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Plasmonic nanopores hold a significant promise for molecular sequencing, but their sensitivity and temporal resolution are constrained by limited signal strength and rapid translocation of molecules through the pore. Here we report an…

Optics · Physics 2026-05-12 Nageswar Reddy Sanamreddy , Paolo Vavassori

Extracting the sequence information of DNA from the blocked ionic current is the crucial step of the ionic current-based nanopore sequencing approaches. The thinnest graphene nanopore, which contained only one layer of carbon atoms,…

Biological Physics · Physics 2014-01-29 Wenping Lv , Ren'an Wu

The translocation of a polymer through a pore in a membrane separating fluids of different viscosities is studied via several computational approaches. Starting with the polymer halfway, we find that as a viscosity difference across the…

Soft Condensed Matter · Physics 2013-04-17 Hendrick W. de Haan , Gary W. Slater

Ion channels regulate many essential properties of biological cells, especially the membrane potential. Despite decades of efforts on artificial channels, it remains a great challenge to mimic the dipole potential-an indispensable…

We present micro-rheological measurments of the drag force on colloids pulled through a solution of lambda-DNA (used here as a monodisperse model polymer) with an optical tweezer. The experiments show a violation of the Stokes-Einstein…

Soft Condensed Matter · Physics 2009-11-13 Christof Gutsche , Friedrich Kremer , Matthias Krüger , Markus Rauscher , Rudolf Weeber , Jens Harting

We report translocation experiments on double-strand DNA through a silicon oxide nanopore. Samples containing DNA fragments with seven different lengths between 2000 to 96000 basepairs have been electrophoretically driven through a 10 nm…

Biomolecules · Quantitative Biology 2015-06-26 Arnold J. Storm , Cornelis Storm , Jianghua Chen , Henny Zandbergen , Jean-Francois Joanny , Cees Dekker

Langevin Dynamics simulations of polymer translocation are performed where the polymer is stretched via two opposing forces applied on the first and last monomer before and during translocation. In this setup, polymer translocation is…

Soft Condensed Matter · Physics 2018-08-08 Hendrick W. de Haan , David Sean , Gary W. Slater

Molecular dynamics simulation is utilized to investigate the ionic transport of NaCl in solution through a graphene nanopore under an applied electric field. Results show the formation of concentration polarization layers in the vicinity of…

Biological Physics · Physics 2013-01-10 Guohui Hu , Mao Mao , Sandip Ghosal

Nanoscale electronic transport gives rise to a number of intriguing physical phenomena that are accompanied by distinct spatial patterns of current flow. Here, we report on sensitive magnetic imaging of two-dimensional current distributions…

Mesoscale and Nanoscale Physics · Physics 2022-06-17 M. L. Palm , W. S. Huxter , P. Welter , S. Ernst , P. J. Scheidegger , S. Diesch , K. Chang , P. Rickhaus , T. Taniguchi , K. Wantanabe , K. Ensslin , C. L. Degen

We develop a theory for polymer translocation driven by a time-dependent force through an oscillating nanopore. To this end, we extend the iso-flux tension propagation theory (IFTP) [Sarabadani \textit{et al., J. Chem. Phys.}, 2014,…

Statistical Mechanics · Physics 2015-09-02 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

The adsorption of DNA or other polyelectrolyte molecules on charged membranes is a recurrent motif in soft matter and bionanotechnological systems. Two typical situations encountered are the deposition of single DNA chains onto substrates…

Soft Condensed Matter · Physics 2016-10-19 Sahin Buyukdagli , Ralf Blossey

Ionic transport in nanopores or nanochannels is key to many cellular processes and is now being explored as a method for DNA/polymer sequencing and detection. Although apparently simple in its scope, the study of ionic dynamics in confined…

Mesoscale and Nanoscale Physics · Physics 2013-06-13 Andrew Meyertholen , Massimiliano Di Ventra

We present a simplified model of the dynamics of translocation of RNA through a nanopore which only allows the passage of unbound nucleotides. In particular, we consider the disorder averaged translocation dynamics of random, two-component,…

Biomolecules · Quantitative Biology 2007-05-23 J. B. Lucks , Y. Kafri

Short nanopores find extensive applications capitalizing on their high throughput and detection resolution. Ionic behaviors through long nanopores are mainly determined by charged inner-pore walls. When pore lengths decrease to sub-200 nm,…

Chemical Physics · Physics 2024-02-19 Long Ma , Zhe Liu , Bowen Ai , Jia Man , Jianyong Li , Kechen Wu , Yinghua Qiu

We demonstrate the use of the magnetic-field-dependence of highly spatially confined, GHz-frequency ferromagnetic resonances in a ferromagnetic nanostructure for the detection of adsorbed magnetic nanoparticles. This is achieved in a large…

We investigate the translocation of stiff polymers in the presence of binding particles through a nanopore by two-dimensional Langevin dynamics simulations. We find that the mean translocation time shows a minimum as a function of the…

Soft Condensed Matter · Physics 2015-06-12 Wancheng Yu , Yiding Ma , Kaifu Luo

In recent years polymer translocation, i.e., transport of polymeric molecules through nanometer-sized pores and channels embedded in membranes, has witnessed strong advances. It is now possible to observe single-molecule polymer dynamics…

Soft Condensed Matter · Physics 2013-09-13 Debabrata Panja , Gerard T. Barkema , Anatoly B. Kolomeisky

Ion transport in highly-confined space is important to various applications, such as biosensing and seawater desalination with nanopores. All-atom molecular dynamics simulations are conducted to investigate the transport of Na$^+$ and…

Mesoscale and Nanoscale Physics · Physics 2019-07-30 Zhongwu Li , Yinghua Qiu , Yan Zhang , Min Yue , Yunfei Chen

The ionic selectivity of nanopores is crucial for the energy conversion based on nanoporous membranes. It can be significantly affected by various parameters of nanopores and the applied fields driving ions through porous membranes. Here,…

Soft Condensed Matter · Physics 2024-10-29 Chao Zhang , Mengnan Guo , Hongwen Zhang , Xiuhua Ren , Yinghao Gao , Yinghua Qiu

We present electrical measurements of high-frequency magnetic dynamics excited by spin-polarized currents in Co/Cu/Ni80Fe20 nanopillar devices, with a magnetic field applied perpendicular to the sample layers. As a function of current and…