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Purpose: Artificial intelligence (AI) solutions for medical diagnosis require thorough evaluation to demonstrate that performance is maintained for all patient sub-groups and to ensure that proposed improvements in care will be delivered…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Tom Dyer , Jordan Smith , Gaetan Dissez , Nicole Tay , Qaiser Malik , Tom Naunton Morgan , Paul Williams , Liliana Garcia-Mondragon , George Pearse , Simon Rasalingham

In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Renao Yan , Qiehe Sun , Cheng Jin , Yiqing Liu , Yonghong He , Tian Guan , Hao Chen

The integration of AI into radiology introduces opportunities for improved clinical care provision and efficiency but it demands a meticulous approach to mitigate potential risks as with any other new technology. Beginning with rigorous…

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Computational cytology faces two major challenges: i) instance-level labels are unreliable and prohibitively costly to obtain, ii) witness rates are extremely low. We propose SLAM-AGS, a Slide-Label-Aware Multitask pretraining framework…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Marco Acerbis , Swarnadip Chatterjee , Christophe Avenel , Joakim Lindblad

Prostate cancer represents a major threat to health. Early detection is vital in reducing the mortality rate among prostate cancer patients. One approach involves using multi-modality (CT, MRI, US, etc.) computer-aided diagnosis (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Rui Jin , Derun Li , Dehui Xiang , Lei Zhang , Hailing Zhou , Fei Shi , Weifang Zhu , Jing Cai , Tao Peng , Xinjian Chen

The surge in developing deep learning models for diagnosing skin lesions through image analysis is notable, yet their clinical black faces challenges. Current dermatology AI models have limitations: limited number of possible diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Deval Mehta , Brigid Betz-Stablein , Toan D Nguyen , Yaniv Gal , Adrian Bowling , Martin Haskett , Maithili Sashindranath , Paul Bonnington , Victoria Mar , H Peter Soyer , Zongyuan Ge

Cancer grading is an essential task in pathology. The recent developments of artificial neural networks in computational pathology have shown that these methods hold great potential for improving the accuracy and quality of cancer…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Jaeung Lee , Keunho Byeon , Jin Tae Kwak

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

This work shows promising results using multiple instance learning on salivary gland tumours in classifying cancers on whole slide images. Utilising CTransPath as a patch-level feature extractor and CLAM as a feature aggregator, an F1 score…

Image and Video Processing · Electrical Eng. & Systems 2024-08-23 John Charlton , Ibrahim Alsanie , Syed Ali Khurram

The discussions around Artificial Intelligence (AI) and medical imaging are centered around the success of deep learning algorithms. As new algorithms enter the market, it is important for practicing radiologists to understand the pitfalls…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Rishi Gadepally , Andrew Gomella , Eric Gingold , Paras Lakhani

Medical imaging plays a pivotal role in diagnosis and treatment in clinical practice. Inspired by the significant progress in automatic image captioning, various deep learning (DL)-based methods have been proposed to generate radiology…

Computer Vision and Pattern Recognition · Computer Science 2022-02-04 Yixin Wang , Zihao Lin , Zhe Xu , Haoyu Dong , Jiang Tian , Jie Luo , Zhongchao Shi , Yang Zhang , Jianping Fan , Zhiqiang He

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Artificial intelligence (AI) is being deployed within radiology at a rapid pace. AI has proven an excellent tool for reconstructing and enhancing images that appear sharper, smoother, and more detailed, can be acquired more quickly, and…

Artificial Intelligence · Computer Science 2026-02-11 Jana G. Delfino , Jason L. Granstedt , Frank W. Samuelson , Robert Ochs , Krishna Juluru

Radiology, being one of the younger disciplines of medicine with a history of just over a century, has witnessed tremendous technological advancements and has revolutionized the way we practice medicine today. In the last few decades,…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Suraj Ghuwalewala , Viraj Kulkarni , Richa Pant , Amit Kharat

Artificial intelligence has found increasing use for ovarian cancer morphological subtyping from histopathology slides, but the optimal magnification for computational interpretation is unclear. Higher magnifications offer abundant…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Jack Breen , Katie Allen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Artificial intelligence represents a new frontier in human medicine that could save more lives and reduce the costs, thereby increasing accessibility. As a consequence, the rate of advancement of AI in cancer medical imaging and more…

Human-in-the-loop validation is essential in safety-critical clinical AI, yet the transition between initial model inference and expert correction is rarely analyzed as a structured signal. We introduce a diagnostic alignment framework in…

Artificial Intelligence · Computer Science 2026-02-27 Dimitrios P. Panagoulias , Evangelia-Aikaterini Tsichrintzi , Georgios Savvidis , Evridiki Tsoureli-Nikita