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Accurate gross tumor volume segmentation on multi-modal medical data is critical for radiotherapy planning in nasopharyngeal carcinoma and glioblastoma. Recent advances in deep neural networks have brought promising results in medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Jingyun Yang , Guoqing Zhang , Jingge Wang , Yang Li

Language use differs between domains and even within a domain, language use changes over time. For pre-trained language models like BERT, domain adaptation through continued pre-training has been shown to improve performance on in-domain…

Computation and Language · Computer Science 2021-09-09 Paul Röttger , Janet B. Pierrehumbert

We hypothesize that large language models (LLMs) based on the transformer architecture can enable automated detection of clinical phenotype terms, including terms not documented in the HPO. In this study, we developed two types of models:…

Quantitative Methods · Quantitative Biology 2023-11-10 Jingye Yang , Cong Liu , Wendy Deng , Da Wu , Chunhua Weng , Yunyun Zhou , Kai Wang

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

The biomedical domain has sparked a significant interest in the field of Natural Language Processing (NLP), which has seen substantial advancements with pre-trained language models (PLMs). However, comparing these models has proven…

In medical image segmentation, domain generalization poses a significant challenge due to domain shifts caused by variations in data acquisition devices and other factors. These shifts are particularly pronounced in the most common…

Computer Vision and Pattern Recognition · Computer Science 2023-11-06 Ruxue Wen , Hangjie Yuan , Dong Ni , Wenbo Xiao , Yaoyao Wu

Deep learning models tend to underperform in the presence of domain shifts. Domain transfer has recently emerged as a promising approach wherein images exhibiting a domain shift are transformed into other domains for augmentation or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Weinan Song , Gaurav Fotedar , Nima Tajbakhsh , Ziheng Zhou , Lei He , Xiaowei Ding

Objective: Clinical deep phenotyping and phenotype annotation play a critical role in both the diagnosis of patients with rare disorders as well as in building computationally-tractable knowledge in the rare disorders field. These processes…

Neural networks are known to be data hungry and domain sensitive, but it is nearly impossible to obtain large quantities of labeled data for every domain we are interested in. This necessitates the use of domain adaptation strategies. One…

Computation and Language · Computer Science 2019-10-08 Zi-Yi Dou , Xinyi Wang , Junjie Hu , Graham Neubig

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

Clinical text classification requires choosing between specialized fine-tuned models (BERT variants) and general-purpose large language models (LLMs), yet neither dominates across all instances. We introduce Learning to Defer for clinical…

Computation and Language · Computer Science 2026-04-16 Rishik Kondadadi , John E. Ortega

The objective of this study is to develop natural language processing (NLP) models that can analyze patients' drug reviews and accurately classify their satisfaction levels as positive, neutral, or negative. Such models would reduce the…

Computation and Language · Computer Science 2023-08-09 Yue Ling

Unsupervised domain adaptation leverages abundant labeled data from various source domains to generalize onto unlabeled target data. Prior research has primarily focused on learning domain-invariant features across the source and target…

Computation and Language · Computer Science 2025-03-10 Jie He , Wendi Zhou , Xiang Lorraine Li , Jeff Z. Pan

Single source domain generalization (SDG) holds promise for more reliable and consistent image segmentation across real-world clinical settings particularly in the medical domain, where data privacy and acquisition cost constraints often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Deep neural networks (DNNs) have been widely used for medical image analysis. However, the lack of access a to large-scale annotated dataset poses a great challenge, especially in the case of rare diseases, or new domains for the research…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Sungho Suh , Sojeong Cheon , Wonseo Choi , Yeon Woong Chung , Won-Kyung Cho , Ji-Sun Paik , Sung Eun Kim , Dong-Jin Chang , Yong Oh Lee

Post-Traumatic Stress Disorder (PTSD) remains underdiagnosed in clinical settings, presenting opportunities for automated detection to identify patients. This study evaluates natural language processing approaches for detecting PTSD from…

Computation and Language · Computer Science 2026-01-08 Feng Chen , Dror Ben-Zeev , Gillian Sparks , Arya Kadakia , Trevor Cohen

Media bias is a multi-faceted construct influencing individual behavior and collective decision-making. Slanted news reporting is the result of one-sided and polarized writing which can occur in various forms. In this work, we focus on an…

Computation and Language · Computer Science 2022-05-24 Jan-David Krieger , Timo Spinde , Terry Ruas , Juhi Kulshrestha , Bela Gipp

Contextual word embedding models such as ELMo (Peters et al., 2018) and BERT (Devlin et al., 2018) have dramatically improved performance for many natural language processing (NLP) tasks in recent months. However, these models have been…

Computation and Language · Computer Science 2019-06-24 Emily Alsentzer , John R. Murphy , Willie Boag , Wei-Hung Weng , Di Jin , Tristan Naumann , Matthew B. A. McDermott

Medical caption prediction which can be regarded as a task of medical report generation (MRG), requires the automatic generation of coherent and accurate captions for the given medical images. However, the scarcity of labelled medical…

Computer Vision and Pattern Recognition · Computer Science 2023-06-12 Bang Yang , Asif Raza , Yuexian Zou , Tong Zhang

Numerous Deep Learning (DL) classification models have been developed for a large spectrum of medical image analysis applications, which promises to reshape various facets of medical practice. Despite early advances in DL model validation…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Sarah Matta , Mathieu Lamard , Philippe Zhang , Alexandre Le Guilcher , Laurent Borderie , Béatrice Cochener , Gwenolé Quellec