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Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Many recent medical segmentation systems rely on powerful deep learning models to solve highly specific tasks. To maximize performance, it is standard practice to evaluate numerous pipelines with varying model topologies, optimization…

Machine Learning · Computer Science 2019-11-06 Mathias Perslev , Erik Bjørnager Dam , Akshay Pai , Christian Igel

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

Existing approaches for the problem of ultrasound image segmentation, whether supervised or semi-supervised, are typically specialized for specific anatomical structures or tasks, limiting their practical utility in clinical settings. In…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yaxiong Chen , Qicong Wang , Chunlei Li , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Due to the intensive cost of labor and expertise in annotating 3D medical images at a voxel level, most benchmark datasets are equipped with the annotations of only one type of organs and/or tumors, resulting in the so-called partially…

Computer Vision and Pattern Recognition · Computer Science 2020-11-23 Jianpeng Zhang , Yutong Xie , Yong Xia , Chunhua Shen

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

We propose a novel hands-free method to interactively segment 3D medical volumes. In our scenario, a human user progressively segments an organ by answering a series of questions of the form "Is this voxel inside the object to segment?". At…

Computer Vision and Pattern Recognition · Computer Science 2016-09-21 Florian Dubost , Loic Peter , Christian Rupprecht , Benjamin Gutierrez-Becker , Nassir Navab

Deep learning has shown great promise in the ability to automatically annotate organs in magnetic resonance imaging (MRI) scans, for example, of the brain. However, despite advancements in the field, the ability to accurately segment…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Cosmin Ciausu , Deepa Krishnaswamy , Benjamin Billot , Steve Pieper , Ron Kikinis , Andrey Fedorov

The objective of this paper is to significantly reduce the manual workload required from medical professionals in complex 3D segmentation tasks that cannot be yet fully automated. For instance, in radiotherapy planning, organs at risk must…

Deep neural networks enable highly accurate image segmentation, but require large amounts of manually annotated data for supervised training. Few-shot learning aims to address this shortcoming by learning a new class from a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Abhijit Guha Roy , Shayan Siddiqui , Sebastian Pölsterl , Nassir Navab , Christian Wachinger

Despite the considerable progress in automatic abdominal multi-organ segmentation from CT/MRI scans in recent years, a comprehensive evaluation of the models' capabilities is hampered by the lack of a large-scale benchmark from diverse…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Yuanfeng Ji , Haotian Bai , Jie Yang , Chongjian Ge , Ye Zhu , Ruimao Zhang , Zhen Li , Lingyan Zhang , Wanling Ma , Xiang Wan , Ping Luo

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Segmentation of multiple organs-at-risk (OARs) is essential for radiation therapy treatment planning and other clinical applications. We developed an Automated deep Learning-based Abdominal Multi-Organ segmentation (ALAMO) framework based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-25 Yuhua Chen , Dan Ruan , Jiayu Xiao , Lixia Wang , Bin Sun , Rola Saouaf , Wensha Yang , Debiao Li , Zhaoyang Fan

Recent advances in bioimaging have provided scientists a superior high spatial-temporal resolution to observe dynamics of living cells as 3D volumetric videos. Unfortunately, the 3D biomedical video analysis is lagging, impeded by resource…

Computer Vision and Pattern Recognition · Computer Science 2021-06-23 Mengyang Zhao , Quan Liu , Aadarsh Jha , Ruining Deng , Tianyuan Yao , Anita Mahadevan-Jansen , Matthew J. Tyska , Bryan A. Millis , Yuankai Huo

Automatic localization and segmentation of organs-at-risk (OAR) in CT are essential pre-processing steps in medical image analysis tasks, such as radiation therapy planning. For instance, the segmentation of OAR surrounding tumors enables…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Fernando Navarro , Guido Sasahara , Suprosanna Shit , Ivan Ezhov , Jan C. Peeken , Stephanie E. Combs , Bjoern H. Menze

Reconstructing a synaptic wiring diagram, or connectome, from electron microscopy (EM) images of brain tissue currently requires many hours of manual annotation or proofreading (Kasthuri and Lichtman, 2010; Lichtman and Sanes, 2008; Seung,…

Optimal surface segmentation is a state-of-the-art method used for segmentation of multiple globally optimal surfaces in volumetric datasets. The method is widely used in numerous medical image segmentation applications. However, nodes in…

Computer Vision and Pattern Recognition · Computer Science 2019-02-18 Abhay Shah , Michael D. Abramoff , Xiaodong Wu

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

This paper presents a new technique for the virtual reality (VR) visu-alization of complex volume images obtained from computer tomography (CT) and Magnetic Resonance Imaging (MRI) by combining three-dimensional (3D) mesh processing and…

Multimedia · Computer Science 2023-05-02 Iva Vasic , Roberto Pierdicca , Emanuele Frontoni , Bata Vasic

The lack of sufficient annotated image data is a common issue in medical image segmentation. For some organs and densities, the annotation may be scarce, leading to poor model training convergence, while other organs have plenty of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anastasia Makarevich , Azade Farshad , Vasileios Belagiannis , Nassir Navab