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The overexpression of human epidermal growth factor receptor 2 (HER2) has been established as a therapeutic target in multiple types of cancers, such as breast and gastric cancers. Immunohistochemistry (IHC) is employed as a basic HER2 test…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Jun Zhang , Kuan Tian , Pei Dong , Haocheng Shen , Kezhou Yan , Jianhua Yao , Junzhou Huang , Xiao Han

Semi-supervised medical image segmentation aims to leverage minimal expert annotations, yet remains confronted by challenges in maintaining high-quality consistency learning. Excessive perturbations can degrade alignment and hinder precise…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Wenbo Xiao , Zhihao Xu , Guiping Liang , Yangjun Deng , Yi Xiao

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Understanding the trustworthiness of a prediction yielded by a classifier is critical for the safe and effective use of AI models. Prior efforts have been proven to be reliable on small-scale datasets. In this work, we study the problem of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Yan Luo , Yongkang Wong , Mohan S. Kankanhalli , Qi Zhao

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

The integration of artificial intelligence (AI), particularly Convolutional Neural Networks (CNNs), into dermatological diagnosis demonstrates substantial clinical potential. While existing literature predominantly benchmarks algorithmic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Loris Cino , Pier Luigi Mazzeo , Alessandro Martella , Giulia Radi , Renato Rossi , Cosimo Distante

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Detecting cancer manually in whole slide images requires significant time and effort on the laborious process. Recent advances in whole slide image analysis have stimulated the growth and development of machine learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Sanghoon Lee , Colton Farley , Simon Shim , Yanjun Zhao , Wookjin Choi , Wook-Sung Yoo

Accurate annotation of fixation type is a critical step in slide preparation for pathology laboratories. However, this manual process is prone to errors, impacting downstream analyses and diagnostic accuracy. Existing methods for verifying…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Oskar Thaeter , Tanja Niedermair , Jan E. G. Albin , Johannes Raffler , Ralf Huss , Peter J. Schüffler

Recently, self-supervised instance discrimination methods have achieved significant success in learning visual representations from unlabeled photographic images. However, given the marked differences between photographic and medical…

Image and Video Processing · Electrical Eng. & Systems 2022-04-18 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Michael B. Gotway , Jianming Liang

Detecting and classifying lesions in breast ultrasound images is a promising application of artificial intelligence (AI) for reducing the burden of cancer in regions with limited access to mammography. Such AI systems are more likely to be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Arianna Bunnell , Yannik Glaser , Dustin Valdez , Thomas Wolfgruber , Aleen Altamirano , Carol Zamora González , Brenda Y. Hernandez , Peter Sadowski , John A. Shepherd

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

In order to support the creation of reliable machine learning models for anomaly detection, this project focuses on preprocessing, enhancing, and organizing a medical imaging dataset. There are two classifications in the dataset: normal and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Dharanidharan S , Suhitha Renuka S , Ajishi Singh , Sheena Christabel Pravin

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Measuring the confidence of AI models is critical for safely deploying AI in real-world industrial systems. One important application of confidence measurement is information extraction from scanned documents. However, there exists no…

Information Retrieval · Computer Science 2022-10-11 Bao-Sinh Nguyen , Quang-Bach Tran , Tuan-Anh Nguyen Dang , Duc Nguyen , Hung Le

Automatically determining the position of every slice in a CT scan is a basic yet powerful capability allowing fast retrieval of region of interest for visual inspection and automated analysis. Unlike conventional localization approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Amit Oved

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani
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