdened with the increased demand for healthcare services and the scarce resources available. New paradigms of health data powered with machine learning techniques could open the possibility to improve…

Artificial Intelligence · Computer Science 2023-06-08 Juan Sebastian Canas , Francisco Gomez , Omar Costilla-Reyes

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare…

Quantitative Methods · Quantitative Biology 2019-09-19 Casey C. Bennett
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