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We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

Materials Science · Physics 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

Our understanding of organs at risk is progressing to include physical small tissues such as coronary arteries and the radiosensitivities of many small organs and tissues are high. Therefore, the accurate segmentation of small volumes in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Jianxin Zhou , Kadishe Fejza , Massimiliano Salvatori , Daniele Della Latta , Gregory M. Hermann , Angela Di Fulvio

The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue…

Biological Physics · Physics 2026-02-24 Li Xiao , Liqing Liu , Hongjun Wu , Jiayi Zhong , Xixia Li , Yan Zhang , Junjie Hu , Sun Fei , Ge Yang , Tao Xu

Accurate instance-level segmentation of organelles in electron microscopy (EM) is critical for quantitative analysis of subcellular morphology and inter-organelle interactions. However, current benchmarks, based on small, curated datasets,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yanrui Lu , Danyang Chen , Haowen Xiao , Jiarui Zhu , Fukang Ge , Binqian Zou , Jiali Guan , Jiayin Liang , Yuting Wang , Ziqian Guan , Xiangcheng Bao , Jinhao Bi , Lin Gu , Jun He , Yingying Zhu

Whole abdominal organ segmentation is important in diagnosing abdomen lesions, radiotherapy, and follow-up. However, oncologists' delineating all abdominal organs from 3D volumes is time-consuming and very expensive. Deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Xiangde Luo , Wenjun Liao , Jianghong Xiao , Jieneng Chen , Tao Song , Xiaofan Zhang , Kang Li , Dimitris N. Metaxas , Guotai Wang , Shaoting Zhang

Multi-organ segmentation, which identifies and separates different organs in medical images, is a fundamental task in medical image analysis. Recently, the immense success of deep learning motivated its wide adoption in multi-organ…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Jiahua Dong , Guohua Cheng , Yue Zhang , Chengtao Peng , Yu Song , Ruofeng Tong , Lanfen Lin , Yen-Wei Chen

Efficient and accurate multi-organ segmentation from abdominal CT volumes is a fundamental challenge in medical image analysis. Existing 3D segmentation approaches are computationally and memory intensive, often processing entire volumes…

Image and Video Processing · Electrical Eng. & Systems 2025-05-19 Hania Ghouse , Muzammil Behzad

Organoids are self-organized 3D cell clusters that closely mimic the architecture and function of in vivo tissues and organs. Quantification of organoid morphology helps in studying organ development, drug discovery, and toxicity…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Xiaodan Xing , Chunling Tang , Yunzhe Guo , Nicholas Kurniawan , Guang Yang

Precise delineation of multiple organs or abnormal regions in the human body from medical images plays an essential role in computer-aided diagnosis, surgical simulation, image-guided interventions, and especially in radiotherapy treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Shiman Li , Haoran Wang , Yucong Meng , Chenxi Zhang , Zhijian Song

The analysis of dynamic organelles remains a formidable challenge, though key to understanding biological processes. We introduce Nellie, an automated and unbiased user-friendly pipeline for segmentation, tracking, and feature extraction of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Austin E. Y. T. Lefebvre , Gabriel Sturm , Ting-Yu Lin , Emily Stoops , Magdalena Preciado Lopez , Benjamin Kaufmann-Malaga , Kayley Hake

Multi-organ segmentation of 3D medical images is fundamental with meaningful applications in various clinical automation pipelines. Although deep learning has achieved superior performance, the time and memory consumption of segmenting the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Xueqi Guo , Halid Ziya Yerebakan , Yoshihisa Shinagawa , Kritika Iyer , Gerardo Hermosillo Valadez

Deep learning-based segmentation and classification are crucial to large-scale biomedical imaging, particularly for 3D data, where manual analysis is impractical. Although many methods exist, selecting suitable models and tuning parameters…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 David Exler , Joaquin Eduardo Urrutia Gómez , Martin Krüger , Maike Schliephake , John Jbeily , Mario Vitacolonna , Rüdiger Rudolf , Markus Reischl

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

Three-dimensional (3D) ultrasound imaging can overcome the limitations of conventional two dimensional (2D) ultrasound imaging in structural observation and measurement. However, conducting volumetric ultrasound imaging for large-sized…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Caozhe Li , Enxiang Shen , Haoyang Wang , Yuxin Wang , Jie Yuan , Li Gong , Di Zhao , Weijing Zhang , Zhibin Jin

Annotation is a major hurdle in the semantic segmentation of microscopy images and volumes due to its prerequisite expertise and effort. This work enables the training of semantic segmentation networks on images with only a single point for…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Shijie Li , Neel Dey , Katharina Bermond , Leon von der Emde , Christine A. Curcio , Thomas Ach , Guido Gerig

Organ segmentation is a fundamental task in medical imaging since it is useful for many clinical automation pipelines. However, some tasks do not require full segmentation. Instead, a classifier can identify the selected organ without…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Halid Ziya Yerebakan , Yoshihisa Shinagawa , Gerardo Hermosillo Valadez

Epithelial cells form diverse structures from squamous spherical organoids to densely packed pseudostratified tissues. Quantification of cellular properties in these contexts requires high-resolution deep imaging and computational…

Quantitative Methods · Quantitative Biology 2025-02-03 G. Paci , P. Vicente-Munuera , I. Fernandez-Mosquera , A. Miranda , K. Lau , Q. Zhang , R. Barrientos , Y. Mao

Weakly supervised segmentation is an important problem in medical image analysis due to the high cost of pixelwise annotation. Prior methods, while often focusing on weak labels of 2D images, exploit few structural cues of volumetric…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Qian He , Shuailin Li , Xuming He

Vision Language Models (VLMs) have demonstrated remarkable performance in open-world zero-shot visual recognition. However, their potential in space-related applications remains largely unexplored. In the space domain, accurate manual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Samet Hicsonmez , Jose Sosa , Dan Pineau , Inder Pal Singh , Arunkumar Rathinam , Abd El Rahman Shabayek , Djamila Aouada

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi
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