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Concept bottleneck models (CBMs) are interpretable neural networks that first predict labels for human-interpretable concepts relevant to the prediction task, and then predict the final label based on the concept label predictions. We…

Machine Learning · Computer Science 2023-04-28 Kushal Chauhan , Rishabh Tiwari , Jan Freyberg , Pradeep Shenoy , Krishnamurthy Dvijotham

Investigating uncertainties in computer simulations can be prohibitive in terms of computational costs, since the simulator needs to be run over a large number of input values. Building an emulator, i.e. a statistical surrogate model of the…

Methodology · Statistics 2022-10-18 Ayao Ehara , Serge Guillas

Determining the best model or models for a particular data set, a process known as Bayesian model comparison, is a critical part of probabilistic inference. Typically, this process assumes a fixed model-space (that is, a fixed set of…

Quantitative Methods · Quantitative Biology 2019-01-08 Thomas HB FitzGerald , Dorothea Hammerer , Thomas D Sambrook , Will D Penny

Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a truly optimal dose. because early response is not a perfect…

Applications · Statistics 2024-04-03 Cheng-Han Yang , Peter F. Thall , Ruitao Lin

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

Optimal design for model training is a critical topic in machine learning. Active Learning aims at obtaining improved models by querying samples with maximum uncertainty according to the estimation model for artificially labeling; this has…

Dynamic and evolving operational and economic environments present significant challenges for decision-making. We explore a simulation optimization problem characterized by non-stationary input distributions with regime-switching dynamics…

Optimization and Control · Mathematics 2025-08-19 Jianglin Xia , Haowei Wang , Songhao Wang , Szu Hui Ng

Understanding how people allocate visual attention is central to Human-Computer Interaction (HCI), yet existing computational models of attention are often either descriptive, task-specific, or difficult to interpret. My dissertation…

Human-Computer Interaction · Computer Science 2026-03-03 Yunpeng Bai

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Bayesian optimal experimental design has immense potential to inform the collection of data so as to subsequently enhance our understanding of a variety of processes. However, a major impediment is the difficulty in evaluating optimal…

Computation · Statistics 2018-03-14 David J. Price , Nigel G. Bean , Joshua V. Ross , Jonathan Tuke

Uncertainty is prevalent in robotics. Due to measurement noise and complex dynamics, we cannot estimate the exact system and environment state. Since conservative motion planners are not guaranteed to find a safe control strategy in a…

Robotics · Computer Science 2023-09-22 Laura Lützow , Yue Meng , Andres Chavez Armijos , Chuchu Fan

The polarization of opinions, information segregation, and cognitive biases on social media have attracted significant academic attention. In real-world networks, information often spans multiple interrelated topics, posing challenges for…

Artificial Intelligence · Computer Science 2025-10-15 Dingyi Zuo , Hongjie Zhang , Jie Ou , Chaosheng Feng , Shuwan Liu

The test bench time needed for model-based calibration can be reduced with active learning methods for test design. This paper presents an improved strategy for active output selection. This is the task of learning multiple models in the…

Machine Learning · Computer Science 2021-01-12 Adrian Prochaska , Julien Pillas , Bernard Bäker

In nested simulation literature, a common assumption is that the experimenter can choose the number of outer scenarios to sample. This paper considers the case when the experimenter is given a fixed set of outer scenarios from an external…

Methodology · Statistics 2024-05-14 Mingbin Ben Feng , Eunhye Song

There has been considerable recent interest in interpretable concept-based models such as Concept Bottleneck Models (CBMs), which first predict human-interpretable concepts and then map them to output classes. To reduce reliance on…

Machine Learning · Computer Science 2024-07-08 Simon Schrodi , Julian Schur , Max Argus , Thomas Brox

We consider the problem of sequentially making decisions that are rewarded by "successes" and "failures" which can be predicted through an unknown relationship that depends on a partially controllable vector of attributes for each instance.…

Machine Learning · Statistics 2017-09-18 Yingfei Wang , Chu Wang , Warren Powell

In order to gain a mechanistic understanding of how tinnitus emerges in the brain, we must build biologically plausible computational models that mimic both tinnitus development and perception, and test the tentative models with brain and…

Neurons and Cognition · Quantitative Biology 2020-10-06 Patrick Krauss , Achim Schilling

Concept Bottleneck Models (CBMs) provide a basis for semantic abstractions within a neural network architecture. Such models have primarily been seen through the lens of interpretability so far, wherein they offer transparency by inferring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Deepika SN Vemuri , Gautham Bellamkonda , Aditya Pola , Vineeth N Balasubramanian

We introduce CODS (Computational Optimization in Design Space), a theoretical model that frames computational design as a constrained optimization problem over a structured, multi-dimensional design space. Unlike existing methods that rely…

Human-Computer Interaction · Computer Science 2025-06-24 Nan Cao , Xiaoyu Qi , Chuer Chen , Xiaoke Yan

A dataset is a shred of crucial evidence to describe a task. However, each data point in the dataset does not have the same potential, as some of the data points can be more representative or informative than others. This unequal importance…

Machine Learning · Computer Science 2022-03-21 Jaehong Yoon , Divyam Madaan , Eunho Yang , Sung Ju Hwang