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One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Clinical data is fundamental to advance neurosurgical research, but access is often constrained by data availability, small sample sizes, privacy regulations, and resource-intensive preprocessing and de-identification procedures. Synthetic…

Computation and Language · Computer Science 2025-10-21 Austin A. Barr , Eddie Guo , Emre Sezgin

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

Modelling disease outbreak models remains challenging due to incomplete surveillance data, noise, and limited access to standardized datasets. We have created BIGBOY1.2, an open synthetic dataset generator that creates configurable epidemic…

Populations and Evolution · Quantitative Biology 2025-08-12 Raunak Narwal , Syed Abbas

The vast amount of available medical records has the potential to improve healthcare and biomedical research. However, privacy restrictions make these data accessible for internal use only. Recent works have addressed this problem by…

Computation and Language · Computer Science 2025-01-31 Samuel Belkadi , Libo Ren , Nicolo Micheletti , Lifeng Han , Goran Nenadic

Although highly valuable for a variety of applications, urban mobility data is rarely made openly available as it contains sensitive personal information. Synthetic data aims to solve this issue by generating artificial data that resembles…

Cryptography and Security · Computer Science 2024-07-15 Alexandra Kapp , Julia Hansmeyer , Helena Mihaljević

Currently, there are many difficulties regarding the interoperability of medical data and related population data sources. These complications get in the way of the generation of high-quality data sets at city, region and national levels.…

Computers and Society · Computer Science 2023-10-13 Anna Andreychenko , Viktoriia Korzhuk , Stanislav Kondratenko , Polina Cheraneva

Synthetic data generation, a cornerstone of Generative Artificial Intelligence, promotes a paradigm shift in data science by addressing data scarcity and privacy while enabling unprecedented performance. As synthetic data becomes more…

Machine Learning · Statistics 2024-03-12 Xiaotong Shen , Yifei Liu , Rex Shen

Clinical image interpretation is inherently multi-step and tool-centric: clinicians iteratively combine visual evidence with patient context, quantify findings, and refine their decisions through a sequence of specialized procedures. While…

Artificial Intelligence · Computer Science 2026-03-09 Lin Fan , Pengyu Dai , Zhipeng Deng , Haolin Wang , Xun Gong , Yefeng Zheng , Yafei Ou

Flexible and natural nonverbal reactions to human behavior remain a challenge for socially interactive agents (SIAs) that are predominantly animated using hand-crafted rules. While recently proposed machine learning based approaches to…

Human-Computer Interaction · Computer Science 2024-02-14 Daksitha Withanage Don , Philipp Müller , Fabrizio Nunnari , Elisabeth André , Patrick Gebhard

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

The generation of synthetic data is a promising technology to make medical data available for secondary use in a privacy-compliant manner. A popular method for creating realistic patient data is the rule-based Synthea data generator.…

Generating realistic synthetic electronic health records (EHRs) holds tremendous promise for accelerating healthcare research, facilitating AI model development and enhancing patient privacy. However, existing generative methods typically…

Machine Learning · Computer Science 2025-07-28 Guanglin Zhou , Sebastiano Barbieri

With the recent success of deep learning algorithms, many researchers have focused on generative models for human motion animation. However, the research community lacks a platform for training and benchmarking various algorithms, and the…

Graphics · Computer Science 2021-12-14 Yizhou Zhao , Wensi Ai , Liang Qiu , Pan Lu , Feng Shi , Tian Han , Song-Chun Zhu

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

Imitation learning is a promising paradigm for training robot control policies, but these policies can suffer from distribution shift, where the conditions at evaluation time differ from those in the training data. A popular approach for…

Robotics · Computer Science 2024-05-03 Ryan Hoque , Ajay Mandlekar , Caelan Garrett , Ken Goldberg , Dieter Fox

Understanding the world in first-person view is fundamental in Augmented Reality (AR). This immersive perspective brings dramatic visual changes and unique challenges compared to third-person views. Synthetic data has empowered…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Gen Li , Kaifeng Zhao , Siwei Zhang , Xiaozhong Lyu , Mihai Dusmanu , Yan Zhang , Marc Pollefeys , Siyu Tang

Generative models have been showing potential for producing data in mass. This study explores the enhancement of clinical natural language processing performance by utilizing synthetic data generated from advanced language models. Promising…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Jack Gallifant , Marco Guevara , Yanjun Gao , Majid Afshar , Timothy Miller , Dmitriy Dligach , Danielle S. Bitterman

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

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