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Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Delirium is an acute decline or fluctuation in attention, awareness, or other cognitive function that can lead to serious adverse outcomes. Despite the severe outcomes, delirium is frequently unrecognized and uncoded in patients' electronic…

A crucial step within secondary analysis of electronic health records (EHRs) is to identify the patient cohort under investigation. While EHRs contain medical billing codes that aim to represent the conditions and treatments patients may…

Patient monitoring is vital in all stages of care. We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an…

Machine Learning · Computer Science 2021-05-11 Khalid Alghatani , Nariman Ammar , Abdelmounaam Rezgui , Arash Shaban-Nejad

Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…

Machine Learning · Computer Science 2021-08-04 Maryam Pishgar , Martha Razo , Julian Theis , Houshang Darabi

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

Machine Learning · Computer Science 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background: Circadian desynchrony characterized by the misalignment between an individual's internal biological rhythms and external environmental cues, significantly affects various physiological processes and health outcomes. Quantifying…

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

Background: Patients with both diabetes mellitus (DM) and atrial fibrillation (AF) face elevated mortality in intensive care units (ICUs), yet models targeting this high-risk group remain limited. Objective: To develop an interpretable…

Machine Learning · Computer Science 2025-06-23 Li Sun , Shuheng Chen , Yong Si , Junyi Fan , Maryam Pishgar , Elham Pishgar , Kamiar Alaei , Greg Placencia

Background: Acute kidney injury (AKI) is a common complication in hospitalized patients and a common cause for chronic kidney disease (CKD) and increased hospital cost and mortality. By timely detection of AKI and AKI progression, effective…

Over the past decade the rate of care unit (CU) use in the United States has been increasing. With an aging population and ever-growing demand for medical care, effective management of patients' transitions among different care facilities…

Machine Learning · Computer Science 2016-11-11 Hongteng Xu , Weichang Wu , Shamim Nemati , Hongyuan Zha

Sepsis accounts for more than 50% of hospital deaths, and the associated cost ranks the highest among hospital admissions in the US. Improved understanding of disease states, severity, and clinical markers has the potential to significantly…

Quantitative Methods · Quantitative Biology 2022-10-11 Chih-Hao Fang , Vikram Ravindra , Salma Akhter , Mohammad Adibuzzaman , Paul Griffin , Shankar Subramaniam , Ananth Grama

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

Machine Learning · Computer Science 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

Predicting the risk of mortality for patients with acute myocardial infarction (AMI) using electronic health records (EHRs) data can help identify risky patients who might need more tailored care. In our previous work, we built…

Machine Learning · Computer Science 2019-04-30 Seyedeh Neelufar Payrovnaziri , Laura A. Barrett , Daniel Bis , Jiang Bian , Zhe He

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

Phenotyping is the process of distinguishing groups of patients to identify different types of disease progression. A recent trend employs low-rank matrix and tensor factorization methods for their capability of dealing with multi-modal,…

Machine Learning · Computer Science 2025-06-26 Cristian Minoccheri , Sophia Tesic , Kayvan Najarian , Ryan Stidham

Understanding the temporal dynamics of COVID-19 patient phenotypes is necessary to derive fine-grained resolution of pathophysiology. Here we use state-of-the-art deep neural networks over an institution-wide machine intelligence platform…

This study introduces an AI-driven platform for continuous and passive patient monitoring in hospital settings, developed by LookDeep Health. Leveraging advanced computer vision, the platform provides real-time insights into patient…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Paolo Gabriel , Peter Rehani , Tyler Troy , Tiffany Wyatt , Michael Choma , Narinder Singh

The intensive care unit (ICU) is a specialized hospital space where critically ill patients receive intensive care and monitoring. Comprehensive monitoring is imperative in assessing patients conditions, in particular acuity, and ultimately…

Artificial Intelligence · Computer Science 2024-11-25 Subhash Nerella , Ziyuan Guan , Scott Siegel , Jiaqing Zhang , Ruilin Zhu , Kia Khezeli , Azra Bihorac , Parisa Rashidi